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The model is first model of tissue level cellular immune responses to H. pylori in the publication, 'Modeling the role of lanthionine synthetase C-like 2 (LANCL2) in the modulation of immune responses.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_interferon_gamma",
"label": "Initial Interferon Gamma",
"units": "native source value",
"default": 10000,
"maps_to": "immunology_sbml_leber2016_host_immune_response_h_pylori_infectio_model1611160002_model.initial_interferon_gamma",
"description": "Initial Interferon Gamma. Sets the initial value of bundled SBML species `s142`."
},
{
"name": "initial_unresolved_infection_observable_1",
"label": "Initial Unresolved Infection Observable 1",
"units": "native source value",
"default": 100000000,
"maps_to": "immunology_sbml_leber2016_host_immune_response_h_pylori_infectio_model1611160002_model.initial_unresolved_infection_observable_1",
"description": "Initial Unresolved Infection Observable 1. Sets the initial value of bundled SBML species `s1`."
},
{
"name": "initial_hplumdead",
"label": "Initial Hplumdead",
"units": "native source value",
"default": 0,
"maps_to": "immunology_sbml_leber2016_host_immune_response_h_pylori_infectio_model1611160002_model.initial_hplumdead",
"description": "Initial Hplumdead. Sets the initial value of bundled SBML species `s47`."
},
{
"name": "initial_tolb_signaling_component",
"label": "Initial Tolb Signaling Component",
"units": "native source value",
"default": 0,
"maps_to": "immunology_sbml_leber2016_host_immune_response_h_pylori_infectio_model1611160002_model.initial_tolb_signaling_component",
"description": "Initial Tolb Signaling Component. Sets the initial value of bundled SBML species `s82`."
}
],
"outputs": [
{
"name": "interferon_gamma",
"maps_to": "immunology_sbml_leber2016_host_immune_response_h_pylori_infectio_model1611160002_model.interferon_gamma"
},
{
"name": "unresolved_infection_observable_1",
"maps_to": "immunology_sbml_leber2016_host_immune_response_h_pylori_infectio_model1611160002_model.unresolved_infection_observable_1"
},
{
"name": "hplumdead",
"maps_to": "immunology_sbml_leber2016_host_immune_response_h_pylori_infectio_model1611160002_model.hplumdead"
},
{
"name": "tolb_signaling_component",
"maps_to": "immunology_sbml_leber2016_host_immune_response_h_pylori_infectio_model1611160002_model.tolb_signaling_component"
},
{
"name": "total_t",
"maps_to": "immunology_sbml_leber2016_host_immune_response_h_pylori_infectio_model1611160002_model.total_t"
},
{
"name": "state",
"maps_to": "immunology_sbml_leber2016_host_immune_response_h_pylori_infectio_model1611160002_model.state"
},
{
"name": "summary",
"maps_to": "immunology_sbml_leber2016_host_immune_response_h_pylori_infectio_model1611160002_model.summary"
},
{
"name": "species_labels",
"maps_to": "immunology_sbml_leber2016_host_immune_response_h_pylori_infectio_model1611160002_model.species_labels"
}
]
},
"title": "Leber2016 - Host immune response - H.pylori infection Lab",
"models": [
{
"path": "models/core",
"alias": "immunology_sbml_leber2016_host_immune_response_h_pylori_infectio_model1611160002_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.immunology_sbml_leber2016_host_immune_response_h_pylori_infectio_model1611160002_model_state"
],
"from": "immunology_sbml_leber2016_host_immune_response_h_pylori_infectio_model1611160002_model.state"
},
{
"to": [
"visualisation.immunology_sbml_leber2016_host_immune_response_h_pylori_infectio_model1611160002_model_summary"
],
"from": "immunology_sbml_leber2016_host_immune_response_h_pylori_infectio_model1611160002_model.summary"
},
{
"to": [
"visualisation.immunology_sbml_leber2016_host_immune_response_h_pylori_infectio_model1611160002_model_species_labels"
],
"from": "immunology_sbml_leber2016_host_immune_response_h_pylori_infectio_model1611160002_model.species_labels"
}
],
"package": "leber2016-host-immune-response-h-pylori-infection",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "The model is first model of tissue level cellular immune responses to H. pylori in the publication, 'Modeling the role of lanthionine synthetase C-like 2 (LANCL2) in the modulation of immune responses.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packageleber2016-host-immune-response-h-pylori-infection
Created2026-05-15
Updated2026-06-13
immunologysbmlbiomodels_ebifaithfulcuratedvisualisationother