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Baris Hancioglu, David Swigon & Gilles Clermont. A dynamical model of human immune response to influenza A virus infection.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_viral_load_v",
"label": "Initial Viral Load V",
"units": "native source value",
"default": 0.01,
"maps_to": "immunology_sbml_hancioglu2007_human_immune_response_to_influenza_biomd0000000711_model.initial_viral_load_v",
"description": "Initial Viral Load V. Sets the initial value of bundled SBML species `Viral_Load__V`."
},
{
"name": "initial_infected_epithelial_cells_i",
"label": "Initial Infected Epithelial Cells I",
"units": "native source value",
"default": 0,
"maps_to": "immunology_sbml_hancioglu2007_human_immune_response_to_influenza_biomd0000000711_model.initial_infected_epithelial_cells_i",
"description": "Initial Infected Epithelial Cells I. Sets the initial value of bundled SBML species `Infected_Epithelial_cells__I`."
},
{
"name": "initial_healthy_epithelial_cells_h",
"label": "Initial Healthy Epithelial Cells H",
"units": "native source value",
"default": 1,
"maps_to": "immunology_sbml_hancioglu2007_human_immune_response_to_influenza_biomd0000000711_model.initial_healthy_epithelial_cells_h",
"description": "Initial Healthy Epithelial Cells H. Sets the initial value of bundled SBML species `Healthy_Epithelial_cells__H`."
},
{
"name": "initial_antigen_presenting_cell_cells_m",
"label": "Initial Antigen Presenting Cell Cells M",
"units": "native source value",
"default": 0,
"maps_to": "immunology_sbml_hancioglu2007_human_immune_response_to_influenza_biomd0000000711_model.initial_antigen_presenting_cell_cells_m",
"description": "Initial Antigen Presenting Cell Cells M. Sets the initial value of bundled SBML species `APC_cells__M`."
},
{
"name": "initial_interferons_f",
"label": "Initial Interferons F",
"units": "native source value",
"default": 0,
"maps_to": "immunology_sbml_hancioglu2007_human_immune_response_to_influenza_biomd0000000711_model.initial_interferons_f",
"description": "Initial Interferons F. Sets the initial value of bundled SBML species `Interferons__F`."
}
],
"outputs": [
{
"name": "viral_load_v",
"maps_to": "immunology_sbml_hancioglu2007_human_immune_response_to_influenza_biomd0000000711_model.viral_load_v"
},
{
"name": "infected_epithelial_cells_i",
"maps_to": "immunology_sbml_hancioglu2007_human_immune_response_to_influenza_biomd0000000711_model.infected_epithelial_cells_i"
},
{
"name": "healthy_epithelial_cells_h",
"maps_to": "immunology_sbml_hancioglu2007_human_immune_response_to_influenza_biomd0000000711_model.healthy_epithelial_cells_h"
},
{
"name": "antigen_presenting_cell_cells_m",
"maps_to": "immunology_sbml_hancioglu2007_human_immune_response_to_influenza_biomd0000000711_model.antigen_presenting_cell_cells_m"
},
{
"name": "interferons_f",
"maps_to": "immunology_sbml_hancioglu2007_human_immune_response_to_influenza_biomd0000000711_model.interferons_f"
},
{
"name": "state",
"maps_to": "immunology_sbml_hancioglu2007_human_immune_response_to_influenza_biomd0000000711_model.state"
},
{
"name": "summary",
"maps_to": "immunology_sbml_hancioglu2007_human_immune_response_to_influenza_biomd0000000711_model.summary"
},
{
"name": "species_labels",
"maps_to": "immunology_sbml_hancioglu2007_human_immune_response_to_influenza_biomd0000000711_model.species_labels"
}
]
},
"title": "Hancioglu2007 - Human Immune Response to Influenza A virus Infection Lab",
"models": [
{
"path": "models/core",
"alias": "immunology_sbml_hancioglu2007_human_immune_response_to_influenza_biomd0000000711_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.immunology_sbml_hancioglu2007_human_immune_response_to_influenza_biomd0000000711_model_state"
],
"from": "immunology_sbml_hancioglu2007_human_immune_response_to_influenza_biomd0000000711_model.state"
},
{
"to": [
"visualisation.immunology_sbml_hancioglu2007_human_immune_response_to_influenza_biomd0000000711_model_summary"
],
"from": "immunology_sbml_hancioglu2007_human_immune_response_to_influenza_biomd0000000711_model.summary"
},
{
"to": [
"visualisation.immunology_sbml_hancioglu2007_human_immune_response_to_influenza_biomd0000000711_model_species_labels"
],
"from": "immunology_sbml_hancioglu2007_human_immune_response_to_influenza_biomd0000000711_model.species_labels"
}
],
"package": "hancioglu2007-human-immune-response-to-influenza-a-virus",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "Baris Hancioglu, David Swigon & Gilles Clermont. A dynamical model of human immune response to influenza A virus infection.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagehancioglu2007-human-immune-response-to-influenza-a-virus
Created2026-05-15
Updated2026-06-13
immunologysbmlbiomodels_ebifaithfulcuratedvisualisationother