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Proctor2013 - Effect of Aβ immunisationin Alzheimer's disease (stochastic version) Extension of a previously publishedstochastic model (designed to examine some of the key pathwaysinvolved in the aggr. It can be used to explore systemsbiology proctor2013 effect of a immunisation dynamics and compare simulation behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_model_state_atp",
"label": "Initial Model State ATP",
"maps_to": "systemsbiology_sbml_proctor2013_effect_of_a_immunisation_in_alzheime_biomd0000000634_model.initial_model_state_atp",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `ATP`."
},
{
"name": "initial_model_state_adp",
"label": "Initial Model State ADP",
"maps_to": "systemsbiology_sbml_proctor2013_effect_of_a_immunisation_in_alzheime_biomd0000000634_model.initial_model_state_adp",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `ADP`."
},
{
"name": "initial_p53_mrna",
"label": "Initial P53 MRNA",
"maps_to": "systemsbiology_sbml_proctor2013_effect_of_a_immunisation_in_alzheime_biomd0000000634_model.initial_p53_mrna",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `p53_mRNA`."
},
{
"name": "initial_mdm2_mrna",
"label": "Initial Mdm2 MRNA",
"maps_to": "systemsbiology_sbml_proctor2013_effect_of_a_immunisation_in_alzheime_biomd0000000634_model.initial_mdm2_mrna",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Mdm2_mRNA`."
},
{
"name": "initial_model_state_ub",
"label": "Initial Model State Ub",
"maps_to": "systemsbiology_sbml_proctor2013_effect_of_a_immunisation_in_alzheime_biomd0000000634_model.initial_model_state_ub",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Ub`."
},
{
"name": "initial_model_state_amp",
"label": "Initial Model State AMP",
"maps_to": "systemsbiology_sbml_proctor2013_effect_of_a_immunisation_in_alzheime_biomd0000000634_model.initial_model_state_amp",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `AMP`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_proctor2013_effect_of_a_immunisation_in_alzheime_biomd0000000634_model.state"
},
{
"name": "summary",
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},
{
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{
"name": "atp",
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},
{
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},
{
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},
{
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"maps_to": "systemsbiology_sbml_proctor2013_effect_of_a_immunisation_in_alzheime_biomd0000000634_model.mdm2_mrna"
},
{
"name": "model_state_ub",
"maps_to": "systemsbiology_sbml_proctor2013_effect_of_a_immunisation_in_alzheime_biomd0000000634_model.model_state_ub"
},
{
"name": "amp",
"maps_to": "systemsbiology_sbml_proctor2013_effect_of_a_immunisation_in_alzheime_biomd0000000634_model.amp"
}
]
},
"tags": [
"neuroscience",
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Proctor2013 Effect Of A Immunisation In Alzheimer S Disease 2 Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_proctor2013_effect_of_a_immunisation_in_alzheime_biomd0000000634_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
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},
{
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],
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},
{
"to": [
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],
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}
],
"package": "proctor2013-effect-of-a-immunisation-in-alzheimer-s-disease-2",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "Proctor2013 - Effect of Aβ immunisationin Alzheimer's disease (stochastic version) Extension of a previously publishedstochastic model (designed to examine some of the key pathwaysinvolved in the aggr. It can be used to explore systemsbiology proctor2013 effect of a immunisation dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packageproctor2013-effect-of-a-immunisation-in-alzheimer-s-disease-2
Created2026-05-17
Updated2026-06-13
neurosciencesystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother