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This a model from the article: Synergism of coupled subsarcolemmal Ca2+ clocks and sarcolemmal voltage clocksconfers robust and flexible pacemaker function in a novel pacemaker cell model. It can be used to explore systemsbiology maltsev2009 pacemakercellmodel nonsteadystate model1006230069 dynamics and compare simulation behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_vm_vm",
"label": "Initial Vm Vm",
"maps_to": "systemsbiology_sbml_maltsev2009_pacemakercellmodel_nonsteadystate_model1006230069_model.initial_vm_vm",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Vm_Vm`."
},
{
"name": "initial_model_state_ri",
"label": "Initial Model State Ri",
"maps_to": "systemsbiology_sbml_maltsev2009_pacemakercellmodel_nonsteadystate_model1006230069_model.initial_model_state_ri",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `RI`."
},
{
"name": "initial_r_j_sr_carel",
"label": "Initial R J Sr Carel",
"maps_to": "systemsbiology_sbml_maltsev2009_pacemakercellmodel_nonsteadystate_model1006230069_model.initial_r_j_sr_carel",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `R_j_SRCarel`."
},
{
"name": "initial_model_state_qi",
"label": "Initial Model State Qi",
"maps_to": "systemsbiology_sbml_maltsev2009_pacemakercellmodel_nonsteadystate_model1006230069_model.initial_model_state_qi",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `qi`."
},
{
"name": "initial_model_state_qa",
"label": "Initial Model State Qa",
"maps_to": "systemsbiology_sbml_maltsev2009_pacemakercellmodel_nonsteadystate_model1006230069_model.initial_model_state_qa",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `qa`."
},
{
"name": "initial_model_state_pi",
"label": "Initial Model State Pi",
"maps_to": "systemsbiology_sbml_maltsev2009_pacemakercellmodel_nonsteadystate_model1006230069_model.initial_model_state_pi",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `pi_`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_maltsev2009_pacemakercellmodel_nonsteadystate_model1006230069_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_maltsev2009_pacemakercellmodel_nonsteadystate_model1006230069_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_maltsev2009_pacemakercellmodel_nonsteadystate_model1006230069_model.species_labels"
},
{
"name": "vm_vm",
"maps_to": "systemsbiology_sbml_maltsev2009_pacemakercellmodel_nonsteadystate_model1006230069_model.vm_vm"
},
{
"name": "model_state_ri",
"maps_to": "systemsbiology_sbml_maltsev2009_pacemakercellmodel_nonsteadystate_model1006230069_model.model_state_ri"
},
{
"name": "r_j_sr_carel",
"maps_to": "systemsbiology_sbml_maltsev2009_pacemakercellmodel_nonsteadystate_model1006230069_model.r_j_sr_carel"
},
{
"name": "model_state_qi",
"maps_to": "systemsbiology_sbml_maltsev2009_pacemakercellmodel_nonsteadystate_model1006230069_model.model_state_qi"
},
{
"name": "model_state_qa",
"maps_to": "systemsbiology_sbml_maltsev2009_pacemakercellmodel_nonsteadystate_model1006230069_model.model_state_qa"
},
{
"name": "model_state_pi",
"maps_to": "systemsbiology_sbml_maltsev2009_pacemakercellmodel_nonsteadystate_model1006230069_model.model_state_pi"
}
]
},
"tags": [
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Maltsev2009 Pacemakercellmodel Nonsteadystate Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_maltsev2009_pacemakercellmodel_nonsteadystate_model1006230069_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_maltsev2009_pacemakercellmodel_nonsteadystate_model1006230069_model_state"
],
"from": "systemsbiology_sbml_maltsev2009_pacemakercellmodel_nonsteadystate_model1006230069_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_maltsev2009_pacemakercellmodel_nonsteadystate_model1006230069_model_summary"
],
"from": "systemsbiology_sbml_maltsev2009_pacemakercellmodel_nonsteadystate_model1006230069_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_maltsev2009_pacemakercellmodel_nonsteadystate_model1006230069_model_species_labels"
],
"from": "systemsbiology_sbml_maltsev2009_pacemakercellmodel_nonsteadystate_model1006230069_model.species_labels"
}
],
"package": "maltsev2009-pacemakercellmodel-nonsteadystate",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "This a model from the article: Synergism of coupled subsarcolemmal Ca2+ clocks and sarcolemmal voltage clocksconfers robust and flexible pacemaker function in a novel pacemaker cell model. It can be used to explore systemsbiology maltsev2009 pacemakercellmodel nonsteadystate model1006230069 dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagemaltsev2009-pacemakercellmodel-nonsteadystate
Created2026-05-17
Updated2026-06-13
systemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother