Dubey2008 - Modeling the interaction between avascular cancerous cells and acquired immune response Lab

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MODELING THE INTERACTION BETWEEN AVASCULAR CANCEROUS CELLS AND ACQUIRED IMMUNE RESPONSEB. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.
Manifest
{
  "io": {
    "inputs": [
      {
        "name": "initial_unresolved_tumor_observable_1",
        "label": "Initial Unresolved Tumor Observable 1",
        "units": "native source value",
        "default": 9,
        "maps_to": "immunology_sbml_dubey2008_modeling_the_interaction_between_avasc_biomd0000000886_model.initial_unresolved_tumor_observable_1",
        "description": "Initial Unresolved Tumor Observable 1. Sets the initial value of bundled SBML species `T`."
      },
      {
        "name": "initial_unresolved_tumor_observable_2",
        "label": "Initial Unresolved Tumor Observable 2",
        "units": "native source value",
        "default": 7,
        "maps_to": "immunology_sbml_dubey2008_modeling_the_interaction_between_avasc_biomd0000000886_model.initial_unresolved_tumor_observable_2",
        "description": "Initial Unresolved Tumor Observable 2. Sets the initial value of bundled SBML species `Th`."
      },
      {
        "name": "initial_unresolved_tumor_observable_3",
        "label": "Initial Unresolved Tumor Observable 3",
        "units": "native source value",
        "default": 1,
        "maps_to": "immunology_sbml_dubey2008_modeling_the_interaction_between_avasc_biomd0000000886_model.initial_unresolved_tumor_observable_3",
        "description": "Initial Unresolved Tumor Observable 3. Sets the initial value of bundled SBML species `Tc`."
      },
      {
        "name": "initial_unresolved_tumor_observable_4",
        "label": "Initial Unresolved Tumor Observable 4",
        "units": "native source value",
        "default": 1,
        "maps_to": "immunology_sbml_dubey2008_modeling_the_interaction_between_avasc_biomd0000000886_model.initial_unresolved_tumor_observable_4",
        "description": "Initial Unresolved Tumor Observable 4. Sets the initial value of bundled SBML species `B`."
      },
      {
        "name": "initial_unresolved_tumor_observable_5",
        "label": "Initial Unresolved Tumor Observable 5",
        "units": "native source value",
        "default": 1,
        "maps_to": "immunology_sbml_dubey2008_modeling_the_interaction_between_avasc_biomd0000000886_model.initial_unresolved_tumor_observable_5",
        "description": "Initial Unresolved Tumor Observable 5. Sets the initial value of bundled SBML species `A`."
      },
      {
        "name": "introduction_of_antibody_against_cancer_rate",
        "label": "Introduction Of Antibody Against Cancer Rate",
        "units": "native source value",
        "default": 0.35,
        "maps_to": "immunology_sbml_dubey2008_modeling_the_interaction_between_avasc_biomd0000000886_model.introduction_of_antibody_against_cancer_rate",
        "description": "Introduction Of Antibody Against Cancer Rate. Sets bundled SBML parameter `mu_4`."
      },
      {
        "name": "removal_of_antibody_from_the_system_rate",
        "label": "Removal Of Antibody From The System Rate",
        "units": "native source value",
        "default": 0.3,
        "maps_to": "immunology_sbml_dubey2008_modeling_the_interaction_between_avasc_biomd0000000886_model.removal_of_antibody_from_the_system_rate",
        "description": "Removal Of Antibody From The System Rate. Sets bundled SBML parameter `mu_40`."
      },
      {
        "name": "removal_of_antibody_from_the_system_rate_2",
        "label": "Removal Of Antibody From The System Rate 2",
        "units": "native source value",
        "default": 0.5,
        "maps_to": "immunology_sbml_dubey2008_modeling_the_interaction_between_avasc_biomd0000000886_model.removal_of_antibody_from_the_system_rate_2",
        "description": "Removal Of Antibody From The System Rate 2. Sets bundled SBML parameter `delta_1`."
      }
    ],
    "outputs": [
      {
        "name": "unresolved_tumor_observable_1",
        "maps_to": "immunology_sbml_dubey2008_modeling_the_interaction_between_avasc_biomd0000000886_model.unresolved_tumor_observable_1"
      },
      {
        "name": "unresolved_tumor_observable_2",
        "maps_to": "immunology_sbml_dubey2008_modeling_the_interaction_between_avasc_biomd0000000886_model.unresolved_tumor_observable_2"
      },
      {
        "name": "unresolved_tumor_observable_3",
        "maps_to": "immunology_sbml_dubey2008_modeling_the_interaction_between_avasc_biomd0000000886_model.unresolved_tumor_observable_3"
      },
      {
        "name": "unresolved_tumor_observable_4",
        "maps_to": "immunology_sbml_dubey2008_modeling_the_interaction_between_avasc_biomd0000000886_model.unresolved_tumor_observable_4"
      },
      {
        "name": "unresolved_tumor_observable_5",
        "maps_to": "immunology_sbml_dubey2008_modeling_the_interaction_between_avasc_biomd0000000886_model.unresolved_tumor_observable_5"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_dubey2008_modeling_the_interaction_between_avasc_biomd0000000886_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_dubey2008_modeling_the_interaction_between_avasc_biomd0000000886_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_dubey2008_modeling_the_interaction_between_avasc_biomd0000000886_model.species_labels"
      }
    ]
  },
  "title": "Dubey2008 - Modeling the interaction between avascular cancerous cells and acquired immune response Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "immunology_sbml_dubey2008_modeling_the_interaction_between_avasc_biomd0000000886_model"
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_dubey2008_modeling_the_interaction_between_avasc_biomd0000000886_model_state"
      ],
      "from": "immunology_sbml_dubey2008_modeling_the_interaction_between_avasc_biomd0000000886_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_dubey2008_modeling_the_interaction_between_avasc_biomd0000000886_model_summary"
      ],
      "from": "immunology_sbml_dubey2008_modeling_the_interaction_between_avasc_biomd0000000886_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_dubey2008_modeling_the_interaction_between_avasc_biomd0000000886_model_species_labels"
      ],
      "from": "immunology_sbml_dubey2008_modeling_the_interaction_between_avasc_biomd0000000886_model.species_labels"
    }
  ],
  "package": "dubey2008-modeling-the-interaction-between-avascular-ca-72f8ee40",
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "version": "1.0.0",
  "description": "MODELING THE INTERACTION BETWEEN AVASCULAR CANCEROUS CELLS AND ACQUIRED IMMUNE RESPONSEB. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
  "schema_version": "2.0"
}
Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagedubey2008-modeling-the-interaction-between-avascular-ca-72f8ee40
Created2026-05-15
Updated2026-06-13
immunologysbmlbiomodels_ebifaithfulcuratedvisualisationother