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The paper describes a model of effect of cellular de-differentiation on the dynamics and evolution of tissue and tumor cells. Created by COPASI 4.25 (Build 207) This model is described in the article:.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_stem_like_cells",
"label": "Stem-Like Cells",
"units": "native SBML value",
"default": 1,
"maps_to": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model.initial_stem_like_cells",
"description": "Initial Stem-Like Cells. Sets the initial value of bundled SBML symbol `S`."
},
{
"name": "initial_transit_amplifying_cells",
"label": "Transit-Amplifying Cells",
"units": "native SBML value",
"default": 0,
"maps_to": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model.initial_transit_amplifying_cells",
"description": "Initial Transit-Amplifying Cells. Sets the initial value of bundled SBML symbol `T`."
},
{
"name": "initial_differentiated_cells",
"label": "Differentiated Cells",
"units": "native SBML value",
"default": 0,
"maps_to": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model.initial_differentiated_cells",
"description": "Initial Differentiated Cells. Sets the initial value of bundled SBML symbol `D`."
}
],
"outputs": [
{
"name": "stem_like_cells",
"maps_to": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model.stem_like_cells",
"description": "Stem-Like Cells observable. Maps to SBML symbol `S`."
},
{
"name": "transit_amplifying_cells",
"maps_to": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model.transit_amplifying_cells",
"description": "Transit-Amplifying Cells observable. Maps to SBML symbol `T`."
},
{
"name": "differentiated_cells",
"maps_to": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model.differentiated_cells",
"description": "Differentiated Cells observable. Maps to SBML symbol `D`."
},
{
"name": "state",
"maps_to": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model.state",
"description": "Full raw SBML observable record for reproducibility and downstream visualisation."
},
{
"name": "summary",
"maps_to": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model.summary",
"description": "Change and peak summary across the simulated SBML observables."
},
{
"name": "species_labels",
"maps_to": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model.species_labels",
"description": "Mapping from selected raw SBML observable symbols to display labels."
}
]
},
"tags": [
"biomodels_ebi",
"curated",
"faithful",
"oncology",
"physiology",
"sbml",
"systemsbiology",
"tumor-growth"
],
"title": "Wodarz2018/2 - model with transit amplifying cells Lab",
"models": [
{
"path": "models/core",
"alias": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model_state"
],
"from": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model.state"
},
{
"to": [
"visualisation.oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model_summary"
],
"from": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model.summary"
},
{
"to": [
"visualisation.oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model_species_labels"
],
"from": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model.species_labels"
}
],
"package": "wodarz2018-2-with-transit-amplifying-cells",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "The paper describes a model of effect of cellular de-differentiation on the dynamics and evolution of tissue and tumor cells. Created by COPASI 4.25 (Build 207) This model is described in the article:.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagewodarz2018-2-with-transit-amplifying-cells
Created2026-05-16
Updated2026-06-13
biomodels_ebicuratedfaithfuloncologyphysiologysbmlsystemsbiologytumor-growthvisualisationother