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This a model from the article: Mathematical modelling of calcium wave propagation in mammalian airwayepithelium: evidence for regenerative ATP release. It can be used to explore systemsbiology warren2009 calciumwavepropagation model1006230018 dynamics and compare simulation behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_volume_ca_i",
"label": "Initial Volume Ca I",
"maps_to": "systemsbiology_sbml_warren2009_calciumwavepropagation_model1006230018_model.initial_volume_ca_i",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `volumeCa_i`."
},
{
"name": "initial_volume_ca_er",
"label": "Initial Volume Ca Er",
"maps_to": "systemsbiology_sbml_warren2009_calciumwavepropagation_model1006230018_model.initial_volume_ca_er",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `volumeCa_er`."
},
{
"name": "initial_volume_iip3",
"label": "Initial Volume Iip3",
"maps_to": "systemsbiology_sbml_warren2009_calciumwavepropagation_model1006230018_model.initial_volume_iip3",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `volume_iIP3`."
},
{
"name": "initial_pip2",
"label": "Initial Pip2",
"maps_to": "systemsbiology_sbml_warren2009_calciumwavepropagation_model1006230018_model.initial_pip2",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `PIP2`."
},
{
"name": "initial_model_state_i2",
"label": "Initial Model State I2",
"maps_to": "systemsbiology_sbml_warren2009_calciumwavepropagation_model1006230018_model.initial_model_state_i2",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `I2`."
},
{
"name": "initial_model_state_i1",
"label": "Initial Model State I1",
"maps_to": "systemsbiology_sbml_warren2009_calciumwavepropagation_model1006230018_model.initial_model_state_i1",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `I1`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_warren2009_calciumwavepropagation_model1006230018_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_warren2009_calciumwavepropagation_model1006230018_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_warren2009_calciumwavepropagation_model1006230018_model.species_labels"
},
{
"name": "volume_ca_i",
"maps_to": "systemsbiology_sbml_warren2009_calciumwavepropagation_model1006230018_model.volume_ca_i"
},
{
"name": "volume_ca_er",
"maps_to": "systemsbiology_sbml_warren2009_calciumwavepropagation_model1006230018_model.volume_ca_er"
},
{
"name": "volume_iip3",
"maps_to": "systemsbiology_sbml_warren2009_calciumwavepropagation_model1006230018_model.volume_iip3"
},
{
"name": "pip2",
"maps_to": "systemsbiology_sbml_warren2009_calciumwavepropagation_model1006230018_model.pip2"
},
{
"name": "model_state_i2",
"maps_to": "systemsbiology_sbml_warren2009_calciumwavepropagation_model1006230018_model.model_state_i2"
},
{
"name": "model_state_i1",
"maps_to": "systemsbiology_sbml_warren2009_calciumwavepropagation_model1006230018_model.model_state_i1"
}
]
},
"tags": [
"generegulation",
"metabolism",
"physiology",
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Warren2009 Calciumwavepropagation Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_warren2009_calciumwavepropagation_model1006230018_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_warren2009_calciumwavepropagation_model1006230018_model_state"
],
"from": "systemsbiology_sbml_warren2009_calciumwavepropagation_model1006230018_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_warren2009_calciumwavepropagation_model1006230018_model_summary"
],
"from": "systemsbiology_sbml_warren2009_calciumwavepropagation_model1006230018_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_warren2009_calciumwavepropagation_model1006230018_model_species_labels"
],
"from": "systemsbiology_sbml_warren2009_calciumwavepropagation_model1006230018_model.species_labels"
}
],
"package": "warren2009-calciumwavepropagation",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "This a model from the article: Mathematical modelling of calcium wave propagation in mammalian airwayepithelium: evidence for regenerative ATP release. It can be used to explore systemsbiology warren2009 calciumwavepropagation model1006230018 dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagewarren2009-calciumwavepropagation
Created2026-05-17
Updated2026-06-13
generegulationmetabolismphysiologysystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother