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IL-6 has been proposed to favor the development of Th2 responses and play an important role in the communication between cells of multicellular organisms. They are involved in the regulation of comple.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_interferon_gamma_interferon_gamma_receptor",
"label": "Initial Interferon Gamma Interferon Gamma Receptor",
"units": "native source value",
"default": 800,
"maps_to": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model.initial_interferon_gamma_interferon_gamma_receptor",
"description": "Initial Interferon Gamma Interferon Gamma Receptor. Sets the initial value of bundled SBML species `mwd7270399_0429_4c85_920a_de2e0ae74440`."
}
],
"outputs": [
{
"name": "interferon_g",
"maps_to": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model.interferon_g"
},
{
"name": "interferon_gr",
"maps_to": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model.interferon_gr"
},
{
"name": "interferon_gamma_interferon_gamma_receptor",
"maps_to": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model.interferon_gamma_interferon_gamma_receptor"
},
{
"name": "unresolved_infection_observable_1",
"maps_to": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model.unresolved_infection_observable_1"
},
{
"name": "toll_like_receptor_6_complex",
"maps_to": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model.toll_like_receptor_6_complex"
},
{
"name": "state",
"maps_to": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model.state"
},
{
"name": "summary",
"maps_to": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model.summary"
},
{
"name": "species_labels",
"maps_to": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model.species_labels"
}
]
},
"title": "Soni2018 - IL6 induced M2 Phenotype in Leishmania major infected macrophage Lab",
"models": [
{
"path": "models/core",
"alias": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model_state"
],
"from": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model.state"
},
{
"to": [
"visualisation.immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model_summary"
],
"from": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model.summary"
},
{
"to": [
"visualisation.immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model_species_labels"
],
"from": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model.species_labels"
}
],
"package": "soni2018-il6-induced-m2-phenotype-in-leishmania-major",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "IL-6 has been proposed to favor the development of Th2 responses and play an important role in the communication between cells of multicellular organisms. They are involved in the regulation of comple.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagesoni2018-il6-induced-m2-phenotype-in-leishmania-major
Created2026-05-15
Updated2026-06-13
immunologysbmlbiomodels_ebifaithfulcuratedvisualisationother