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This model reproduces figure 5 and figure 4(B)of the paper, with Kinh represented by [G-GTP]. It can be used to explore systemsbiology thomsen1989 adenylatecyclase BioModels0000000080 dynamics and compare simulation behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_g_gdp",
"label": "Initial G Gdp",
"maps_to": "systemsbiology_sbml_thomsen1989_adenylatecyclase_biomd0000000080_model.initial_g_gdp",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `G_GDP`."
},
{
"name": "initial_g_gtp",
"label": "Initial G Gtp",
"maps_to": "systemsbiology_sbml_thomsen1989_adenylatecyclase_biomd0000000080_model.initial_g_gtp",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `G_GTP`."
},
{
"name": "initial_drg_gtp",
"label": "Initial Drg Gtp",
"maps_to": "systemsbiology_sbml_thomsen1989_adenylatecyclase_biomd0000000080_model.initial_drg_gtp",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `DRG_GTP`."
},
{
"name": "initial_drg_gdp",
"label": "Initial Drg Gdp",
"maps_to": "systemsbiology_sbml_thomsen1989_adenylatecyclase_biomd0000000080_model.initial_drg_gdp",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `DRG_GDP`."
},
{
"name": "initial_model_state_gtp",
"label": "Initial Model State Gtp",
"maps_to": "systemsbiology_sbml_thomsen1989_adenylatecyclase_biomd0000000080_model.initial_model_state_gtp",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `GTP`."
},
{
"name": "initial_model_state_gdp",
"label": "Initial Model State Gdp",
"maps_to": "systemsbiology_sbml_thomsen1989_adenylatecyclase_biomd0000000080_model.initial_model_state_gdp",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `GDP`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_thomsen1989_adenylatecyclase_biomd0000000080_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_thomsen1989_adenylatecyclase_biomd0000000080_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_thomsen1989_adenylatecyclase_biomd0000000080_model.species_labels"
},
{
"name": "g_gdp",
"maps_to": "systemsbiology_sbml_thomsen1989_adenylatecyclase_biomd0000000080_model.g_gdp"
},
{
"name": "g_gtp",
"maps_to": "systemsbiology_sbml_thomsen1989_adenylatecyclase_biomd0000000080_model.g_gtp"
},
{
"name": "drg_gtp",
"maps_to": "systemsbiology_sbml_thomsen1989_adenylatecyclase_biomd0000000080_model.drg_gtp"
},
{
"name": "drg_gdp",
"maps_to": "systemsbiology_sbml_thomsen1989_adenylatecyclase_biomd0000000080_model.drg_gdp"
},
{
"name": "gtp",
"maps_to": "systemsbiology_sbml_thomsen1989_adenylatecyclase_biomd0000000080_model.gtp"
},
{
"name": "gdp",
"maps_to": "systemsbiology_sbml_thomsen1989_adenylatecyclase_biomd0000000080_model.gdp"
}
]
},
"tags": [
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Thomsen1989 Adenylatecyclase Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_thomsen1989_adenylatecyclase_biomd0000000080_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_thomsen1989_adenylatecyclase_biomd0000000080_model_state"
],
"from": "systemsbiology_sbml_thomsen1989_adenylatecyclase_biomd0000000080_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_thomsen1989_adenylatecyclase_biomd0000000080_model_summary"
],
"from": "systemsbiology_sbml_thomsen1989_adenylatecyclase_biomd0000000080_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_thomsen1989_adenylatecyclase_biomd0000000080_model_species_labels"
],
"from": "systemsbiology_sbml_thomsen1989_adenylatecyclase_biomd0000000080_model.species_labels"
}
],
"package": "thomsen1989-adenylatecyclase",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "This model reproduces figure 5 and figure 4(B)of the paper, with Kinh represented by [G-GTP]. It can be used to explore systemsbiology thomsen1989 adenylatecyclase BioModels0000000080 dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagethomsen1989-adenylatecyclase
Created2026-05-17
Updated2026-06-13
systemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother