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This a model from the article: Modelling the onset of Type 1 diabetes: can impaired macrophage phagocytosis make the difference between health and disease? It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.
Manifest
{
"io": {
"inputs": [],
"outputs": [
{
"name": "unresolved_immune_observable_1",
"maps_to": "immunology_sbml_maree2006_duca_type1diabetesmodel_biomd0000000381_model.unresolved_immune_observable_1"
},
{
"name": "unresolved_immune_observable_2",
"maps_to": "immunology_sbml_maree2006_duca_type1diabetesmodel_biomd0000000381_model.unresolved_immune_observable_2"
},
{
"name": "unresolved_immune_observable_3",
"maps_to": "immunology_sbml_maree2006_duca_type1diabetesmodel_biomd0000000381_model.unresolved_immune_observable_3"
},
{
"name": "unresolved_immune_observable_4",
"maps_to": "immunology_sbml_maree2006_duca_type1diabetesmodel_biomd0000000381_model.unresolved_immune_observable_4"
},
{
"name": "unresolved_immune_observable_5",
"maps_to": "immunology_sbml_maree2006_duca_type1diabetesmodel_biomd0000000381_model.unresolved_immune_observable_5"
},
{
"name": "state",
"maps_to": "immunology_sbml_maree2006_duca_type1diabetesmodel_biomd0000000381_model.state"
},
{
"name": "summary",
"maps_to": "immunology_sbml_maree2006_duca_type1diabetesmodel_biomd0000000381_model.summary"
},
{
"name": "species_labels",
"maps_to": "immunology_sbml_maree2006_duca_type1diabetesmodel_biomd0000000381_model.species_labels"
}
]
},
"title": "Maree2006 DuCa Type1DiabetesModel Lab",
"models": [
{
"path": "models/core",
"alias": "immunology_sbml_maree2006_duca_type1diabetesmodel_biomd0000000381_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.immunology_sbml_maree2006_duca_type1diabetesmodel_biomd0000000381_model_state"
],
"from": "immunology_sbml_maree2006_duca_type1diabetesmodel_biomd0000000381_model.state"
},
{
"to": [
"visualisation.immunology_sbml_maree2006_duca_type1diabetesmodel_biomd0000000381_model_summary"
],
"from": "immunology_sbml_maree2006_duca_type1diabetesmodel_biomd0000000381_model.summary"
},
{
"to": [
"visualisation.immunology_sbml_maree2006_duca_type1diabetesmodel_biomd0000000381_model_species_labels"
],
"from": "immunology_sbml_maree2006_duca_type1diabetesmodel_biomd0000000381_model.species_labels"
}
],
"caveats": "No scientifically safe input was exposed in this pass: the bundled SBML did not provide a headline species initial value or meaningfully named constant/intervention parameter that could be surfaced without turning raw source symbols into unsupported biological claims.",
"package": "maree2006-duca-type1diabetesmodel",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "This a model from the article: Modelling the onset of Type 1 diabetes: can impaired macrophage phagocytosis make the difference between health and disease? It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagemaree2006-duca-type1diabetesmodel
Created2026-05-15
Updated2026-06-13
immunologysbmlbiomodels_ebifaithfulcuratedvisualisationother