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Mathematical model of blood coagulation investigating the effects of varied rFVIIa and TF concentration. It can be used to explore systemsbiology shibeko2012 of iia generation model1808150001 dynamics and compare simulation behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_xa_va",
"label": "Initial Xa Va",
"maps_to": "systemsbiology_sbml_shibeko2012_model_of_iia_generation_model1808150001_model.initial_xa_va",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Xa_Va`."
},
{
"name": "initial_xa_tfpi",
"label": "Initial Xa Tfpi",
"maps_to": "systemsbiology_sbml_shibeko2012_model_of_iia_generation_model1808150001_model.initial_xa_tfpi",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Xa_TFPI`."
},
{
"name": "initial_vi_ia_i_tf_xa_tfpi",
"label": "Initial Vi Ia I Tf Xa Tfpi",
"maps_to": "systemsbiology_sbml_shibeko2012_model_of_iia_generation_model1808150001_model.initial_vi_ia_i_tf_xa_tfpi",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `VIIa_i_TF_Xa_TFPI`."
},
{
"name": "initial_vi_ia_i_tf",
"label": "Initial Vi Ia I Tf",
"maps_to": "systemsbiology_sbml_shibeko2012_model_of_iia_generation_model1808150001_model.initial_vi_ia_i_tf",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `VIIa_i_TF`."
},
{
"name": "initial_vi_ia_i",
"label": "Initial Vi Ia I",
"maps_to": "systemsbiology_sbml_shibeko2012_model_of_iia_generation_model1808150001_model.initial_vi_ia_i",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `VIIa_i`."
},
{
"name": "initial_vi_ia_tf_xa_tfpi",
"label": "Initial Vi Ia Tf Xa Tfpi",
"maps_to": "systemsbiology_sbml_shibeko2012_model_of_iia_generation_model1808150001_model.initial_vi_ia_tf_xa_tfpi",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `VIIa_TF_Xa_TFPI`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_shibeko2012_model_of_iia_generation_model1808150001_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_shibeko2012_model_of_iia_generation_model1808150001_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_shibeko2012_model_of_iia_generation_model1808150001_model.species_labels"
},
{
"name": "xa_va",
"maps_to": "systemsbiology_sbml_shibeko2012_model_of_iia_generation_model1808150001_model.xa_va"
},
{
"name": "xa_tfpi",
"maps_to": "systemsbiology_sbml_shibeko2012_model_of_iia_generation_model1808150001_model.xa_tfpi"
},
{
"name": "vi_ia_i_tf_xa_tfpi",
"maps_to": "systemsbiology_sbml_shibeko2012_model_of_iia_generation_model1808150001_model.vi_ia_i_tf_xa_tfpi"
},
{
"name": "vi_ia_i_tf",
"maps_to": "systemsbiology_sbml_shibeko2012_model_of_iia_generation_model1808150001_model.vi_ia_i_tf"
},
{
"name": "vi_ia_i",
"maps_to": "systemsbiology_sbml_shibeko2012_model_of_iia_generation_model1808150001_model.vi_ia_i"
},
{
"name": "vi_ia_tf_xa_tfpi",
"maps_to": "systemsbiology_sbml_shibeko2012_model_of_iia_generation_model1808150001_model.vi_ia_tf_xa_tfpi"
}
]
},
"tags": [
"generegulation",
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Shibeko2012 Model Of Iia Generation Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_shibeko2012_model_of_iia_generation_model1808150001_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_shibeko2012_model_of_iia_generation_model1808150001_model_state"
],
"from": "systemsbiology_sbml_shibeko2012_model_of_iia_generation_model1808150001_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_shibeko2012_model_of_iia_generation_model1808150001_model_summary"
],
"from": "systemsbiology_sbml_shibeko2012_model_of_iia_generation_model1808150001_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_shibeko2012_model_of_iia_generation_model1808150001_model_species_labels"
],
"from": "systemsbiology_sbml_shibeko2012_model_of_iia_generation_model1808150001_model.species_labels"
}
],
"package": "shibeko2012-model-of-iia-generation",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "Mathematical model of blood coagulation investigating the effects of varied rFVIIa and TF concentration. It can be used to explore systemsbiology shibeko2012 of iia generation model1808150001 dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packageshibeko2012-model-of-iia-generation
Created2026-05-17
Updated2026-06-13
generegulationsystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother