About lab
One published Lab
Build with this Lab. Run it anywhere.
Use the same immutable release locally or through managed cloud execution, with its exact version and provenance preserved.
Preparing exact examples…
This model is from the article: On the encoding and decoding of calcium signals in hepatocytes Ann Zahle Larsen, Lars Folke Olsen and Ursula Kummera Biophysical Chemistry Volume 107, Issue 1, 1 Januar. It can be used to explore systemsbiology larsen2004 calciumspiking BioModels0000000330 dynamics and compare simulation behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_calcium_er",
"label": "Initial Calcium Er",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.initial_calcium_er",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Ca_ER`."
},
{
"name": "initial_g_alpha",
"label": "Initial G Alpha",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.initial_g_alpha",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `G_alpha`."
},
{
"name": "initial_calcium_cyt",
"label": "Initial Calcium Cyt",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.initial_calcium_cyt",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Ca_cyt`."
},
{
"name": "initial_calcium_mit",
"label": "Initial Calcium Mit",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.initial_calcium_mit",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Ca_mit`."
},
{
"name": "initial_model_state_plc",
"label": "Initial Model State Plc",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.initial_model_state_plc",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `PLC`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.species_labels"
},
{
"name": "calcium_er",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.calcium_er"
},
{
"name": "g_alpha",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.g_alpha"
},
{
"name": "calcium_cyt",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.calcium_cyt"
},
{
"name": "calcium_mit",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.calcium_mit"
},
{
"name": "plc",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.plc"
}
]
},
"tags": [
"physiology",
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Larsen2004 Calciumspiking Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model_state"
],
"from": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model_summary"
],
"from": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model_species_labels"
],
"from": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.species_labels"
}
],
"package": "larsen2004-calciumspiking",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "This model is from the article: On the encoding and decoding of calcium signals in hepatocytes Ann Zahle Larsen, Lars Folke Olsen and Ursula Kummera Biophysical Chemistry Volume 107, Issue 1, 1 Januar. It can be used to explore systemsbiology larsen2004 calciumspiking BioModels0000000330 dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagelarsen2004-calciumspiking
Created2026-05-17
Updated2026-06-13
physiologysystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother