Green2024 - whole-body vitamin A metabolism in humans Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_vitamin_a_metabolism_state_1",
        "units": "native SBML value",
        "default": 0.04343260815,
        "maps_to": "metabolism_sbml_green2024_whole_body_vitamin_a_metabolism_in_hum_model2411290001_model.initial_vitamin_a_metabolism_state_1",
        "description": "Initial condition for vitamin a metabolism state 1. Maps to bundled SBML symbol `M_1`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_vitamin_a_metabolism_state_2",
        "units": "native SBML value",
        "default": 0.04300258233,
        "maps_to": "metabolism_sbml_green2024_whole_body_vitamin_a_metabolism_in_hum_model2411290001_model.initial_vitamin_a_metabolism_state_2",
        "description": "Initial condition for vitamin a metabolism state 2. Maps to bundled SBML symbol `M_2`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_vitamin_a_metabolism_state_3",
        "units": "native SBML value",
        "default": 1.36312171,
        "maps_to": "metabolism_sbml_green2024_whole_body_vitamin_a_metabolism_in_hum_model2411290001_model.initial_vitamin_a_metabolism_state_3",
        "description": "Initial condition for vitamin a metabolism state 3. Maps to bundled SBML symbol `M_4`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_vitamin_a_metabolism_state_4",
        "units": "native SBML value",
        "default": 3.361993214,
        "maps_to": "metabolism_sbml_green2024_whole_body_vitamin_a_metabolism_in_hum_model2411290001_model.initial_vitamin_a_metabolism_state_4",
        "description": "Initial condition for vitamin a metabolism state 4. Maps to bundled SBML symbol `M_5`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_vitamin_a_metabolism_state_5",
        "units": "native SBML value",
        "default": 920.4583274,
        "maps_to": "metabolism_sbml_green2024_whole_body_vitamin_a_metabolism_in_hum_model2411290001_model.initial_vitamin_a_metabolism_state_5",
        "description": "Initial condition for vitamin a metabolism state 5. Maps to bundled SBML symbol `M_6`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      }
    ],
    "outputs": [
      {
        "name": "vitamin_a_metabolism_state_1",
        "maps_to": "metabolism_sbml_green2024_whole_body_vitamin_a_metabolism_in_hum_model2411290001_model.vitamin_a_metabolism_state_1"
      },
      {
        "name": "vitamin_a_metabolism_state_2",
        "maps_to": "metabolism_sbml_green2024_whole_body_vitamin_a_metabolism_in_hum_model2411290001_model.vitamin_a_metabolism_state_2"
      },
      {
        "name": "vitamin_a_metabolism_state_3",
        "maps_to": "metabolism_sbml_green2024_whole_body_vitamin_a_metabolism_in_hum_model2411290001_model.vitamin_a_metabolism_state_3"
      },
      {
        "name": "vitamin_a_metabolism_state_4",
        "maps_to": "metabolism_sbml_green2024_whole_body_vitamin_a_metabolism_in_hum_model2411290001_model.vitamin_a_metabolism_state_4"
      },
      {
        "name": "vitamin_a_metabolism_state_5",
        "maps_to": "metabolism_sbml_green2024_whole_body_vitamin_a_metabolism_in_hum_model2411290001_model.vitamin_a_metabolism_state_5"
      },
      {
        "name": "observable_values",
        "maps_to": "metabolism_sbml_green2024_whole_body_vitamin_a_metabolism_in_hum_model2411290001_model.observable_values"
      },
      {
        "name": "run_summary",
        "maps_to": "metabolism_sbml_green2024_whole_body_vitamin_a_metabolism_in_hum_model2411290001_model.run_summary"
      },
      {
        "name": "observable_labels",
        "maps_to": "metabolism_sbml_green2024_whole_body_vitamin_a_metabolism_in_hum_model2411290001_model.observable_labels"
      }
    ]
  },
  "title": "Green2024 - whole-body vitamin A metabolism in humans Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "metabolism_sbml_green2024_whole_body_vitamin_a_metabolism_in_hum_model2411290001_model",
      "parameters": {
        "model_path": "data/MODEL2411290001.xml",
        "integration_step": 0.1
      }
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.metabolism_sbml_green2024_whole_body_vitamin_a_metabolism_in_hum_model2411290001_model_observable_values"
      ],
      "from": "metabolism_sbml_green2024_whole_body_vitamin_a_metabolism_in_hum_model2411290001_model.observable_values"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_green2024_whole_body_vitamin_a_metabolism_in_hum_model2411290001_model_run_summary"
      ],
      "from": "metabolism_sbml_green2024_whole_body_vitamin_a_metabolism_in_hum_model2411290001_model.run_summary"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_green2024_whole_body_vitamin_a_metabolism_in_hum_model2411290001_model_observable_labels"
      ],
      "from": "metabolism_sbml_green2024_whole_body_vitamin_a_metabolism_in_hum_model2411290001_model.observable_labels"
    }
  ],
  "package": "green2024-whole-body-vitamin-a-metabolism-in-humans",
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "version": "1.0.0",
  "description": "Metabolism Green2024Whole Body Vitamin AMetabolism In Hum Model2411290001Model models core biological dynamics as a OTHER simulation curated from biomodels_ebi (biomodels_ebi:MODEL2411290001), focused on metabo. When you run it, you can track state over time and compare response patterns across parameter settings.",
  "schema_version": "2.0"
}