About lab
One published Lab
Build with this Lab. Run it anywhere.
Use the same immutable release locally or through managed cloud execution, with its exact version and provenance preserved.
Preparing exact examples…
The paper describes a spatio-temporal mathematical model, in the form of a moving boundary problem, to explain cancer dormancy is developed. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_immune_cell_x",
"label": "Initial Immune Cell X",
"units": "native source value",
"default": 0.3,
"maps_to": "immunology_sbml_malinzi2018_tumour_immune_interaction_model_biomd0000000809_model.initial_immune_cell_x",
"description": "Initial Immune Cell X. Sets the initial value of bundled SBML species `x`."
},
{
"name": "initial_tumour_cell_y",
"label": "Initial Tumour Cell Y",
"units": "native source value",
"default": 0.8,
"maps_to": "immunology_sbml_malinzi2018_tumour_immune_interaction_model_biomd0000000809_model.initial_tumour_cell_y",
"description": "Initial Tumour Cell Y. Sets the initial value of bundled SBML species `y`."
},
{
"name": "initial_dead_tumour_cell_ystar",
"label": "Initial Dead Tumour Cell Ystar",
"units": "native source value",
"default": 0.1,
"maps_to": "immunology_sbml_malinzi2018_tumour_immune_interaction_model_biomd0000000809_model.initial_dead_tumour_cell_ystar",
"description": "Initial Dead Tumour Cell Ystar. Sets the initial value of bundled SBML species `ystar`."
},
{
"name": "initial_chemokine_concentration_u",
"label": "Initial Chemokine Concentration U",
"units": "native source value",
"default": 0.000001,
"maps_to": "immunology_sbml_malinzi2018_tumour_immune_interaction_model_biomd0000000809_model.initial_chemokine_concentration_u",
"description": "Initial Chemokine Concentration U. Sets the initial value of bundled SBML species `u`."
},
{
"name": "immune_cell_x_proliferation_rate",
"label": "Immune Cell X Proliferation Rate",
"units": "native source value",
"default": 3.0218,
"maps_to": "immunology_sbml_malinzi2018_tumour_immune_interaction_model_biomd0000000809_model.immune_cell_x_proliferation_rate",
"description": "Immune Cell X Proliferation Rate. Sets bundled SBML parameter `delta`."
},
{
"name": "immune_cell_x_proliferation_rate_2",
"label": "Immune Cell X Proliferation Rate 2",
"units": "native source value",
"default": 2.02,
"maps_to": "immunology_sbml_malinzi2018_tumour_immune_interaction_model_biomd0000000809_model.immune_cell_x_proliferation_rate_2",
"description": "Immune Cell X Proliferation Rate 2. Sets bundled SBML parameter `gamma`."
}
],
"outputs": [
{
"name": "immune_cell_x",
"maps_to": "immunology_sbml_malinzi2018_tumour_immune_interaction_model_biomd0000000809_model.immune_cell_x"
},
{
"name": "tumour_cell_y",
"maps_to": "immunology_sbml_malinzi2018_tumour_immune_interaction_model_biomd0000000809_model.tumour_cell_y"
},
{
"name": "dead_tumour_cell_ystar",
"maps_to": "immunology_sbml_malinzi2018_tumour_immune_interaction_model_biomd0000000809_model.dead_tumour_cell_ystar"
},
{
"name": "chemokine_concentration_u",
"maps_to": "immunology_sbml_malinzi2018_tumour_immune_interaction_model_biomd0000000809_model.chemokine_concentration_u"
},
{
"name": "state",
"maps_to": "immunology_sbml_malinzi2018_tumour_immune_interaction_model_biomd0000000809_model.state"
},
{
"name": "summary",
"maps_to": "immunology_sbml_malinzi2018_tumour_immune_interaction_model_biomd0000000809_model.summary"
},
{
"name": "species_labels",
"maps_to": "immunology_sbml_malinzi2018_tumour_immune_interaction_model_biomd0000000809_model.species_labels"
}
]
},
"title": "Malinzi2018 - tumour-immune interaction model Lab",
"models": [
{
"path": "models/core",
"alias": "immunology_sbml_malinzi2018_tumour_immune_interaction_model_biomd0000000809_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.immunology_sbml_malinzi2018_tumour_immune_interaction_model_biomd0000000809_model_state"
],
"from": "immunology_sbml_malinzi2018_tumour_immune_interaction_model_biomd0000000809_model.state"
},
{
"to": [
"visualisation.immunology_sbml_malinzi2018_tumour_immune_interaction_model_biomd0000000809_model_summary"
],
"from": "immunology_sbml_malinzi2018_tumour_immune_interaction_model_biomd0000000809_model.summary"
},
{
"to": [
"visualisation.immunology_sbml_malinzi2018_tumour_immune_interaction_model_biomd0000000809_model_species_labels"
],
"from": "immunology_sbml_malinzi2018_tumour_immune_interaction_model_biomd0000000809_model.species_labels"
}
],
"package": "malinzi2018-tumour-immune-interaction-model",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "The paper describes a spatio-temporal mathematical model, in the form of a moving boundary problem, to explain cancer dormancy is developed. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagemalinzi2018-tumour-immune-interaction-model
Created2026-05-15
Updated2026-06-13
immunologysbmlbiomodels_ebifaithfulcuratedvisualisationother