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Source-faithful physiology lab for Neumann, Lam, Dahari, Gretch, Wiley, Layden, Perelson, 1998. Public controls and outputs are mapped to real source symbols for source-model physiology.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_infected_cells_i",
"label": "Initial Infected Cells I",
"maps_to": "physiology_cellml_neumann_lam_dahari_gretch_wiley_layden_perelson_neumannlamdaharigretchwileylaydenperelson1998_model.initial_infected_cells_i",
"description": "Initial value for Infected Cells I. Maps to source symbol `I`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name.",
"accepted_units": [
"dimensionless"
]
},
{
"name": "initial_target_cells_t",
"label": "Initial Target Cells T",
"maps_to": "physiology_cellml_neumann_lam_dahari_gretch_wiley_layden_perelson_neumannlamdaharigretchwileylaydenperelson1998_model.initial_target_cells_t",
"description": "Initial value for Target Cells T. Maps to source symbol `T`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name.",
"accepted_units": [
"dimensionless"
]
}
],
"outputs": [
{
"name": "state",
"label": "Selected Source State",
"maps_to": "physiology_cellml_neumann_lam_dahari_gretch_wiley_layden_perelson_neumannlamdaharigretchwileylaydenperelson1998_model.state"
},
{
"name": "summary",
"label": "Simulation Summary",
"maps_to": "physiology_cellml_neumann_lam_dahari_gretch_wiley_layden_perelson_neumannlamdaharigretchwileylaydenperelson1998_model.summary"
},
{
"name": "trajectory",
"label": "Source Trajectory",
"maps_to": "physiology_cellml_neumann_lam_dahari_gretch_wiley_layden_perelson_neumannlamdaharigretchwileylaydenperelson1998_model.trajectory"
},
{
"name": "variable_labels",
"label": "Observable Labels",
"maps_to": "physiology_cellml_neumann_lam_dahari_gretch_wiley_layden_perelson_neumannlamdaharigretchwileylaydenperelson1998_model.variable_labels"
},
{
"name": "infected_cells_i",
"label": "Infected Cells I",
"maps_to": "physiology_cellml_neumann_lam_dahari_gretch_wiley_layden_perelson_neumannlamdaharigretchwileylaydenperelson1998_model.infected_cells_i",
"description": "Infected Cells I. Maps to source symbol `I`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "target_cells_t",
"label": "Target Cells T",
"maps_to": "physiology_cellml_neumann_lam_dahari_gretch_wiley_layden_perelson_neumannlamdaharigretchwileylaydenperelson1998_model.target_cells_t",
"description": "Target Cells T. Maps to source symbol `T`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "viral_quantity_v",
"label": "Viral Quantity V (source V)",
"maps_to": "physiology_cellml_neumann_lam_dahari_gretch_wiley_layden_perelson_neumannlamdaharigretchwileylaydenperelson1998_model.viral_quantity_v",
"description": "Viral Quantity V (source V). Maps to source symbol `V`. Units: dimensionless. Naming evidence: viral/infection context supports a conservative viral quantity label."
},
{
"name": "beta",
"label": "Beta",
"maps_to": "physiology_cellml_neumann_lam_dahari_gretch_wiley_layden_perelson_neumannlamdaharigretchwileylaydenperelson1998_model.beta",
"description": "Beta. Maps to source symbol `beta`. Units: first_order_rate_constant. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "delta",
"label": "Delta",
"maps_to": "physiology_cellml_neumann_lam_dahari_gretch_wiley_layden_perelson_neumannlamdaharigretchwileylaydenperelson1998_model.delta",
"description": "Delta. Maps to source symbol `delta`. Units: first_order_rate_constant. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "epsilon",
"label": "Epsilon",
"maps_to": "physiology_cellml_neumann_lam_dahari_gretch_wiley_layden_perelson_neumannlamdaharigretchwileylaydenperelson1998_model.epsilon",
"description": "Epsilon. Maps to source symbol `epsilon`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
}
]
},
"title": "Neumann1998 - Mathematical Hepatitis C Viral Dynamics Vivo Antiviral Lab",
"models": [
{
"path": "models/core",
"alias": "physiology_cellml_neumann_lam_dahari_gretch_wiley_layden_perelson_neumannlamdaharigretchwileylaydenperelson1998_model",
"parameters": {
"model_path": "data/neumann_lam_dahari_gretch_wiley_layden_perelson_1998.cellml",
"integration_step": 0.01
}
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.physiology_cellml_neumann_lam_dahari_gretch_wiley_layden_perelson_neumannlamdaharigretchwileylaydenperelson1998_model_state"
],
"from": "physiology_cellml_neumann_lam_dahari_gretch_wiley_layden_perelson_neumannlamdaharigretchwileylaydenperelson1998_model.state"
},
{
"to": [
"visualisation.physiology_cellml_neumann_lam_dahari_gretch_wiley_layden_perelson_neumannlamdaharigretchwileylaydenperelson1998_model_summary"
],
"from": "physiology_cellml_neumann_lam_dahari_gretch_wiley_layden_perelson_neumannlamdaharigretchwileylaydenperelson1998_model.summary"
},
{
"to": [
"visualisation.physiology_cellml_neumann_lam_dahari_gretch_wiley_layden_perelson_neumannlamdaharigretchwileylaydenperelson1998_model_trajectory"
],
"from": "physiology_cellml_neumann_lam_dahari_gretch_wiley_layden_perelson_neumannlamdaharigretchwileylaydenperelson1998_model.trajectory"
},
{
"to": [
"visualisation.physiology_cellml_neumann_lam_dahari_gretch_wiley_layden_perelson_neumannlamdaharigretchwileylaydenperelson1998_model_variable_labels"
],
"from": "physiology_cellml_neumann_lam_dahari_gretch_wiley_layden_perelson_neumannlamdaharigretchwileylaydenperelson1998_model.variable_labels"
}
],
"package": "neumann1998-mathematical-hepatitis-c-viral-dynamics-viv-6e15cb21",
"runtime": {
"duration": 0.01,
"settle_steps": 1,
"initial_inputs": {},
"communication_step": 0.01
},
"version": "1.0.0",
"description": "Source-faithful physiology lab for Neumann, Lam, Dahari, Gretch, Wiley, Layden, Perelson, 1998. Public controls and outputs are mapped to real source symbols for source-model physiology.",
"schema_version": "2.0"
}Runtime
Duration0.01
Comms Step0.01
Settle Steps1
Runs
Total0
Completed0
Failed0
Metadata
Packageneumann1998-mathematical-hepatitis-c-viral-dynamics-viv-6e15cb21
Created2026-05-23
Updated2026-06-13
physiologycellmlphysiomefaithfulvisualisationother