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This model of the immune system response to antigen presentation is based on the publication:Eduardo D.Sontag (2017) 'A Dynamic Model of Immune Responses to Antigen Presentation Predicts Different Reg. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_regulatory_cells",
"label": "Initial Regulatory Cells",
"units": "native source value",
"default": 1,
"maps_to": "immunology_sbml_sontag2017_dynamic_model_of_immune_responses_to_biomd0000001030_model.initial_regulatory_cells",
"description": "Initial Regulatory Cells. Sets the initial value of bundled SBML species `Regulatory_cells`."
},
{
"name": "initial_effector_cells",
"label": "Initial Effector Cells",
"units": "native source value",
"default": 1,
"maps_to": "immunology_sbml_sontag2017_dynamic_model_of_immune_responses_to_biomd0000001030_model.initial_effector_cells",
"description": "Initial Effector Cells. Sets the initial value of bundled SBML species `Effector_cells`."
}
],
"outputs": [
{
"name": "antigen_expressing_cells",
"maps_to": "immunology_sbml_sontag2017_dynamic_model_of_immune_responses_to_biomd0000001030_model.antigen_expressing_cells"
},
{
"name": "regulatory_cells",
"maps_to": "immunology_sbml_sontag2017_dynamic_model_of_immune_responses_to_biomd0000001030_model.regulatory_cells"
},
{
"name": "effector_cells",
"maps_to": "immunology_sbml_sontag2017_dynamic_model_of_immune_responses_to_biomd0000001030_model.effector_cells"
},
{
"name": "state",
"maps_to": "immunology_sbml_sontag2017_dynamic_model_of_immune_responses_to_biomd0000001030_model.state"
},
{
"name": "summary",
"maps_to": "immunology_sbml_sontag2017_dynamic_model_of_immune_responses_to_biomd0000001030_model.summary"
},
{
"name": "species_labels",
"maps_to": "immunology_sbml_sontag2017_dynamic_model_of_immune_responses_to_biomd0000001030_model.species_labels"
}
]
},
"title": "Sontag2017 - Dynamic model of immune responses to antigen presentation by tumor or pathogen Lab",
"models": [
{
"path": "models/core",
"alias": "immunology_sbml_sontag2017_dynamic_model_of_immune_responses_to_biomd0000001030_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.immunology_sbml_sontag2017_dynamic_model_of_immune_responses_to_biomd0000001030_model_state"
],
"from": "immunology_sbml_sontag2017_dynamic_model_of_immune_responses_to_biomd0000001030_model.state"
},
{
"to": [
"visualisation.immunology_sbml_sontag2017_dynamic_model_of_immune_responses_to_biomd0000001030_model_summary"
],
"from": "immunology_sbml_sontag2017_dynamic_model_of_immune_responses_to_biomd0000001030_model.summary"
},
{
"to": [
"visualisation.immunology_sbml_sontag2017_dynamic_model_of_immune_responses_to_biomd0000001030_model_species_labels"
],
"from": "immunology_sbml_sontag2017_dynamic_model_of_immune_responses_to_biomd0000001030_model.species_labels"
}
],
"package": "sontag2017-dynamic-model-of-immune-responses-to-antigen",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "This model of the immune system response to antigen presentation is based on the publication:Eduardo D.Sontag (2017) 'A Dynamic Model of Immune Responses to Antigen Presentation Predicts Different Reg. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagesontag2017-dynamic-model-of-immune-responses-to-antigen
Created2026-05-15
Updated2026-06-13
immunologysbmlbiomodels_ebifaithfulcuratedvisualisationother