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This a model from the article: Computational model for effects of ligand/receptor binding properties oninterleukin-2 trafficking dynamics and T cell proliferation response. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_rs_0",
"label": "Initial Rs 0",
"units": "native source value",
"default": 1500,
"maps_to": "immunology_sbml_fallon2000_interleukin_2_dynamics_biomd0000000665_model.initial_rs_0",
"description": "Initial Rs 0. Sets the initial value of bundled SBML species `Rs_0`."
},
{
"name": "initial_cs_0",
"label": "Initial Cs 0",
"units": "native source value",
"default": 1,
"maps_to": "immunology_sbml_fallon2000_interleukin_2_dynamics_biomd0000000665_model.initial_cs_0",
"description": "Initial Cs 0. Sets the initial value of bundled SBML species `Cs_0`."
},
{
"name": "initial_ri_0",
"label": "Initial Ri 0",
"units": "native source value",
"default": 300,
"maps_to": "immunology_sbml_fallon2000_interleukin_2_dynamics_biomd0000000665_model.initial_ri_0",
"description": "Initial Ri 0. Sets the initial value of bundled SBML species `Ri_0`."
},
{
"name": "initial_ci_0",
"label": "Initial Ci 0",
"units": "native source value",
"default": 1,
"maps_to": "immunology_sbml_fallon2000_interleukin_2_dynamics_biomd0000000665_model.initial_ci_0",
"description": "Initial Ci 0. Sets the initial value of bundled SBML species `Ci_0`."
},
{
"name": "initial_li_0",
"label": "Initial Li 0",
"units": "native source value",
"default": 0.01,
"maps_to": "immunology_sbml_fallon2000_interleukin_2_dynamics_biomd0000000665_model.initial_li_0",
"description": "Initial Li 0. Sets the initial value of bundled SBML species `Li_0`."
}
],
"outputs": [
{
"name": "rs_0",
"maps_to": "immunology_sbml_fallon2000_interleukin_2_dynamics_biomd0000000665_model.rs_0"
},
{
"name": "cs_0",
"maps_to": "immunology_sbml_fallon2000_interleukin_2_dynamics_biomd0000000665_model.cs_0"
},
{
"name": "ri_0",
"maps_to": "immunology_sbml_fallon2000_interleukin_2_dynamics_biomd0000000665_model.ri_0"
},
{
"name": "ci_0",
"maps_to": "immunology_sbml_fallon2000_interleukin_2_dynamics_biomd0000000665_model.ci_0"
},
{
"name": "li_0",
"maps_to": "immunology_sbml_fallon2000_interleukin_2_dynamics_biomd0000000665_model.li_0"
},
{
"name": "state",
"maps_to": "immunology_sbml_fallon2000_interleukin_2_dynamics_biomd0000000665_model.state"
},
{
"name": "summary",
"maps_to": "immunology_sbml_fallon2000_interleukin_2_dynamics_biomd0000000665_model.summary"
},
{
"name": "species_labels",
"maps_to": "immunology_sbml_fallon2000_interleukin_2_dynamics_biomd0000000665_model.species_labels"
}
]
},
"title": "Fallon2000 - Interleukin-2 dynamics Lab",
"models": [
{
"path": "models/core",
"alias": "immunology_sbml_fallon2000_interleukin_2_dynamics_biomd0000000665_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.immunology_sbml_fallon2000_interleukin_2_dynamics_biomd0000000665_model_state"
],
"from": "immunology_sbml_fallon2000_interleukin_2_dynamics_biomd0000000665_model.state"
},
{
"to": [
"visualisation.immunology_sbml_fallon2000_interleukin_2_dynamics_biomd0000000665_model_summary"
],
"from": "immunology_sbml_fallon2000_interleukin_2_dynamics_biomd0000000665_model.summary"
},
{
"to": [
"visualisation.immunology_sbml_fallon2000_interleukin_2_dynamics_biomd0000000665_model_species_labels"
],
"from": "immunology_sbml_fallon2000_interleukin_2_dynamics_biomd0000000665_model.species_labels"
}
],
"package": "fallon2000-interleukin-2-dynamics",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "This a model from the article: Computational model for effects of ligand/receptor binding properties oninterleukin-2 trafficking dynamics and T cell proliferation response. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagefallon2000-interleukin-2-dynamics
Created2026-05-15
Updated2026-06-13
immunologysbmlbiomodels_ebifaithfulcuratedvisualisationother