Padala2017- ERK, PI3K/Akt and Wnt signalling network (PTEN mutation) Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_p_egfr",
        "label": "Initial P EGFR",
        "maps_to": "signaling_sbml_padala2017_erk_pi3k_akt_and_wnt_signalling_netwo_biomd0000000655_model.initial_p_egfr",
        "description": "Initial level of P EGFR. Maps to SBML symbol `pEGFR`; exposed as a traceable initial-condition perturbation."
      },
      {
        "name": "initial_bound_egfr",
        "label": "Initial bound EGFR",
        "maps_to": "signaling_sbml_padala2017_erk_pi3k_akt_and_wnt_signalling_netwo_biomd0000000655_model.initial_bound_egfr",
        "description": "Initial level of bound EGFR. Maps to SBML symbol `bEGFR`; exposed as a traceable initial-condition perturbation."
      },
      {
        "name": "initial_egf",
        "label": "Initial EGF",
        "maps_to": "signaling_sbml_padala2017_erk_pi3k_akt_and_wnt_signalling_netwo_biomd0000000655_model.initial_egf",
        "description": "Initial level of EGF. Maps to SBML symbol `EGF`; exposed as a traceable initial-condition perturbation."
      }
    ],
    "outputs": [
      {
        "name": "apc_axin",
        "label": "APC Axin",
        "maps_to": "signaling_sbml_padala2017_erk_pi3k_akt_and_wnt_signalling_netwo_biomd0000000655_model.apc_axin",
        "description": "APC Axin. Maps to SBML symbol `APCAxin` and is emitted in native SBML units."
      },
      {
        "name": "apc_axin_gsk3b",
        "label": "APC Axin Gsk3b",
        "maps_to": "signaling_sbml_padala2017_erk_pi3k_akt_and_wnt_signalling_netwo_biomd0000000655_model.apc_axin_gsk3b",
        "description": "APC Axin Gsk3b. Maps to SBML symbol `APCAxinGSK3B` and is emitted in native SBML units."
      },
      {
        "name": "apc_b_catenin",
        "label": "APC B Catenin",
        "maps_to": "signaling_sbml_padala2017_erk_pi3k_akt_and_wnt_signalling_netwo_biomd0000000655_model.apc_b_catenin",
        "description": "APC B Catenin. Maps to SBML symbol `APCBCatenin` and is emitted in native SBML units."
      },
      {
        "name": "state",
        "label": "Observable state",
        "maps_to": "signaling_sbml_padala2017_erk_pi3k_akt_and_wnt_signalling_netwo_biomd0000000655_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation summary",
        "maps_to": "signaling_sbml_padala2017_erk_pi3k_akt_and_wnt_signalling_netwo_biomd0000000655_model.summary"
      },
      {
        "name": "species_labels",
        "label": "Observable labels",
        "maps_to": "signaling_sbml_padala2017_erk_pi3k_akt_and_wnt_signalling_netwo_biomd0000000655_model.species_labels"
      }
    ]
  },
  "tags": [
    "signaling",
    "systems",
    "systems-biology",
    "sbml",
    "faithful",
    "biomodels_ebi",
    "mapk",
    "ras-erk",
    "pi3k-akt",
    "wnt",
    "oncology"
  ],
  "title": "Padala2017- ERK, PI3K/Akt and Wnt signalling network (PTEN mutation) Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "signaling_sbml_padala2017_erk_pi3k_akt_and_wnt_signalling_netwo_biomd0000000655_model"
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.signaling_sbml_padala2017_erk_pi3k_akt_and_wnt_signalling_netwo_biomd0000000655_model_state"
      ],
      "from": "signaling_sbml_padala2017_erk_pi3k_akt_and_wnt_signalling_netwo_biomd0000000655_model.state"
    },
    {
      "to": [
        "visualisation.signaling_sbml_padala2017_erk_pi3k_akt_and_wnt_signalling_netwo_biomd0000000655_model_summary"
      ],
      "from": "signaling_sbml_padala2017_erk_pi3k_akt_and_wnt_signalling_netwo_biomd0000000655_model.summary"
    },
    {
      "to": [
        "visualisation.signaling_sbml_padala2017_erk_pi3k_akt_and_wnt_signalling_netwo_biomd0000000655_model_species_labels"
      ],
      "from": "signaling_sbml_padala2017_erk_pi3k_akt_and_wnt_signalling_netwo_biomd0000000655_model.species_labels"
    }
  ],
  "package": "padala2017-erk-pi3k-akt-and-wnt-signalling-netwo-biomd0000000655",
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "version": "1.0.0",
  "description": "Clean Biosimulant lab for MAPK/ERK receptor signaling. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.",
  "schema_version": "2.0"
}