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This a model from the article: A quantitative model of sleep-wake dynamics based on the physiology of thebrainstem ascending arousal system. It can be used to explore systemsbiology phillips2007 ascendingarousalsystem sleepwakedyn BioModels0000000917 dynamics and compare simulation behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_somnogen_level_h",
"label": "Initial Somnogen Level H",
"maps_to": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model.initial_somnogen_level_h",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Somnogen_level_H`."
},
{
"name": "initial_ventrolateral_preopticarea_vlpo_voltage",
"label": "Initial Ventrolateral Preopticarea Vlpo Voltage",
"maps_to": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model.initial_ventrolateral_preopticarea_vlpo_voltage",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Ventrolateral_preopticarea__VLPO__voltage`."
},
{
"name": "initial_monoaminergic_ma_voltage",
"label": "Initial Monoaminergic Ma Voltage",
"maps_to": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model.initial_monoaminergic_ma_voltage",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Monoaminergic__MA__voltage`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model.species_labels"
},
{
"name": "somnogen_level_h",
"maps_to": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model.somnogen_level_h"
},
{
"name": "ventrolateral_preopticarea_vlpo_voltage",
"maps_to": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model.ventrolateral_preopticarea_vlpo_voltage"
},
{
"name": "monoaminergic_ma_voltage",
"maps_to": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model.monoaminergic_ma_voltage"
}
]
},
"tags": [
"physiology",
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Phillips2007 Ascendingarousalsystem Sleepwakedynamics Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model_state"
],
"from": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model_summary"
],
"from": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model_species_labels"
],
"from": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model.species_labels"
}
],
"package": "phillips2007-ascendingarousalsystem-sleepwakedynamics",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "This a model from the article: A quantitative model of sleep-wake dynamics based on the physiology of thebrainstem ascending arousal system. It can be used to explore systemsbiology phillips2007 ascendingarousalsystem sleepwakedyn BioModels0000000917 dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagephillips2007-ascendingarousalsystem-sleepwakedynamics
Created2026-05-17
Updated2026-06-13
physiologysystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother