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Source-faithful physiology lab for Nazaret, Heiske, Thurley and Mazat, 2009. Public controls and outputs are mapped to real source symbols for source-model physiology.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_membrane_potential",
"label": "Initial Membrane Potential",
"maps_to": "physiology_cellml_nazaret_heiske_thurley_and_mazat_2009_nazaretheiskethurleymazat2009_model.initial_membrane_potential",
"description": "Initial value for Membrane Potential. Maps to source symbol `delta_psi`. Units: millivolt. Naming evidence: source metadata names `delta_psi` as `membrane potential`.",
"accepted_units": [
"millivolt"
]
},
{
"name": "initial_adenosine_triphospahte",
"label": "Initial Adenosine Triphospahte",
"maps_to": "physiology_cellml_nazaret_heiske_thurley_and_mazat_2009_nazaretheiskethurleymazat2009_model.initial_adenosine_triphospahte",
"description": "Initial value for Adenosine Triphospahte. Maps to source symbol `ATP`. Units: micromolar. Naming evidence: source metadata names `ATP` as `adenosine triphospahte`.",
"accepted_units": [
"micromolar"
]
}
],
"outputs": [
{
"name": "state",
"label": "Selected Source State",
"maps_to": "physiology_cellml_nazaret_heiske_thurley_and_mazat_2009_nazaretheiskethurleymazat2009_model.state"
},
{
"name": "summary",
"label": "Simulation Summary",
"maps_to": "physiology_cellml_nazaret_heiske_thurley_and_mazat_2009_nazaretheiskethurleymazat2009_model.summary"
},
{
"name": "trajectory",
"label": "Source Trajectory",
"maps_to": "physiology_cellml_nazaret_heiske_thurley_and_mazat_2009_nazaretheiskethurleymazat2009_model.trajectory"
},
{
"name": "variable_labels",
"label": "Observable Labels",
"maps_to": "physiology_cellml_nazaret_heiske_thurley_and_mazat_2009_nazaretheiskethurleymazat2009_model.variable_labels"
},
{
"name": "adenosine_triphospahte",
"label": "Adenosine Triphospahte",
"maps_to": "physiology_cellml_nazaret_heiske_thurley_and_mazat_2009_nazaretheiskethurleymazat2009_model.adenosine_triphospahte",
"description": "Adenosine Triphospahte. Maps to source symbol `ATP`. Units: micromolar. Naming evidence: source metadata names `ATP` as `adenosine triphospahte`."
},
{
"name": "atp_crit_delta_psi",
"label": "ATP Crit Delta Psi",
"maps_to": "physiology_cellml_nazaret_heiske_thurley_and_mazat_2009_nazaretheiskethurleymazat2009_model.atp_crit_delta_psi",
"description": "ATP Crit Delta Psi. Maps to source symbol `ATP_crit_delta_psi`. Units: micromolar. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "atp_crit_delta_psi_f",
"label": "ATP Crit Delta Psi F",
"maps_to": "physiology_cellml_nazaret_heiske_thurley_and_mazat_2009_nazaretheiskethurleymazat2009_model.atp_crit_delta_psi_f",
"description": "ATP Crit Delta Psi F. Maps to source symbol `F`. Units: coulomb_per_mole. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "atp_crit_delta_psi_pi",
"label": "ATP Crit Delta Psi Pi",
"maps_to": "physiology_cellml_nazaret_heiske_thurley_and_mazat_2009_nazaretheiskethurleymazat2009_model.atp_crit_delta_psi_pi",
"description": "ATP Crit Delta Psi Pi. Maps to source symbol `Pi`. Units: millimolar. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "atp_crit_delta_psi_r",
"label": "ATP Crit Delta Psi R",
"maps_to": "physiology_cellml_nazaret_heiske_thurley_and_mazat_2009_nazaretheiskethurleymazat2009_model.atp_crit_delta_psi_r",
"description": "ATP Crit Delta Psi R. Maps to source symbol `R`. Units: joule_per_mole_kelvin. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "atp_crit_delta_psi_t",
"label": "ATP Crit Delta Psi T",
"maps_to": "physiology_cellml_nazaret_heiske_thurley_and_mazat_2009_nazaretheiskethurleymazat2009_model.atp_crit_delta_psi_t",
"description": "ATP Crit Delta Psi T. Maps to source symbol `T`. Units: kelvin. Naming evidence: source symbol, component, or units provide a direct public name."
}
]
},
"title": "Nazaret2009 - Mitochondrial Energetic Metabolism Simplified Tca Cycle Lab",
"models": [
{
"path": "models/core",
"alias": "physiology_cellml_nazaret_heiske_thurley_and_mazat_2009_nazaretheiskethurleymazat2009_model",
"parameters": {
"model_path": "data/nazaret_2009.cellml",
"integration_step": 0.01
}
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.physiology_cellml_nazaret_heiske_thurley_and_mazat_2009_nazaretheiskethurleymazat2009_model_state"
],
"from": "physiology_cellml_nazaret_heiske_thurley_and_mazat_2009_nazaretheiskethurleymazat2009_model.state"
},
{
"to": [
"visualisation.physiology_cellml_nazaret_heiske_thurley_and_mazat_2009_nazaretheiskethurleymazat2009_model_summary"
],
"from": "physiology_cellml_nazaret_heiske_thurley_and_mazat_2009_nazaretheiskethurleymazat2009_model.summary"
},
{
"to": [
"visualisation.physiology_cellml_nazaret_heiske_thurley_and_mazat_2009_nazaretheiskethurleymazat2009_model_trajectory"
],
"from": "physiology_cellml_nazaret_heiske_thurley_and_mazat_2009_nazaretheiskethurleymazat2009_model.trajectory"
},
{
"to": [
"visualisation.physiology_cellml_nazaret_heiske_thurley_and_mazat_2009_nazaretheiskethurleymazat2009_model_variable_labels"
],
"from": "physiology_cellml_nazaret_heiske_thurley_and_mazat_2009_nazaretheiskethurleymazat2009_model.variable_labels"
}
],
"package": "nazaret2009-mitochondrial-energetic-metabolism-simplifi-a8f05280",
"runtime": {
"duration": 0.01,
"settle_steps": 1,
"initial_inputs": {},
"communication_step": 0.01
},
"version": "1.0.0",
"description": "Source-faithful physiology lab for Nazaret, Heiske, Thurley and Mazat, 2009. Public controls and outputs are mapped to real source symbols for source-model physiology.",
"schema_version": "2.0"
}Runtime
Duration0.01
Comms Step0.01
Settle Steps1
Runs
Total0
Completed0
Failed0
Metadata
Packagenazaret2009-mitochondrial-energetic-metabolism-simplifi-a8f05280
Created2026-05-23
Updated2026-06-13
physiologycellmlphysiomefaithfulvisualisationother