Simon2025 - Neuroblastoma energy metabolism Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_glucose",
        "units": "native SBML value",
        "default": 2.72988078351158,
        "maps_to": "metabolism_sbml_simon2025_neuroblastoma_energy_metabolism_model2502190001_model.initial_glucose",
        "description": "Initial condition for glucose. Maps to bundled SBML symbol `glc`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_adp",
        "units": "native SBML value",
        "default": 4.79944686874058,
        "maps_to": "metabolism_sbml_simon2025_neuroblastoma_energy_metabolism_model2502190001_model.initial_adp",
        "description": "Initial condition for adp. Maps to bundled SBML symbol `adp`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_atp",
        "units": "native SBML value",
        "default": 8.14466765495666,
        "maps_to": "metabolism_sbml_simon2025_neuroblastoma_energy_metabolism_model2502190001_model.initial_atp",
        "description": "Initial condition for atp. Maps to bundled SBML symbol `atp`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_metabolic_pathway_state_4",
        "units": "native SBML value",
        "default": 0.601679350245062,
        "maps_to": "metabolism_sbml_simon2025_neuroblastoma_energy_metabolism_model2502190001_model.initial_metabolic_pathway_state_4",
        "description": "Initial condition for metabolic pathway state 4. Maps to bundled SBML symbol `glc6p`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_fructose_6_phosphate",
        "units": "native SBML value",
        "default": 0.0499563769212773,
        "maps_to": "metabolism_sbml_simon2025_neuroblastoma_energy_metabolism_model2502190001_model.initial_fructose_6_phosphate",
        "description": "Initial condition for fructose 6 phosphate. Maps to bundled SBML symbol `fru6p`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      }
    ],
    "outputs": [
      {
        "name": "glucose",
        "maps_to": "metabolism_sbml_simon2025_neuroblastoma_energy_metabolism_model2502190001_model.glucose"
      },
      {
        "name": "adp",
        "maps_to": "metabolism_sbml_simon2025_neuroblastoma_energy_metabolism_model2502190001_model.adp"
      },
      {
        "name": "atp",
        "maps_to": "metabolism_sbml_simon2025_neuroblastoma_energy_metabolism_model2502190001_model.atp"
      },
      {
        "name": "metabolic_pathway_state_4",
        "maps_to": "metabolism_sbml_simon2025_neuroblastoma_energy_metabolism_model2502190001_model.metabolic_pathway_state_4"
      },
      {
        "name": "fructose_6_phosphate",
        "maps_to": "metabolism_sbml_simon2025_neuroblastoma_energy_metabolism_model2502190001_model.fructose_6_phosphate"
      },
      {
        "name": "observable_values",
        "maps_to": "metabolism_sbml_simon2025_neuroblastoma_energy_metabolism_model2502190001_model.observable_values"
      },
      {
        "name": "run_summary",
        "maps_to": "metabolism_sbml_simon2025_neuroblastoma_energy_metabolism_model2502190001_model.run_summary"
      },
      {
        "name": "observable_labels",
        "maps_to": "metabolism_sbml_simon2025_neuroblastoma_energy_metabolism_model2502190001_model.observable_labels"
      }
    ]
  },
  "title": "Simon2025 - Neuroblastoma energy metabolism Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "metabolism_sbml_simon2025_neuroblastoma_energy_metabolism_model2502190001_model",
      "parameters": {
        "model_path": "data/MODEL2502190001.xml",
        "integration_step": 0.1
      }
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.metabolism_sbml_simon2025_neuroblastoma_energy_metabolism_model2502190001_model_observable_values"
      ],
      "from": "metabolism_sbml_simon2025_neuroblastoma_energy_metabolism_model2502190001_model.observable_values"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_simon2025_neuroblastoma_energy_metabolism_model2502190001_model_run_summary"
      ],
      "from": "metabolism_sbml_simon2025_neuroblastoma_energy_metabolism_model2502190001_model.run_summary"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_simon2025_neuroblastoma_energy_metabolism_model2502190001_model_observable_labels"
      ],
      "from": "metabolism_sbml_simon2025_neuroblastoma_energy_metabolism_model2502190001_model.observable_labels"
    }
  ],
  "package": "simon2025-neuroblastoma-energy-metabolism",
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "version": "1.0.0",
  "description": "Metabolism Simon2025Neuroblastoma Energy Metabolism Model2502190001Model models core biological dynamics as a OTHER simulation curated from biomodels_ebi (biomodels_ebi:MODEL2502190001), focused on metabolism. When you run it, you can track state over time and compare response patterns across parameter settings.",
  "schema_version": "2.0"
}