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Source-faithful physiology lab for Haugh, 2004. Public controls and outputs are mapped to real source symbols for signalling physiology.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_free_h_gh_receptor",
"label": "Initial Free H Gh Receptor",
"maps_to": "physiology_cellml_haugh_2004_haugh2004_model.initial_free_h_gh_receptor",
"description": "Initial value for Free H Gh Receptor. Maps to source symbol `R`. Units: nanomolar. Naming evidence: source metadata names `R` as `free hGH-receptor`.",
"accepted_units": [
"nanomolar"
]
},
{
"name": "initial_internalised_h_gh_receptor",
"label": "Initial Internalised H Gh Receptor",
"maps_to": "physiology_cellml_haugh_2004_haugh2004_model.initial_internalised_h_gh_receptor",
"description": "Initial value for Internalised H Gh Receptor. Maps to source symbol `Ri`. Units: nanomolar. Naming evidence: source metadata names `Ri` as `internalised hGH-receptor`.",
"accepted_units": [
"nanomolar"
]
}
],
"outputs": [
{
"name": "state",
"label": "Selected Source State",
"maps_to": "physiology_cellml_haugh_2004_haugh2004_model.state"
},
{
"name": "summary",
"label": "Simulation Summary",
"maps_to": "physiology_cellml_haugh_2004_haugh2004_model.summary"
},
{
"name": "trajectory",
"label": "Source Trajectory",
"maps_to": "physiology_cellml_haugh_2004_haugh2004_model.trajectory"
},
{
"name": "variable_labels",
"label": "Observable Labels",
"maps_to": "physiology_cellml_haugh_2004_haugh2004_model.variable_labels"
},
{
"name": "free_h_gh_receptor",
"label": "Free H Gh Receptor",
"maps_to": "physiology_cellml_haugh_2004_haugh2004_model.free_h_gh_receptor",
"description": "Free H Gh Receptor. Maps to source symbol `R`. Units: nanomolar. Naming evidence: source metadata names `R` as `free hGH-receptor`."
},
{
"name": "internalised_h_gh_receptor",
"label": "Internalised H Gh Receptor",
"maps_to": "physiology_cellml_haugh_2004_haugh2004_model.internalised_h_gh_receptor",
"description": "Internalised H Gh Receptor. Maps to source symbol `Ri`. Units: nanomolar. Naming evidence: source metadata names `Ri` as `internalised hGH-receptor`."
},
{
"name": "var_1_1_h_gh_receptor_complex",
"label": "Var 1 1 H Gh Receptor Complex",
"maps_to": "physiology_cellml_haugh_2004_haugh2004_model.var_1_1_h_gh_receptor_complex",
"description": "Var 1 1 H Gh Receptor Complex. Maps to source symbol `C`. Units: nanomolar. Naming evidence: source metadata names `C` as `1:1 hGH-receptor complex`."
},
{
"name": "var_1_2_h_gh_receptor_dimer_complex",
"label": "Var 1 2 H Gh Receptor Dimer Complex",
"maps_to": "physiology_cellml_haugh_2004_haugh2004_model.var_1_2_h_gh_receptor_dimer_complex",
"description": "Var 1 2 H Gh Receptor Dimer Complex. Maps to source symbol `D`. Units: nanomolar. Naming evidence: source metadata names `D` as `1:2 hGH-receptor dimer complex`."
},
{
"name": "kappa_e",
"label": "Kappa E",
"maps_to": "physiology_cellml_haugh_2004_haugh2004_model.kappa_e",
"description": "Kappa E. Maps to source symbol `kappaE`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "kdeg",
"label": "Kdeg",
"maps_to": "physiology_cellml_haugh_2004_haugh2004_model.kdeg",
"description": "Kdeg. Maps to source symbol `kdeg`. Units: first_order_rate_constant. Naming evidence: source symbol, component, or units provide a direct public name."
}
]
},
"title": "Haugh2004 - Mathematical Human Growth Hormone H Gh Stimulated Cell Lab",
"models": [
{
"path": "models/core",
"alias": "physiology_cellml_haugh_2004_haugh2004_model",
"parameters": {
"model_path": "data/haugh_2004.cellml",
"integration_step": 0.01
}
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.physiology_cellml_haugh_2004_haugh2004_model_state"
],
"from": "physiology_cellml_haugh_2004_haugh2004_model.state"
},
{
"to": [
"visualisation.physiology_cellml_haugh_2004_haugh2004_model_summary"
],
"from": "physiology_cellml_haugh_2004_haugh2004_model.summary"
},
{
"to": [
"visualisation.physiology_cellml_haugh_2004_haugh2004_model_trajectory"
],
"from": "physiology_cellml_haugh_2004_haugh2004_model.trajectory"
},
{
"to": [
"visualisation.physiology_cellml_haugh_2004_haugh2004_model_variable_labels"
],
"from": "physiology_cellml_haugh_2004_haugh2004_model.variable_labels"
}
],
"package": "haugh2004-mathematical-human-growth-hormone-h-gh-stimulated-cell",
"runtime": {
"duration": 0.01,
"settle_steps": 1,
"initial_inputs": {},
"communication_step": 0.01
},
"version": "1.0.1",
"description": "Source-faithful physiology lab for Haugh, 2004. Public controls and outputs are mapped to real source symbols for signalling physiology.",
"schema_version": "2.0"
}Runtime
Duration0.01
Comms Step0.01
Settle Steps1
Runs
Total0
Completed0
Failed0
Metadata
Packagehaugh2004-mathematical-human-growth-hormone-h-gh-stimulated-cell
Created2026-05-23
Updated2026-06-13
physiologycellmlphysiomefaithfulvisualisationother