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The model reproduces the same amplitude antiphase calcium oscillations of coupled cells depicted in Figure 5B of the publication. This model was successfully tested on Jarnac and MathSBML.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_receptor_fraction_cell1",
"label": "Initial Receptor Fraction Cell1",
"maps_to": "systemsbiology_sbml_bindschadler2001_coupled_ca_oscillators_biomd0000000058_model.initial_receptor_fraction_cell1",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `h1`."
},
{
"name": "initial_calcium_ion_cell1",
"label": "Initial Calcium Ion Cell1",
"maps_to": "systemsbiology_sbml_bindschadler2001_coupled_ca_oscillators_biomd0000000058_model.initial_calcium_ion_cell1",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `c1`."
},
{
"name": "initial_receptor_fraction_cell2",
"label": "Initial Receptor Fraction Cell2",
"maps_to": "systemsbiology_sbml_bindschadler2001_coupled_ca_oscillators_biomd0000000058_model.initial_receptor_fraction_cell2",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `h2`."
},
{
"name": "initial_calcium_ion_cell2",
"label": "Initial Calcium Ion Cell2",
"maps_to": "systemsbiology_sbml_bindschadler2001_coupled_ca_oscillators_biomd0000000058_model.initial_calcium_ion_cell2",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `c2`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_bindschadler2001_coupled_ca_oscillators_biomd0000000058_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_bindschadler2001_coupled_ca_oscillators_biomd0000000058_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_bindschadler2001_coupled_ca_oscillators_biomd0000000058_model.species_labels"
},
{
"name": "receptor_fraction_cell1",
"maps_to": "systemsbiology_sbml_bindschadler2001_coupled_ca_oscillators_biomd0000000058_model.receptor_fraction_cell1"
},
{
"name": "calcium_ion_cell1",
"maps_to": "systemsbiology_sbml_bindschadler2001_coupled_ca_oscillators_biomd0000000058_model.calcium_ion_cell1"
},
{
"name": "receptor_fraction_cell2",
"maps_to": "systemsbiology_sbml_bindschadler2001_coupled_ca_oscillators_biomd0000000058_model.receptor_fraction_cell2"
},
{
"name": "calcium_ion_cell2",
"maps_to": "systemsbiology_sbml_bindschadler2001_coupled_ca_oscillators_biomd0000000058_model.calcium_ion_cell2"
}
]
},
"tags": [
"generegulation",
"physiology",
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Bindschadler2001 Coupled Ca Oscillators Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_bindschadler2001_coupled_ca_oscillators_biomd0000000058_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_bindschadler2001_coupled_ca_oscillators_biomd0000000058_model_state"
],
"from": "systemsbiology_sbml_bindschadler2001_coupled_ca_oscillators_biomd0000000058_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_bindschadler2001_coupled_ca_oscillators_biomd0000000058_model_summary"
],
"from": "systemsbiology_sbml_bindschadler2001_coupled_ca_oscillators_biomd0000000058_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_bindschadler2001_coupled_ca_oscillators_biomd0000000058_model_species_labels"
],
"from": "systemsbiology_sbml_bindschadler2001_coupled_ca_oscillators_biomd0000000058_model.species_labels"
}
],
"package": "bindschadler2001-coupled-ca-oscillators",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "The model reproduces the same amplitude antiphase calcium oscillations of coupled cells depicted in Figure 5B of the publication. This model was successfully tested on Jarnac and MathSBML.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagebindschadler2001-coupled-ca-oscillators
Created2026-05-17
Updated2026-06-13
generegulationphysiologysystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother