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This a model from the article: Computational insights on the competing effects of nitric oxide in regulatingapoptosis. Bagci EZ, Vodovotz Y, Billiar TR, Ermentrout B, Bahar I.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_cytc_apaf_1",
"label": "Initial Cytc Apaf 1",
"maps_to": "systemsbiology_sbml_bagci2008_no_apoptosis_modelb_model1006230026_model.initial_cytc_apaf_1",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `CytcApaf_1`."
},
{
"name": "initial_casp9_pro3",
"label": "Initial Casp9 Pro3",
"maps_to": "systemsbiology_sbml_bagci2008_no_apoptosis_modelb_model1006230026_model.initial_casp9_pro3",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Casp9Pro3`."
},
{
"name": "initial_casp9_iap",
"label": "Initial Casp9 Iap",
"maps_to": "systemsbiology_sbml_bagci2008_no_apoptosis_modelb_model1006230026_model.initial_casp9_iap",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Casp9IAP`."
},
{
"name": "initial_casp9",
"label": "Initial Casp9",
"maps_to": "systemsbiology_sbml_bagci2008_no_apoptosis_modelb_model1006230026_model.initial_casp9",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Casp9`."
},
{
"name": "initial_casp8_bid",
"label": "Initial Casp8 Bid",
"maps_to": "systemsbiology_sbml_bagci2008_no_apoptosis_modelb_model1006230026_model.initial_casp8_bid",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Casp8Bid`."
},
{
"name": "initial_casp8",
"label": "Initial Casp8",
"maps_to": "systemsbiology_sbml_bagci2008_no_apoptosis_modelb_model1006230026_model.initial_casp8",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Casp8`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_bagci2008_no_apoptosis_modelb_model1006230026_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_bagci2008_no_apoptosis_modelb_model1006230026_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_bagci2008_no_apoptosis_modelb_model1006230026_model.species_labels"
},
{
"name": "cytc_apaf_1",
"maps_to": "systemsbiology_sbml_bagci2008_no_apoptosis_modelb_model1006230026_model.cytc_apaf_1"
},
{
"name": "casp9_pro3",
"maps_to": "systemsbiology_sbml_bagci2008_no_apoptosis_modelb_model1006230026_model.casp9_pro3"
},
{
"name": "casp9_iap",
"maps_to": "systemsbiology_sbml_bagci2008_no_apoptosis_modelb_model1006230026_model.casp9_iap"
},
{
"name": "casp9",
"maps_to": "systemsbiology_sbml_bagci2008_no_apoptosis_modelb_model1006230026_model.casp9"
},
{
"name": "casp8_bid",
"maps_to": "systemsbiology_sbml_bagci2008_no_apoptosis_modelb_model1006230026_model.casp8_bid"
},
{
"name": "casp8",
"maps_to": "systemsbiology_sbml_bagci2008_no_apoptosis_modelb_model1006230026_model.casp8"
}
]
},
"tags": [
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Bagci2008 No Apoptosis Modelb Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_bagci2008_no_apoptosis_modelb_model1006230026_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_bagci2008_no_apoptosis_modelb_model1006230026_model_state"
],
"from": "systemsbiology_sbml_bagci2008_no_apoptosis_modelb_model1006230026_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_bagci2008_no_apoptosis_modelb_model1006230026_model_summary"
],
"from": "systemsbiology_sbml_bagci2008_no_apoptosis_modelb_model1006230026_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_bagci2008_no_apoptosis_modelb_model1006230026_model_species_labels"
],
"from": "systemsbiology_sbml_bagci2008_no_apoptosis_modelb_model1006230026_model.species_labels"
}
],
"package": "bagci2008-no-apoptosis-modelb",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "This a model from the article: Computational insights on the competing effects of nitric oxide in regulatingapoptosis. Bagci EZ, Vodovotz Y, Billiar TR, Ermentrout B, Bahar I.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagebagci2008-no-apoptosis-modelb
Created2026-05-17
Updated2026-06-13
systemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother