Lockwood2006 - Application Clinical Trial Simulation Compare Proof Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_drug_clearance_cc",
        "label": "Initial Drug Clearance Cc",
        "maps_to": "physiology_cellml_lockwood_ewy_hermann_holford_2006_lockwoodewyhermannholford2006_model.initial_drug_clearance_cc",
        "description": "Initial value for Drug Clearance Cc. Maps to source symbol `CC`. Units: mg_per_litre. Naming evidence: source symbol, component, or units provide a direct public name.",
        "accepted_units": [
          "mg_per_litre"
        ]
      },
      {
        "name": "initial_drug_clearance_pc",
        "label": "Initial Drug Clearance Pc",
        "maps_to": "physiology_cellml_lockwood_ewy_hermann_holford_2006_lockwoodewyhermannholford2006_model.initial_drug_clearance_pc",
        "description": "Initial value for Drug Clearance Pc. Maps to source symbol `PC`. Units: mg_per_litre. Naming evidence: source symbol, component, or units provide a direct public name.",
        "accepted_units": [
          "mg_per_litre"
        ]
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Selected Source State",
        "maps_to": "physiology_cellml_lockwood_ewy_hermann_holford_2006_lockwoodewyhermannholford2006_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation Summary",
        "maps_to": "physiology_cellml_lockwood_ewy_hermann_holford_2006_lockwoodewyhermannholford2006_model.summary"
      },
      {
        "name": "trajectory",
        "label": "Source Trajectory",
        "maps_to": "physiology_cellml_lockwood_ewy_hermann_holford_2006_lockwoodewyhermannholford2006_model.trajectory"
      },
      {
        "name": "variable_labels",
        "label": "Observable Labels",
        "maps_to": "physiology_cellml_lockwood_ewy_hermann_holford_2006_lockwoodewyhermannholford2006_model.variable_labels"
      },
      {
        "name": "drug_clearance_cc",
        "label": "Drug Clearance Cc",
        "maps_to": "physiology_cellml_lockwood_ewy_hermann_holford_2006_lockwoodewyhermannholford2006_model.drug_clearance_cc",
        "description": "Drug Clearance Cc. Maps to source symbol `CC`. Units: mg_per_litre. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "drug_clearance_pc",
        "label": "Drug Clearance Pc",
        "maps_to": "physiology_cellml_lockwood_ewy_hermann_holford_2006_lockwoodewyhermannholford2006_model.drug_clearance_pc",
        "description": "Drug Clearance Pc. Maps to source symbol `PC`. Units: mg_per_litre. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "model_state_a_in",
        "label": "Model State A In (source A_in)",
        "maps_to": "physiology_cellml_lockwood_ewy_hermann_holford_2006_lockwoodewyhermannholford2006_model.model_state_a_in",
        "description": "Model State A In (source A_in). Maps to source symbol `A_in`. Units: mg. Naming evidence: source symbol is too ambiguous for a stronger public label."
      },
      {
        "name": "beta_a",
        "label": "Beta A",
        "maps_to": "physiology_cellml_lockwood_ewy_hermann_holford_2006_lockwoodewyhermannholford2006_model.beta_a",
        "description": "Beta A. Maps to source symbol `beta_a`. Units: units_ml_per_ng. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "ce_a",
        "label": "Ce A",
        "maps_to": "physiology_cellml_lockwood_ewy_hermann_holford_2006_lockwoodewyhermannholford2006_model.ce_a",
        "description": "Ce A. Maps to source symbol `CeA`. Units: ng_per_ml. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "cl_ic",
        "label": "Cl Ic",
        "maps_to": "physiology_cellml_lockwood_ewy_hermann_holford_2006_lockwoodewyhermannholford2006_model.cl_ic",
        "description": "Cl Ic. Maps to source symbol `CL_ic`. Units: litre_per_day. Naming evidence: source symbol, component, or units provide a direct public name."
      }
    ]
  },
  "title": "Lockwood2006 - Application Clinical Trial Simulation Compare Proof Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "physiology_cellml_lockwood_ewy_hermann_holford_2006_lockwoodewyhermannholford2006_model",
      "parameters": {
        "model_path": "data/lockwood_ewy_hermann_holford_2006.cellml",
        "integration_step": 0.01
      }
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.physiology_cellml_lockwood_ewy_hermann_holford_2006_lockwoodewyhermannholford2006_model_state"
      ],
      "from": "physiology_cellml_lockwood_ewy_hermann_holford_2006_lockwoodewyhermannholford2006_model.state"
    },
    {
      "to": [
        "visualisation.physiology_cellml_lockwood_ewy_hermann_holford_2006_lockwoodewyhermannholford2006_model_summary"
      ],
      "from": "physiology_cellml_lockwood_ewy_hermann_holford_2006_lockwoodewyhermannholford2006_model.summary"
    },
    {
      "to": [
        "visualisation.physiology_cellml_lockwood_ewy_hermann_holford_2006_lockwoodewyhermannholford2006_model_trajectory"
      ],
      "from": "physiology_cellml_lockwood_ewy_hermann_holford_2006_lockwoodewyhermannholford2006_model.trajectory"
    },
    {
      "to": [
        "visualisation.physiology_cellml_lockwood_ewy_hermann_holford_2006_lockwoodewyhermannholford2006_model_variable_labels"
      ],
      "from": "physiology_cellml_lockwood_ewy_hermann_holford_2006_lockwoodewyhermannholford2006_model.variable_labels"
    }
  ],
  "package": "lockwood2006-application-clinical-trial-simulation-compare-proof",
  "runtime": {
    "duration": 0.01,
    "settle_steps": 1,
    "initial_inputs": {},
    "communication_step": 0.01
  },
  "version": "1.0.0",
  "description": "Source-faithful physiology lab for Lockwood, Ewy, Hermann, Holford, 2006. Public controls and outputs are mapped to real source symbols for pharmacokinetics.",
  "schema_version": "2.0"
}