Dong2014 - Mathematical modeling on helper t cells in a tumor immune system Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_tumor_cells",
        "label": "Initial Tumor Cells",
        "units": "native source value",
        "default": 1,
        "maps_to": "immunology_sbml_dong2014_mathematical_modeling_on_helper_t_cells_biomd0000000783_model.initial_tumor_cells",
        "description": "Initial Tumor Cells. Sets the initial value of bundled SBML species `x_Tumor_Cells`."
      },
      {
        "name": "initial_effector_cells",
        "label": "Initial Effector Cells",
        "units": "native source value",
        "default": 1,
        "maps_to": "immunology_sbml_dong2014_mathematical_modeling_on_helper_t_cells_biomd0000000783_model.initial_effector_cells",
        "description": "Initial Effector Cells. Sets the initial value of bundled SBML species `y_Effector_Cells`."
      },
      {
        "name": "initial_helper_t_cells",
        "label": "Initial Helper T Cells",
        "units": "native source value",
        "default": 1,
        "maps_to": "immunology_sbml_dong2014_mathematical_modeling_on_helper_t_cells_biomd0000000783_model.initial_helper_t_cells",
        "description": "Initial Helper T Cells. Sets the initial value of bundled SBML species `z_Helper_T_Cells`."
      },
      {
        "name": "tumor_growth_rate",
        "label": "Tumor Growth Rate",
        "units": "native source value",
        "default": 1.636,
        "maps_to": "immunology_sbml_dong2014_mathematical_modeling_on_helper_t_cells_biomd0000000783_model.tumor_growth_rate",
        "description": "Tumor Growth Rate. Sets bundled SBML parameter `alpha`."
      },
      {
        "name": "tumor_growth_rate_2",
        "label": "Tumor Growth Rate 2",
        "units": "native source value",
        "default": 0.002,
        "maps_to": "immunology_sbml_dong2014_mathematical_modeling_on_helper_t_cells_biomd0000000783_model.tumor_growth_rate_2",
        "description": "Tumor Growth Rate 2. Sets bundled SBML parameter `beta`."
      },
      {
        "name": "ec_natural_death_rate",
        "label": "Ec Natural Death Rate",
        "units": "native source value",
        "default": 0.3743,
        "maps_to": "immunology_sbml_dong2014_mathematical_modeling_on_helper_t_cells_biomd0000000783_model.ec_natural_death_rate",
        "description": "Ec Natural Death Rate. Sets bundled SBML parameter `delta_1`."
      },
      {
        "name": "htc_natural_death_rate",
        "label": "Htc Natural Death Rate",
        "units": "native source value",
        "default": 0.055,
        "maps_to": "immunology_sbml_dong2014_mathematical_modeling_on_helper_t_cells_biomd0000000783_model.htc_natural_death_rate",
        "description": "Htc Natural Death Rate. Sets bundled SBML parameter `delta_2`."
      }
    ],
    "outputs": [
      {
        "name": "tumor_cells",
        "maps_to": "immunology_sbml_dong2014_mathematical_modeling_on_helper_t_cells_biomd0000000783_model.tumor_cells"
      },
      {
        "name": "effector_cells",
        "maps_to": "immunology_sbml_dong2014_mathematical_modeling_on_helper_t_cells_biomd0000000783_model.effector_cells"
      },
      {
        "name": "helper_t_cells",
        "maps_to": "immunology_sbml_dong2014_mathematical_modeling_on_helper_t_cells_biomd0000000783_model.helper_t_cells"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_dong2014_mathematical_modeling_on_helper_t_cells_biomd0000000783_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_dong2014_mathematical_modeling_on_helper_t_cells_biomd0000000783_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_dong2014_mathematical_modeling_on_helper_t_cells_biomd0000000783_model.species_labels"
      }
    ]
  },
  "title": "Dong2014 - Mathematical modeling on helper t cells in a tumor immune system Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "immunology_sbml_dong2014_mathematical_modeling_on_helper_t_cells_biomd0000000783_model"
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_dong2014_mathematical_modeling_on_helper_t_cells_biomd0000000783_model_state"
      ],
      "from": "immunology_sbml_dong2014_mathematical_modeling_on_helper_t_cells_biomd0000000783_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_dong2014_mathematical_modeling_on_helper_t_cells_biomd0000000783_model_summary"
      ],
      "from": "immunology_sbml_dong2014_mathematical_modeling_on_helper_t_cells_biomd0000000783_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_dong2014_mathematical_modeling_on_helper_t_cells_biomd0000000783_model_species_labels"
      ],
      "from": "immunology_sbml_dong2014_mathematical_modeling_on_helper_t_cells_biomd0000000783_model.species_labels"
    }
  ],
  "package": "dong2014-mathematical-modeling-on-helper-t-cells-in",
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "version": "1.0.0",
  "description": "This model gives a mathematical description of the interactions between tumor cells, cytotoxic T lymphocytes and helper T cells (HTCs) within the tumor microenvironment, with emphasis on the role play. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
  "schema_version": "2.0"
}