Andersen2017 - Mathematical modelling as a proof of concept for MPNs as a human inflammation model for cancer development Lab
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This is a mathematical model investigating the role of chronic inflammation in the development and progression of myeloproliferative neoplasms (MPNs). The model describes the proliferation from stem c.
Manifest
{
"io": {
"inputs": [
{
"name": "inflammation_level",
"label": "Inflammation Level",
"units": "native SBML value",
"default": 7,
"maps_to": "oncology_sbml_andersen2017_mathematical_modelling_as_a_proof_o_biomd0000000852_model.inflammation_level",
"description": "Inflammation Level. Overrides bundled SBML parameter `inflammation`."
}
],
"outputs": [
{
"name": "x0",
"maps_to": "oncology_sbml_andersen2017_mathematical_modelling_as_a_proof_o_biomd0000000852_model.x0",
"description": "X0 observable. Maps to SBML symbol `x0`."
},
{
"name": "x1",
"maps_to": "oncology_sbml_andersen2017_mathematical_modelling_as_a_proof_o_biomd0000000852_model.x1",
"description": "X1 observable. Maps to SBML symbol `x1`."
},
{
"name": "a",
"maps_to": "oncology_sbml_andersen2017_mathematical_modelling_as_a_proof_o_biomd0000000852_model.a",
"description": "A observable. Maps to SBML symbol `a`."
},
{
"name": "s",
"maps_to": "oncology_sbml_andersen2017_mathematical_modelling_as_a_proof_o_biomd0000000852_model.s",
"description": "S observable. Maps to SBML symbol `s`."
},
{
"name": "y0",
"maps_to": "oncology_sbml_andersen2017_mathematical_modelling_as_a_proof_o_biomd0000000852_model.y0",
"description": "Y0 observable. Maps to SBML symbol `y0`."
},
{
"name": "y1",
"maps_to": "oncology_sbml_andersen2017_mathematical_modelling_as_a_proof_o_biomd0000000852_model.y1",
"description": "Y1 observable. Maps to SBML symbol `y1`."
},
{
"name": "state",
"maps_to": "oncology_sbml_andersen2017_mathematical_modelling_as_a_proof_o_biomd0000000852_model.state",
"description": "Full raw SBML observable record for reproducibility and downstream visualisation."
},
{
"name": "summary",
"maps_to": "oncology_sbml_andersen2017_mathematical_modelling_as_a_proof_o_biomd0000000852_model.summary",
"description": "Change and peak summary across the simulated SBML observables."
},
{
"name": "species_labels",
"maps_to": "oncology_sbml_andersen2017_mathematical_modelling_as_a_proof_o_biomd0000000852_model.species_labels",
"description": "Mapping from selected raw SBML observable symbols to display labels."
}
]
},
"tags": [
"biomodels_ebi",
"curated",
"faithful",
"oncology",
"physiology",
"sbml",
"systemsbiology",
"tumor-growth"
],
"title": "Andersen2017 - Mathematical modelling as a proof of concept for MPNs as a human inflammation model for cancer development Lab",
"models": [
{
"path": "models/core",
"alias": "oncology_sbml_andersen2017_mathematical_modelling_as_a_proof_o_biomd0000000852_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.oncology_sbml_andersen2017_mathematical_modelling_as_a_proof_o_biomd0000000852_model_state"
],
"from": "oncology_sbml_andersen2017_mathematical_modelling_as_a_proof_o_biomd0000000852_model.state"
},
{
"to": [
"visualisation.oncology_sbml_andersen2017_mathematical_modelling_as_a_proof_o_biomd0000000852_model_summary"
],
"from": "oncology_sbml_andersen2017_mathematical_modelling_as_a_proof_o_biomd0000000852_model.summary"
},
{
"to": [
"visualisation.oncology_sbml_andersen2017_mathematical_modelling_as_a_proof_o_biomd0000000852_model_species_labels"
],
"from": "oncology_sbml_andersen2017_mathematical_modelling_as_a_proof_o_biomd0000000852_model.species_labels"
}
],
"package": "andersen2017-mathematical-modelling-as-a-proof-of-conce-182c1d3b",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "This is a mathematical model investigating the role of chronic inflammation in the development and progression of myeloproliferative neoplasms (MPNs). The model describes the proliferation from stem c.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packageandersen2017-mathematical-modelling-as-a-proof-of-conce-182c1d3b
Created2026-05-16
Updated2026-06-13
biomodels_ebicuratedfaithfuloncologyphysiologysbmlsystemsbiologytumor-growthvisualisationother