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This model was used for instationary 13C metabolic flux analysis of the extracellular GL-GNT by-pass of E. It can be used to explore metabolic flux dynamics and compare pathway behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_microbial_metabolism_state_1",
"units": "native SBML value",
"default": 1,
"maps_to": "metabolism_sbml_millard2023_gluconolactone_gluconate_extracellul_model2310250001_model.initial_microbial_metabolism_state_1",
"description": "Initial condition for microbial metabolism state 1. Maps to bundled SBML symbol `G6P_0`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
},
{
"name": "initial_microbial_metabolism_state_2",
"units": "native SBML value",
"default": 1,
"maps_to": "metabolism_sbml_millard2023_gluconolactone_gluconate_extracellul_model2310250001_model.initial_microbial_metabolism_state_2",
"description": "Initial condition for microbial metabolism state 2. Maps to bundled SBML symbol `GAP_0`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
},
{
"name": "initial_microbial_metabolism_state_3",
"units": "native SBML value",
"default": 1,
"maps_to": "metabolism_sbml_millard2023_gluconolactone_gluconate_extracellul_model2310250001_model.initial_microbial_metabolism_state_3",
"description": "Initial condition for microbial metabolism state 3. Maps to bundled SBML symbol `PYR_0`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
},
{
"name": "initial_observable_6pgl_0",
"units": "native SBML value",
"default": 1,
"maps_to": "metabolism_sbml_millard2023_gluconolactone_gluconate_extracellul_model2310250001_model.initial_observable_6pgl_0",
"description": "Initial condition for observable 6pgl 0. Maps to bundled SBML symbol `_6PGL_0`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
},
{
"name": "initial_observable_6pg_0",
"units": "native SBML value",
"default": 1,
"maps_to": "metabolism_sbml_millard2023_gluconolactone_gluconate_extracellul_model2310250001_model.initial_observable_6pg_0",
"description": "Initial condition for observable 6pg 0. Maps to bundled SBML symbol `_6PG_0`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
}
],
"outputs": [
{
"name": "microbial_metabolism_state_1",
"maps_to": "metabolism_sbml_millard2023_gluconolactone_gluconate_extracellul_model2310250001_model.microbial_metabolism_state_1"
},
{
"name": "microbial_metabolism_state_2",
"maps_to": "metabolism_sbml_millard2023_gluconolactone_gluconate_extracellul_model2310250001_model.microbial_metabolism_state_2"
},
{
"name": "microbial_metabolism_state_3",
"maps_to": "metabolism_sbml_millard2023_gluconolactone_gluconate_extracellul_model2310250001_model.microbial_metabolism_state_3"
},
{
"name": "observable_6pgl_0",
"maps_to": "metabolism_sbml_millard2023_gluconolactone_gluconate_extracellul_model2310250001_model.observable_6pgl_0"
},
{
"name": "observable_6pg_0",
"maps_to": "metabolism_sbml_millard2023_gluconolactone_gluconate_extracellul_model2310250001_model.observable_6pg_0"
},
{
"name": "observable_values",
"maps_to": "metabolism_sbml_millard2023_gluconolactone_gluconate_extracellul_model2310250001_model.observable_values"
},
{
"name": "run_summary",
"maps_to": "metabolism_sbml_millard2023_gluconolactone_gluconate_extracellul_model2310250001_model.run_summary"
},
{
"name": "observable_labels",
"maps_to": "metabolism_sbml_millard2023_gluconolactone_gluconate_extracellul_model2310250001_model.observable_labels"
}
]
},
"title": "Millard2023 - Gluconolactone-Gluconate extracellular bypass in Escherichia coli Lab",
"models": [
{
"path": "models/core",
"alias": "metabolism_sbml_millard2023_gluconolactone_gluconate_extracellul_model2310250001_model",
"parameters": {
"model_path": "data/MODEL2310250001.xml",
"integration_step": 0.1
}
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.metabolism_sbml_millard2023_gluconolactone_gluconate_extracellul_model2310250001_model_observable_values"
],
"from": "metabolism_sbml_millard2023_gluconolactone_gluconate_extracellul_model2310250001_model.observable_values"
},
{
"to": [
"visualisation.metabolism_sbml_millard2023_gluconolactone_gluconate_extracellul_model2310250001_model_run_summary"
],
"from": "metabolism_sbml_millard2023_gluconolactone_gluconate_extracellul_model2310250001_model.run_summary"
},
{
"to": [
"visualisation.metabolism_sbml_millard2023_gluconolactone_gluconate_extracellul_model2310250001_model_observable_labels"
],
"from": "metabolism_sbml_millard2023_gluconolactone_gluconate_extracellul_model2310250001_model.observable_labels"
}
],
"package": "millard2023-gluconolactone-gluconate-extracellular-bypa-0a99e889",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "This model was used for instationary 13C metabolic flux analysis of the extracellular GL-GNT by-pass of E. It can be used to explore metabolic flux dynamics and compare pathway behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagemillard2023-gluconolactone-gluconate-extracellular-bypa-0a99e889
Created2026-05-15
Updated2026-06-13
biomodels_ebifaithfulmetabolismodesbmltelluriumvisualisationother