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Source-faithful physiology lab for Perelson, Neumann, Markowitz, Leonard, Ho, 1996. Public controls and outputs are mapped to real source symbols for source-model physiology.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_density_state_vi",
"label": "Initial Density State Vi (source VI)",
"maps_to": "physiology_cellml_perelson_neumann_markowitz_leonard_ho_1996_perelsonneumannmarkowitzleonardho1996_model.initial_density_state_vi",
"description": "Initial value for Density State Vi (source VI). Maps to source symbol `VI`. Units: per_ml. Naming evidence: density-like units identify a concentration or density state.",
"accepted_units": [
"per_ml"
]
},
{
"name": "initial_vni",
"label": "Initial Vni",
"maps_to": "physiology_cellml_perelson_neumann_markowitz_leonard_ho_1996_perelsonneumannmarkowitzleonardho1996_model.initial_vni",
"description": "Initial value for Vni. Maps to source symbol `VNI`. Units: per_ml. Naming evidence: source symbol, component, or units provide a direct public name.",
"accepted_units": [
"per_ml"
]
}
],
"outputs": [
{
"name": "state",
"label": "Selected Source State",
"maps_to": "physiology_cellml_perelson_neumann_markowitz_leonard_ho_1996_perelsonneumannmarkowitzleonardho1996_model.state"
},
{
"name": "summary",
"label": "Simulation Summary",
"maps_to": "physiology_cellml_perelson_neumann_markowitz_leonard_ho_1996_perelsonneumannmarkowitzleonardho1996_model.summary"
},
{
"name": "trajectory",
"label": "Source Trajectory",
"maps_to": "physiology_cellml_perelson_neumann_markowitz_leonard_ho_1996_perelsonneumannmarkowitzleonardho1996_model.trajectory"
},
{
"name": "variable_labels",
"label": "Observable Labels",
"maps_to": "physiology_cellml_perelson_neumann_markowitz_leonard_ho_1996_perelsonneumannmarkowitzleonardho1996_model.variable_labels"
},
{
"name": "density_state_vi",
"label": "Density State Vi (source VI)",
"maps_to": "physiology_cellml_perelson_neumann_markowitz_leonard_ho_1996_perelsonneumannmarkowitzleonardho1996_model.density_state_vi",
"description": "Density State Vi (source VI). Maps to source symbol `VI`. Units: per_ml. Naming evidence: density-like units identify a concentration or density state."
},
{
"name": "vni",
"label": "Vni",
"maps_to": "physiology_cellml_perelson_neumann_markowitz_leonard_ho_1996_perelsonneumannmarkowitzleonardho1996_model.vni",
"description": "Vni. Maps to source symbol `VNI`. Units: per_ml. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "t_star",
"label": "T Star",
"maps_to": "physiology_cellml_perelson_neumann_markowitz_leonard_ho_1996_perelsonneumannmarkowitzleonardho1996_model.t_star",
"description": "T Star. Maps to source symbol `T_star`. Units: per_ml. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "delta",
"label": "Delta",
"maps_to": "physiology_cellml_perelson_neumann_markowitz_leonard_ho_1996_perelsonneumannmarkowitzleonardho1996_model.delta",
"description": "Delta. Maps to source symbol `delta`. Units: first_order_rate_constant. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "density_state_state",
"label": "Density State State (source T)",
"maps_to": "physiology_cellml_perelson_neumann_markowitz_leonard_ho_1996_perelsonneumannmarkowitzleonardho1996_model.density_state_state",
"description": "Density State State (source T). Maps to source symbol `T`. Units: per_ml. Naming evidence: density-like units identify a concentration or density state."
},
{
"name": "viral_quantity_v",
"label": "Viral Quantity V (source V)",
"maps_to": "physiology_cellml_perelson_neumann_markowitz_leonard_ho_1996_perelsonneumannmarkowitzleonardho1996_model.viral_quantity_v",
"description": "Viral Quantity V (source V). Maps to source symbol `V`. Units: per_ml. Naming evidence: viral/infection context supports a conservative viral quantity label."
}
]
},
"title": "Perelson1996 - Hiv 1 Dynamics Vivo Virion Clearance Rate Infected Cell Lab",
"models": [
{
"path": "models/core",
"alias": "physiology_cellml_perelson_neumann_markowitz_leonard_ho_1996_perelsonneumannmarkowitzleonardho1996_model",
"parameters": {
"model_path": "data/perelson_neumann_markowitz_leonard_ho_1996.cellml",
"integration_step": 0.01
}
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.physiology_cellml_perelson_neumann_markowitz_leonard_ho_1996_perelsonneumannmarkowitzleonardho1996_model_state"
],
"from": "physiology_cellml_perelson_neumann_markowitz_leonard_ho_1996_perelsonneumannmarkowitzleonardho1996_model.state"
},
{
"to": [
"visualisation.physiology_cellml_perelson_neumann_markowitz_leonard_ho_1996_perelsonneumannmarkowitzleonardho1996_model_summary"
],
"from": "physiology_cellml_perelson_neumann_markowitz_leonard_ho_1996_perelsonneumannmarkowitzleonardho1996_model.summary"
},
{
"to": [
"visualisation.physiology_cellml_perelson_neumann_markowitz_leonard_ho_1996_perelsonneumannmarkowitzleonardho1996_model_trajectory"
],
"from": "physiology_cellml_perelson_neumann_markowitz_leonard_ho_1996_perelsonneumannmarkowitzleonardho1996_model.trajectory"
},
{
"to": [
"visualisation.physiology_cellml_perelson_neumann_markowitz_leonard_ho_1996_perelsonneumannmarkowitzleonardho1996_model_variable_labels"
],
"from": "physiology_cellml_perelson_neumann_markowitz_leonard_ho_1996_perelsonneumannmarkowitzleonardho1996_model.variable_labels"
}
],
"package": "perelson1996-hiv-1-dynamics-vivo-virion-clearance-rate-5cb40f9e",
"runtime": {
"duration": 0.01,
"settle_steps": 1,
"initial_inputs": {},
"communication_step": 0.01
},
"version": "1.0.0",
"description": "Source-faithful physiology lab for Perelson, Neumann, Markowitz, Leonard, Ho, 1996. Public controls and outputs are mapped to real source symbols for source-model physiology.",
"schema_version": "2.0"
}Runtime
Duration0.01
Comms Step0.01
Settle Steps1
Runs
Total0
Completed0
Failed0
Metadata
Packageperelson1996-hiv-1-dynamics-vivo-virion-clearance-rate-5cb40f9e
Created2026-05-23
Updated2026-06-13
physiologycellmlphysiomefaithfulvisualisationother