Manda2019 - Acute hepatitis B virus infection model within the host incorporating immune cells and cytokine response Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_unresolved_infection_observable_1",
        "label": "Initial Unresolved Infection Observable 1",
        "units": "native source value",
        "default": 9600000,
        "maps_to": "immunology_sbml_manda2019_acute_hepatitis_b_virus_infection_mode_model1911280002_model.initial_unresolved_infection_observable_1",
        "description": "Initial Unresolved Infection Observable 1. Sets the initial value of bundled SBML species `H`."
      },
      {
        "name": "initial_unresolved_infection_observable_2",
        "label": "Initial Unresolved Infection Observable 2",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_manda2019_acute_hepatitis_b_virus_infection_mode_model1911280002_model.initial_unresolved_infection_observable_2",
        "description": "Initial Unresolved Infection Observable 2. Sets the initial value of bundled SBML species `I_H`."
      },
      {
        "name": "initial_unresolved_infection_observable_3",
        "label": "Initial Unresolved Infection Observable 3",
        "units": "native source value",
        "default": 1000,
        "maps_to": "immunology_sbml_manda2019_acute_hepatitis_b_virus_infection_mode_model1911280002_model.initial_unresolved_infection_observable_3",
        "description": "Initial Unresolved Infection Observable 3. Sets the initial value of bundled SBML species `T_c`."
      },
      {
        "name": "initial_unresolved_infection_observable_4",
        "label": "Initial Unresolved Infection Observable 4",
        "units": "native source value",
        "default": 1000,
        "maps_to": "immunology_sbml_manda2019_acute_hepatitis_b_virus_infection_mode_model1911280002_model.initial_unresolved_infection_observable_4",
        "description": "Initial Unresolved Infection Observable 4. Sets the initial value of bundled SBML species `T_1`."
      },
      {
        "name": "initial_unresolved_infection_observable_5",
        "label": "Initial Unresolved Infection Observable 5",
        "units": "native source value",
        "default": 1000,
        "maps_to": "immunology_sbml_manda2019_acute_hepatitis_b_virus_infection_mode_model1911280002_model.initial_unresolved_infection_observable_5",
        "description": "Initial Unresolved Infection Observable 5. Sets the initial value of bundled SBML species `T_2`."
      },
      {
        "name": "hepatocyte_growth_rate",
        "label": "Hepatocyte Growth Rate",
        "units": "native source value",
        "default": 0.00145,
        "maps_to": "immunology_sbml_manda2019_acute_hepatitis_b_virus_infection_mode_model1911280002_model.hepatocyte_growth_rate",
        "description": "Hepatocyte Growth Rate. Sets bundled SBML parameter `r`."
      },
      {
        "name": "hepatocyte_infection_rate",
        "label": "Hepatocyte Infection Rate",
        "units": "native source value",
        "default": 9.9e-10,
        "maps_to": "immunology_sbml_manda2019_acute_hepatitis_b_virus_infection_mode_model1911280002_model.hepatocyte_infection_rate",
        "description": "Hepatocyte Infection Rate. Sets bundled SBML parameter `beta`."
      },
      {
        "name": "infected_hepatocytes_death_rate",
        "label": "Infected Hepatocytes Death Rate",
        "units": "native source value",
        "default": 0.4,
        "maps_to": "immunology_sbml_manda2019_acute_hepatitis_b_virus_infection_mode_model1911280002_model.infected_hepatocytes_death_rate",
        "description": "Infected Hepatocytes Death Rate. Sets bundled SBML parameter `mu`."
      },
      {
        "name": "th1_death_rate",
        "label": "Th1 Death Rate",
        "units": "native source value",
        "default": 0.5,
        "maps_to": "immunology_sbml_manda2019_acute_hepatitis_b_virus_infection_mode_model1911280002_model.th1_death_rate",
        "description": "Th1 Death Rate. Sets bundled SBML parameter `mu_1`."
      },
      {
        "name": "th2_death_rate",
        "label": "Th2 Death Rate",
        "units": "native source value",
        "default": 0.5,
        "maps_to": "immunology_sbml_manda2019_acute_hepatitis_b_virus_infection_mode_model1911280002_model.th2_death_rate",
        "description": "Th2 Death Rate. Sets bundled SBML parameter `mu_2`."
      }
    ],
    "outputs": [
      {
        "name": "unresolved_infection_observable_1",
        "maps_to": "immunology_sbml_manda2019_acute_hepatitis_b_virus_infection_mode_model1911280002_model.unresolved_infection_observable_1"
      },
      {
        "name": "unresolved_infection_observable_2",
        "maps_to": "immunology_sbml_manda2019_acute_hepatitis_b_virus_infection_mode_model1911280002_model.unresolved_infection_observable_2"
      },
      {
        "name": "unresolved_infection_observable_3",
        "maps_to": "immunology_sbml_manda2019_acute_hepatitis_b_virus_infection_mode_model1911280002_model.unresolved_infection_observable_3"
      },
      {
        "name": "unresolved_infection_observable_4",
        "maps_to": "immunology_sbml_manda2019_acute_hepatitis_b_virus_infection_mode_model1911280002_model.unresolved_infection_observable_4"
      },
      {
        "name": "unresolved_infection_observable_5",
        "maps_to": "immunology_sbml_manda2019_acute_hepatitis_b_virus_infection_mode_model1911280002_model.unresolved_infection_observable_5"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_manda2019_acute_hepatitis_b_virus_infection_mode_model1911280002_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_manda2019_acute_hepatitis_b_virus_infection_mode_model1911280002_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_manda2019_acute_hepatitis_b_virus_infection_mode_model1911280002_model.species_labels"
      }
    ]
  },
  "title": "Manda2019 - Acute hepatitis B virus infection model within the host incorporating immune cells and cytokine response Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "immunology_sbml_manda2019_acute_hepatitis_b_virus_infection_mode_model1911280002_model"
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_manda2019_acute_hepatitis_b_virus_infection_mode_model1911280002_model_state"
      ],
      "from": "immunology_sbml_manda2019_acute_hepatitis_b_virus_infection_mode_model1911280002_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_manda2019_acute_hepatitis_b_virus_infection_mode_model1911280002_model_summary"
      ],
      "from": "immunology_sbml_manda2019_acute_hepatitis_b_virus_infection_mode_model1911280002_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_manda2019_acute_hepatitis_b_virus_infection_mode_model1911280002_model_species_labels"
      ],
      "from": "immunology_sbml_manda2019_acute_hepatitis_b_virus_infection_mode_model1911280002_model.species_labels"
    }
  ],
  "package": "manda2019-acute-hepatitis-b-virus-infection-model-within",
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "version": "1.0.0",
  "description": "This is a within-host hepatitis B viral mathematical model for hepatitis B in the acute phase of infection. The model incorporates hepatocytes, hepatitis B virus, immune system cells and cytokine dyna.",
  "schema_version": "2.0"
}