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Clean Biosimulant lab for systems signaling model: Heiland2019 - NAD pathway model analysing the impact of NNMT on pathway dynamics and evolution. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_adp",
"label": "Initial ADP",
"maps_to": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model.initial_adp",
"description": "Initial level of ADP. Maps to SBML symbol `ADP`; exposed as a traceable initial-condition perturbation."
},
{
"name": "initial_amp",
"label": "Initial AMP",
"maps_to": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model.initial_amp",
"description": "Initial level of AMP. Maps to SBML symbol `AMP`; exposed as a traceable initial-condition perturbation."
},
{
"name": "initial_atp",
"label": "Initial ATP",
"maps_to": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model.initial_atp",
"description": "Initial level of ATP. Maps to SBML symbol `ATP`; exposed as a traceable initial-condition perturbation."
}
],
"outputs": [
{
"name": "nicotinate_mononucleotide",
"label": "nicotinate mononucleotide",
"maps_to": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model.nicotinate_mononucleotide",
"description": "nicotinate mononucleotide. Maps to SBML symbol `NaMN` and is emitted in native SBML units."
},
{
"name": "nicotinamide",
"label": "nicotinamide",
"maps_to": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model.nicotinamide",
"description": "nicotinamide. Maps to SBML symbol `NAM` and is emitted in native SBML units."
},
{
"name": "nad",
"label": "NAD",
"maps_to": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model.nad",
"description": "NAD. Maps to SBML symbol `NAD` and is emitted in native SBML units."
},
{
"name": "state",
"label": "Observable state",
"maps_to": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model.state"
},
{
"name": "summary",
"label": "Simulation summary",
"maps_to": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model.summary"
},
{
"name": "species_labels",
"label": "Observable labels",
"maps_to": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model.species_labels"
}
]
},
"tags": [
"signaling",
"systems",
"systems-biology",
"sbml",
"faithful",
"biomodels_ebi",
"cellular-signaling"
],
"title": "Heiland2019 - NAD pathway model analysing the impact of NNMT on pathway dynamics and evolution Lab",
"models": [
{
"path": "models/core",
"alias": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model_state"
],
"from": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model.state"
},
{
"to": [
"visualisation.signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model_summary"
],
"from": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model.summary"
},
{
"to": [
"visualisation.signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model_species_labels"
],
"from": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model.species_labels"
}
],
"package": "heiland2019-nad-pathway-model-analysing-the-impa",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "Clean Biosimulant lab for systems signaling model: Heiland2019 - NAD pathway model analysing the impact of NNMT on pathway dynamics and evolution. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packageheiland2019-nad-pathway-model-analysing-the-impa
Created2026-05-16
Updated2026-06-13
signalingsystemssystems-biologysbmlfaithfulbiomodels_ebicellular-signalingvisualisationother