About lab
One published Lab
Build with this Lab. Run it anywhere.
Use the same immutable release locally or through managed cloud execution, with its exact version and provenance preserved.
Preparing exact examples…
Single-model lab wrapper for Tyson2001_Cell_Cycle_Regulation. This model describes the budding yeast cell cycle model used in fig 8 a in Regulation of the eukaryotic cell cycle: molecular antagonism, hysteresis, and irreversible transitions. It can be used to explore cell-cycle regulation dynamics and compare checkpoint behavior across conditions.
Manifest
{
"io": {
"inputs": [],
"outputs": [
{
"name": "cyclin_bt",
"label": "Cyclin Bt",
"maps_to": "cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model.cyclin_bt",
"description": "Tracks Cyclin Bt in the lab model via `cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model.cyclin_bt`."
},
{
"name": "active_cdc20",
"label": "Active Cdc20",
"maps_to": "cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model.active_cdc20",
"description": "Tracks Active Cdc20 in the lab model via `cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model.active_cdc20`."
},
{
"name": "cdh1_apc_c_activator",
"label": "Cdh1 APC/C activator",
"maps_to": "cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model.cdh1_apc_c_activator",
"description": "Tracks Cdh1 APC/C activator in the lab model via `cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model.cdh1_apc_c_activator`."
},
{
"name": "model_state_m_m",
"label": "Model state M (m)",
"maps_to": "cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model.model_state_m_m",
"description": "Tracks Model state M (m) in the lab model via `cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model.model_state_m_m`."
},
{
"name": "total_cdc20_apc_c_activator",
"label": "Total Cdc20 APC/C activator",
"maps_to": "cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model.total_cdc20_apc_c_activator",
"description": "Tracks Total Cdc20 APC/C activator in the lab model via `cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model.total_cdc20_apc_c_activator`."
},
{
"name": "phosphorylated_ie",
"label": "Phosphorylated IE",
"maps_to": "cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model.phosphorylated_ie",
"description": "Tracks Phosphorylated IE in the lab model via `cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model.phosphorylated_ie`."
},
{
"name": "total_cyclin_dependent_kinase_inhibitor",
"label": "Total cyclin-dependent kinase inhibitor",
"maps_to": "cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model.total_cyclin_dependent_kinase_inhibitor",
"description": "Tracks Total cyclin-dependent kinase inhibitor in the lab model via `cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model.total_cyclin_dependent_kinase_inhibitor`."
},
{
"name": "model_state_sk",
"label": "Model state SK",
"maps_to": "cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model.model_state_sk",
"description": "Tracks Model state SK in the lab model via `cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model.model_state_sk`."
},
{
"name": "cyclin_b",
"label": "Cyclin B",
"maps_to": "cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model.cyclin_b",
"description": "Tracks Cyclin B in the lab model via `cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model.cyclin_b`."
},
{
"name": "trimer_complex",
"label": "Trimer complex",
"maps_to": "cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model.trimer_complex",
"description": "Tracks Trimer complex in the lab model via `cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model.trimer_complex`."
},
{
"name": "mad_spindle_checkpoint_signal",
"label": "Mad spindle checkpoint signal",
"maps_to": "cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model.mad_spindle_checkpoint_signal",
"description": "Tracks Mad spindle checkpoint signal in the lab model via `cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model.mad_spindle_checkpoint_signal`."
}
]
},
"title": "Tyson2001_Cell_Cycle_Regulation Lab",
"models": [
{
"path": "models/core",
"alias": "cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model_state"
],
"from": "cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model.state"
},
{
"to": [
"visualisation.cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model_summary"
],
"from": "cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model.summary"
},
{
"to": [
"visualisation.cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model_species_labels"
],
"from": "cellcycle_sbml_tyson2001_cell_cycle_regulation_biomd0000000195_model.species_labels"
}
],
"package": "tyson2001-budding-yeast-regulation",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "Single-model lab wrapper for Tyson2001_Cell_Cycle_Regulation. This model describes the budding yeast cell cycle model used in fig 8 a in Regulation of the eukaryotic cell cycle: molecular antagonism, hysteresis, and irreversible transitions. It can be used to explore cell-cycle regulation dynamics and compare checkpoint behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagetyson2001-budding-yeast-regulation
Created2026-05-15
Updated2026-06-13
cellcyclesbmlbiomodels_ebifaithfulvisualisationother