Lipniacki2004 - Mathematical model of NFKB regulatory module Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_tumor_necrosis_factor_receptor_level",
        "label": "Initial tumor necrosis factor receptor level",
        "maps_to": "signaling_sbml_lipniacki2004_mathematical_model_of_nfkb_regulat_biomd0000000786_model.initial_tumor_necrosis_factor_receptor_level",
        "description": "Tumor necrosis factor receptor source parameter. Maps to SBML symbol `TNF_R` and preserves the bundled default."
      },
      {
        "name": "initial_tnf_receptor_level",
        "label": "TNF receptor level (legacy)",
        "maps_to": "signaling_sbml_lipniacki2004_mathematical_model_of_nfkb_regulat_biomd0000000786_model.initial_tnf_receptor_level",
        "description": "Legacy alias for tumor necrosis factor receptor level. Maps to SBML symbol `TNF_R` and preserves the bundled default."
      },
      {
        "name": "initial_tumor_necrosis_factor_level",
        "label": "Initial tumor necrosis factor level",
        "maps_to": "signaling_sbml_lipniacki2004_mathematical_model_of_nfkb_regulat_biomd0000000786_model.initial_tumor_necrosis_factor_level",
        "description": "Initial tumor necrosis factor level. Maps to SBML symbol `TNF`; exposed as a traceable initial-condition perturbation."
      },
      {
        "name": "initial_tnf",
        "label": "Initial TNF level (legacy)",
        "maps_to": "signaling_sbml_lipniacki2004_mathematical_model_of_nfkb_regulat_biomd0000000786_model.initial_tnf",
        "description": "Legacy alias for initial tumor necrosis factor level. Maps to SBML symbol `TNF`; exposed as a traceable initial-condition perturbation."
      }
    ],
    "outputs": [
      {
        "name": "inhibitor_kappa_b_kinase_active",
        "label": "Active inhibitor kappa B kinase",
        "maps_to": "signaling_sbml_lipniacki2004_mathematical_model_of_nfkb_regulat_biomd0000000786_model.inhibitor_kappa_b_kinase_active",
        "description": "Active inhibitor kappa B kinase. Maps to SBML symbol `IKK_active` and is emitted in native SBML units."
      },
      {
        "name": "active_kinase_inhibitor_kappa_b_complex",
        "label": "Active kinase - inhibitor kappa B complex",
        "maps_to": "signaling_sbml_lipniacki2004_mathematical_model_of_nfkb_regulat_biomd0000000786_model.active_kinase_inhibitor_kappa_b_complex",
        "description": "Active inhibitor kappa B kinase bound to inhibitor kappa B. Maps to SBML symbol `IKKactive_IkB` and is emitted in native SBML units."
      },
      {
        "name": "active_kinase_inhibitor_kappa_b_nuclear_factor_kappa_b_complex",
        "label": "Active kinase - inhibitor kappa B - nuclear factor kappa B complex",
        "maps_to": "signaling_sbml_lipniacki2004_mathematical_model_of_nfkb_regulat_biomd0000000786_model.active_kinase_inhibitor_kappa_b_nuclear_factor_kappa_b_complex",
        "description": "Active inhibitor kappa B kinase bound to the inhibitor kappa B and nuclear factor kappa B complex. Maps to SBML symbol `IKKactive_IkB_NFKB` and is emitted in native SBML units."
      },
      {
        "name": "ikk_active",
        "label": "Active IKK (legacy)",
        "maps_to": "signaling_sbml_lipniacki2004_mathematical_model_of_nfkb_regulat_biomd0000000786_model.ikk_active",
        "description": "Legacy alias for active inhibitor kappa B kinase. Maps to SBML symbol `IKK_active` and is emitted in native SBML units."
      },
      {
        "name": "ikkactive_ik_b",
        "label": "Ikkactive Ik B",
        "maps_to": "signaling_sbml_lipniacki2004_mathematical_model_of_nfkb_regulat_biomd0000000786_model.ikkactive_ik_b",
        "description": "Ikkactive Ik B. Maps to SBML symbol `IKKactive_IkB` and is emitted in native SBML units."
      },
      {
        "name": "ikkactive_ik_b_nfkb",
        "label": "Ikkactive Ik B NF-kB",
        "maps_to": "signaling_sbml_lipniacki2004_mathematical_model_of_nfkb_regulat_biomd0000000786_model.ikkactive_ik_b_nfkb",
        "description": "Ikkactive Ik B NF-kB. Maps to SBML symbol `IKKactive_IkB_NFKB` and is emitted in native SBML units."
      },
      {
        "name": "state",
        "label": "Observable state",
        "maps_to": "signaling_sbml_lipniacki2004_mathematical_model_of_nfkb_regulat_biomd0000000786_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation summary",
        "maps_to": "signaling_sbml_lipniacki2004_mathematical_model_of_nfkb_regulat_biomd0000000786_model.summary"
      },
      {
        "name": "species_labels",
        "label": "Observable labels",
        "maps_to": "signaling_sbml_lipniacki2004_mathematical_model_of_nfkb_regulat_biomd0000000786_model.species_labels"
      }
    ]
  },
  "tags": [
    "signaling",
    "systems",
    "systems-biology",
    "sbml",
    "faithful",
    "biomodels_ebi",
    "nfkb",
    "tnf-signaling"
  ],
  "title": "Lipniacki2004 - Mathematical model of NFKB regulatory module Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "signaling_sbml_lipniacki2004_mathematical_model_of_nfkb_regulat_biomd0000000786_model"
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.signaling_sbml_lipniacki2004_mathematical_model_of_nfkb_regulat_biomd0000000786_model_state"
      ],
      "from": "signaling_sbml_lipniacki2004_mathematical_model_of_nfkb_regulat_biomd0000000786_model.state"
    },
    {
      "to": [
        "visualisation.signaling_sbml_lipniacki2004_mathematical_model_of_nfkb_regulat_biomd0000000786_model_summary"
      ],
      "from": "signaling_sbml_lipniacki2004_mathematical_model_of_nfkb_regulat_biomd0000000786_model.summary"
    },
    {
      "to": [
        "visualisation.signaling_sbml_lipniacki2004_mathematical_model_of_nfkb_regulat_biomd0000000786_model_species_labels"
      ],
      "from": "signaling_sbml_lipniacki2004_mathematical_model_of_nfkb_regulat_biomd0000000786_model.species_labels"
    }
  ],
  "package": "lipniacki2004-mathematical-model-of-nfkb-regulat",
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "version": "1.0.0",
  "description": "Clean Biosimulant lab for NF-kB pathway signaling. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.",
  "schema_version": "2.0"
}