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Claret2009 - Predicting phase III overall survival in colorectal cancer This model is described in the article: Model-based prediction of phase III overall survival in colorectal cancer on the basis o. It can be used to explore tumor-related dynamics and compare treatment-response behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "treatment_int_source_parameter",
"label": "Treatment int source parameter",
"units": "native SBML value",
"default": 14,
"maps_to": "oncology_sbml_claret2009_predicting_phase_iii_overall_survival_model1708310001_model.treatment_int_source_parameter",
"description": "Treatment int source parameter. Maps to bundled SBML parameter `treatment_int`."
},
{
"name": "treatment_day_source_parameter",
"label": "Treatment day source parameter",
"units": "native SBML value",
"default": 1,
"maps_to": "oncology_sbml_claret2009_predicting_phase_iii_overall_survival_model1708310001_model.treatment_day_source_parameter",
"description": "Treatment day source parameter. Maps to bundled SBML parameter `treatment_day`."
},
{
"name": "dose_length_source_parameter",
"label": "Dose length source parameter",
"units": "native SBML value",
"default": 0.0625,
"maps_to": "oncology_sbml_claret2009_predicting_phase_iii_overall_survival_model1708310001_model.dose_length_source_parameter",
"description": "Dose length source parameter. Maps to bundled SBML parameter `dose_length`."
},
{
"name": "dose_int2_source_parameter",
"label": "Dose int2 source parameter",
"units": "native SBML value",
"default": 0.5,
"maps_to": "oncology_sbml_claret2009_predicting_phase_iii_overall_survival_model1708310001_model.dose_int2_source_parameter",
"description": "Dose int2 source parameter. Maps to bundled SBML parameter `Dose_int2`."
}
],
"outputs": [
{
"name": "y",
"maps_to": "oncology_sbml_claret2009_predicting_phase_iii_overall_survival_model1708310001_model.y",
"description": "Y observable. Maps to SBML symbol `y`."
},
{
"name": "state",
"maps_to": "oncology_sbml_claret2009_predicting_phase_iii_overall_survival_model1708310001_model.state",
"description": "Full raw SBML observable record for reproducibility and downstream visualisation."
},
{
"name": "summary",
"maps_to": "oncology_sbml_claret2009_predicting_phase_iii_overall_survival_model1708310001_model.summary",
"description": "Change and peak summary across the simulated SBML observables."
},
{
"name": "species_labels",
"maps_to": "oncology_sbml_claret2009_predicting_phase_iii_overall_survival_model1708310001_model.species_labels",
"description": "Mapping from selected raw SBML observable symbols to display labels."
}
]
},
"tags": [
"biomodels_ebi",
"curated",
"drug-response",
"faithful",
"oncology",
"pharmacology",
"physiology",
"sbml",
"systemsbiology",
"tumor-growth"
],
"title": "Claret2009 - Predicting phase III overall survival in colorectal cancer Lab",
"models": [
{
"path": "models/core",
"alias": "oncology_sbml_claret2009_predicting_phase_iii_overall_survival_model1708310001_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.oncology_sbml_claret2009_predicting_phase_iii_overall_survival_model1708310001_model_state"
],
"from": "oncology_sbml_claret2009_predicting_phase_iii_overall_survival_model1708310001_model.state"
},
{
"to": [
"visualisation.oncology_sbml_claret2009_predicting_phase_iii_overall_survival_model1708310001_model_summary"
],
"from": "oncology_sbml_claret2009_predicting_phase_iii_overall_survival_model1708310001_model.summary"
},
{
"to": [
"visualisation.oncology_sbml_claret2009_predicting_phase_iii_overall_survival_model1708310001_model_species_labels"
],
"from": "oncology_sbml_claret2009_predicting_phase_iii_overall_survival_model1708310001_model.species_labels"
}
],
"package": "claret2009-predicting-phase-iii-overall-survival-in-col-5a73f5ec",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "Claret2009 - Predicting phase III overall survival in colorectal cancer This model is described in the article: Model-based prediction of phase III overall survival in colorectal cancer on the basis o. It can be used to explore tumor-related dynamics and compare treatment-response behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packageclaret2009-predicting-phase-iii-overall-survival-in-col-5a73f5ec
Created2026-05-16
Updated2026-06-13
biomodels_ebicurateddrug-responsefaithfuloncologypharmacologyphysiologysbmlsystemsbiologytumor-growthvisualisationother