Kholodenko1999 - EGFR signaling Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_egf_egfr",
        "label": "Initial EGF EGFR",
        "maps_to": "signaling_sbml_kholodenko1999_egfr_signaling_biomd0000000048_model.initial_egf_egfr",
        "description": "Initial level of EGF EGFR. Maps to SBML symbol `Ra`; exposed as a traceable initial-condition perturbation."
      },
      {
        "name": "initial_egf_egfr_2",
        "label": "Initial EGF EGFR 2",
        "maps_to": "signaling_sbml_kholodenko1999_egfr_signaling_biomd0000000048_model.initial_egf_egfr_2",
        "description": "Initial level of EGF EGFR 2. Maps to SBML symbol `R2`; exposed as a traceable initial-condition perturbation."
      },
      {
        "name": "initial_egf_egfr_2_grb2_adapter_protein",
        "label": "Initial EGF EGFR 2 Grb2 adapter protein",
        "maps_to": "signaling_sbml_kholodenko1999_egfr_signaling_biomd0000000048_model.initial_egf_egfr_2_grb2_adapter_protein",
        "description": "Initial level of EGF EGFR 2 Grb2 adapter protein. Maps to SBML symbol `RG`; exposed as a traceable initial-condition perturbation."
      }
    ],
    "outputs": [
      {
        "name": "epidermal_growth_factor",
        "label": "Epidermal Growth Factor",
        "maps_to": "signaling_sbml_kholodenko1999_egfr_signaling_biomd0000000048_model.epidermal_growth_factor",
        "description": "Epidermal Growth Factor. Maps to SBML symbol `EGF` and is emitted in native SBML units."
      },
      {
        "name": "egfr",
        "label": "EGFR",
        "maps_to": "signaling_sbml_kholodenko1999_egfr_signaling_biomd0000000048_model.egfr",
        "description": "EGFR. Maps to SBML symbol `R` and is emitted in native SBML units."
      },
      {
        "name": "egf_egfr",
        "label": "EGF EGFR",
        "maps_to": "signaling_sbml_kholodenko1999_egfr_signaling_biomd0000000048_model.egf_egfr",
        "description": "EGF EGFR. Maps to SBML symbol `Ra` and is emitted in native SBML units."
      },
      {
        "name": "state",
        "label": "Observable state",
        "maps_to": "signaling_sbml_kholodenko1999_egfr_signaling_biomd0000000048_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation summary",
        "maps_to": "signaling_sbml_kholodenko1999_egfr_signaling_biomd0000000048_model.summary"
      },
      {
        "name": "species_labels",
        "label": "Observable labels",
        "maps_to": "signaling_sbml_kholodenko1999_egfr_signaling_biomd0000000048_model.species_labels"
      }
    ]
  },
  "tags": [
    "signaling",
    "systems",
    "systems-biology",
    "sbml",
    "faithful",
    "biomodels_ebi",
    "egfr"
  ],
  "title": "Kholodenko1999 - EGFR signaling Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "signaling_sbml_kholodenko1999_egfr_signaling_biomd0000000048_model"
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.signaling_sbml_kholodenko1999_egfr_signaling_biomd0000000048_model_state"
      ],
      "from": "signaling_sbml_kholodenko1999_egfr_signaling_biomd0000000048_model.state"
    },
    {
      "to": [
        "visualisation.signaling_sbml_kholodenko1999_egfr_signaling_biomd0000000048_model_summary"
      ],
      "from": "signaling_sbml_kholodenko1999_egfr_signaling_biomd0000000048_model.summary"
    },
    {
      "to": [
        "visualisation.signaling_sbml_kholodenko1999_egfr_signaling_biomd0000000048_model_species_labels"
      ],
      "from": "signaling_sbml_kholodenko1999_egfr_signaling_biomd0000000048_model.species_labels"
    }
  ],
  "package": "kholodenko1999-egfr-signaling",
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "version": "1.0.0",
  "description": "Clean Biosimulant lab for MAPK/ERK receptor signaling. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.",
  "schema_version": "2.0"
}