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Source-faithful physiology lab for Novak, Tyson, 1997. Public controls and outputs are mapped to real source symbols for source-model physiology.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_intermediary_enzyme",
"label": "Initial Intermediary Enzyme",
"maps_to": "physiology_cellml_novak_tyson_1997_novaktyson1997_model.initial_intermediary_enzyme",
"description": "Initial value for Intermediary Enzyme. Maps to source symbol `IE`. Units: dimensionless. Naming evidence: source metadata names `IE` as `intermediary enzyme`.",
"accepted_units": [
"dimensionless"
]
},
{
"name": "initial_cdc13_cdc2_complex",
"label": "Initial Cdc13 Cdc2 Complex",
"maps_to": "physiology_cellml_novak_tyson_1997_novaktyson1997_model.initial_cdc13_cdc2_complex",
"description": "Initial value for Cdc13 Cdc2 Complex. Maps to source symbol `G2K`. Units: dimensionless. Naming evidence: source metadata names `G2K` as `Cdc13-Cdc2 complex`.",
"accepted_units": [
"dimensionless"
]
}
],
"outputs": [
{
"name": "state",
"label": "Selected Source State",
"maps_to": "physiology_cellml_novak_tyson_1997_novaktyson1997_model.state"
},
{
"name": "summary",
"label": "Simulation Summary",
"maps_to": "physiology_cellml_novak_tyson_1997_novaktyson1997_model.summary"
},
{
"name": "trajectory",
"label": "Source Trajectory",
"maps_to": "physiology_cellml_novak_tyson_1997_novaktyson1997_model.trajectory"
},
{
"name": "variable_labels",
"label": "Observable Labels",
"maps_to": "physiology_cellml_novak_tyson_1997_novaktyson1997_model.variable_labels"
},
{
"name": "intracellular_potassium",
"label": "Intracellular Potassium",
"maps_to": "physiology_cellml_novak_tyson_1997_novaktyson1997_model.intracellular_potassium",
"description": "Intracellular Potassium. Maps to source symbol `ki`. Units: first_order_rate_constant. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "intermediary_enzyme",
"label": "Intermediary Enzyme",
"maps_to": "physiology_cellml_novak_tyson_1997_novaktyson1997_model.intermediary_enzyme",
"description": "Intermediary Enzyme. Maps to source symbol `IE`. Units: dimensionless. Naming evidence: source metadata names `IE` as `intermediary enzyme`."
},
{
"name": "cdc25",
"label": "Cdc25",
"maps_to": "physiology_cellml_novak_tyson_1997_novaktyson1997_model.cdc25",
"description": "Cdc25. Maps to source symbol `Cdc25`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "cig2_cdc2_complex",
"label": "Cig2 Cdc2 Complex",
"maps_to": "physiology_cellml_novak_tyson_1997_novaktyson1997_model.cig2_cdc2_complex",
"description": "Cig2 Cdc2 Complex. Maps to source symbol `G1K`. Units: dimensionless. Naming evidence: source metadata names `G1K` as `Cig2-Cdc2 complex`."
},
{
"name": "cig2_cdc2_rum1_complex",
"label": "Cig2 Cdc2 Rum1 Complex",
"maps_to": "physiology_cellml_novak_tyson_1997_novaktyson1997_model.cig2_cdc2_rum1_complex",
"description": "Cig2 Cdc2 Rum1 Complex. Maps to source symbol `G1R`. Units: dimensionless. Naming evidence: source metadata names `G1R` as `Cig2-Cdc2-Rum1 complex`."
},
{
"name": "rum1",
"label": "Rum1",
"maps_to": "physiology_cellml_novak_tyson_1997_novaktyson1997_model.rum1",
"description": "Rum1. Maps to source symbol `R`. Units: dimensionless. Naming evidence: source metadata names `R` as `Rum1`."
}
]
},
"title": "Novak1997 - Tyson Control DNA Replication Fission Yeast Lab",
"models": [
{
"path": "models/core",
"alias": "physiology_cellml_novak_tyson_1997_novaktyson1997_model",
"parameters": {
"model_path": "data/novak_tyson_1997.cellml",
"integration_step": 0.01
}
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.physiology_cellml_novak_tyson_1997_novaktyson1997_model_state"
],
"from": "physiology_cellml_novak_tyson_1997_novaktyson1997_model.state"
},
{
"to": [
"visualisation.physiology_cellml_novak_tyson_1997_novaktyson1997_model_summary"
],
"from": "physiology_cellml_novak_tyson_1997_novaktyson1997_model.summary"
},
{
"to": [
"visualisation.physiology_cellml_novak_tyson_1997_novaktyson1997_model_trajectory"
],
"from": "physiology_cellml_novak_tyson_1997_novaktyson1997_model.trajectory"
},
{
"to": [
"visualisation.physiology_cellml_novak_tyson_1997_novaktyson1997_model_variable_labels"
],
"from": "physiology_cellml_novak_tyson_1997_novaktyson1997_model.variable_labels"
}
],
"package": "novak1997-tyson-control-dna-replication-fission-yeast",
"runtime": {
"duration": 0.01,
"settle_steps": 1,
"initial_inputs": {},
"communication_step": 0.01
},
"version": "1.0.0",
"description": "Source-faithful physiology lab for Novak, Tyson, 1997. Public controls and outputs are mapped to real source symbols for source-model physiology.",
"schema_version": "2.0"
}Runtime
Duration0.01
Comms Step0.01
Settle Steps1
Runs
Total0
Completed0
Failed0
Metadata
Packagenovak1997-tyson-control-dna-replication-fission-yeast
Created2026-05-23
Updated2026-06-13
physiologycellmlphysiomefaithfulvisualisationother