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The paper describes both wild-type and mutant cells of G protein cycle by using different values of G protein deactivation. It can be used to explore systemsbiology yi2003 gproteincycle BioModels0000000072 dynamics and compare simulation behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_g_alpha_gdp",
"label": "Initial G Alpha Gdp",
"maps_to": "systemsbiology_sbml_yi2003_gproteincycle_biomd0000000072_model.initial_g_alpha_gdp",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Gd`."
},
{
"name": "initial_free_levels_of_g_beta_gamma",
"label": "Initial Free Levels Of G Beta Gamma",
"maps_to": "systemsbiology_sbml_yi2003_gproteincycle_biomd0000000072_model.initial_free_levels_of_g_beta_gamma",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Gbg`."
},
{
"name": "initial_receptor_ligand",
"label": "Initial Receptor Ligand",
"maps_to": "systemsbiology_sbml_yi2003_gproteincycle_biomd0000000072_model.initial_receptor_ligand",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `RL`."
},
{
"name": "initial_g_alpha_gtp",
"label": "Initial G Alpha Gtp",
"maps_to": "systemsbiology_sbml_yi2003_gproteincycle_biomd0000000072_model.initial_g_alpha_gtp",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Ga`."
},
{
"name": "initial_ligand",
"label": "Initial Ligand",
"maps_to": "systemsbiology_sbml_yi2003_gproteincycle_biomd0000000072_model.initial_ligand",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `L`."
},
{
"name": "initial_receptor",
"label": "Initial Receptor",
"maps_to": "systemsbiology_sbml_yi2003_gproteincycle_biomd0000000072_model.initial_receptor",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `R`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_yi2003_gproteincycle_biomd0000000072_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_yi2003_gproteincycle_biomd0000000072_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_yi2003_gproteincycle_biomd0000000072_model.species_labels"
},
{
"name": "g_alpha_gdp",
"maps_to": "systemsbiology_sbml_yi2003_gproteincycle_biomd0000000072_model.g_alpha_gdp"
},
{
"name": "free_levels_of_g_beta_gamma",
"maps_to": "systemsbiology_sbml_yi2003_gproteincycle_biomd0000000072_model.free_levels_of_g_beta_gamma"
},
{
"name": "receptor_ligand",
"maps_to": "systemsbiology_sbml_yi2003_gproteincycle_biomd0000000072_model.receptor_ligand"
},
{
"name": "g_alpha_gtp",
"maps_to": "systemsbiology_sbml_yi2003_gproteincycle_biomd0000000072_model.g_alpha_gtp"
},
{
"name": "ligand",
"maps_to": "systemsbiology_sbml_yi2003_gproteincycle_biomd0000000072_model.ligand"
},
{
"name": "receptor",
"maps_to": "systemsbiology_sbml_yi2003_gproteincycle_biomd0000000072_model.receptor"
}
]
},
"tags": [
"immunology",
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Yi2003 Gproteincycle Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_yi2003_gproteincycle_biomd0000000072_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_yi2003_gproteincycle_biomd0000000072_model_state"
],
"from": "systemsbiology_sbml_yi2003_gproteincycle_biomd0000000072_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_yi2003_gproteincycle_biomd0000000072_model_summary"
],
"from": "systemsbiology_sbml_yi2003_gproteincycle_biomd0000000072_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_yi2003_gproteincycle_biomd0000000072_model_species_labels"
],
"from": "systemsbiology_sbml_yi2003_gproteincycle_biomd0000000072_model.species_labels"
}
],
"package": "yi2003-gproteincycle",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "The paper describes both wild-type and mutant cells of G protein cycle by using different values of G protein deactivation. It can be used to explore systemsbiology yi2003 gproteincycle BioModels0000000072 dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packageyi2003-gproteincycle
Created2026-05-17
Updated2026-06-13
immunologysystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother