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Systems Biology Lopez2013Extrinsic Apoptosis M1a Embedded Model1303010000Model models core biological dynamics as a OTHER simulation curated from biomodels_ebi (biomodels_ebi:MODEL1303010000), focused on system. When you run it, you can track state over time and compare response patterns across parameter settings.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_parp_bf_none_state_u",
"label": "Initial Parp Bf None State U",
"maps_to": "systemsbiology_sbml_lopez2013_extrinsic_apoptosis_m1a_embedded_model1303010000_model.initial_parp_bf_none_state_u",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `s9`."
},
{
"name": "initial_cyto_c_bf_none_state_m",
"label": "Initial Cyto C Bf None State M",
"maps_to": "systemsbiology_sbml_lopez2013_extrinsic_apoptosis_m1a_embedded_model1303010000_model.initial_cyto_c_bf_none_state_m",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `s19`."
},
{
"name": "initial_xiap_bf_none",
"label": "Initial Xiap Bf None",
"maps_to": "systemsbiology_sbml_lopez2013_extrinsic_apoptosis_m1a_embedded_model1303010000_model.initial_xiap_bf_none",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `s10`."
},
{
"name": "initial_smac_bf_none_state_m",
"label": "Initial Smac Bf None State M",
"maps_to": "systemsbiology_sbml_lopez2013_extrinsic_apoptosis_m1a_embedded_model1303010000_model.initial_smac_bf_none_state_m",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `s20`."
},
{
"name": "initial_c9_bf_none",
"label": "Initial C9 Bf None",
"maps_to": "systemsbiology_sbml_lopez2013_extrinsic_apoptosis_m1a_embedded_model1303010000_model.initial_c9_bf_none",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `s8`."
},
{
"name": "initial_apaf_bf_none_state_i",
"label": "Initial Apaf Bf None State I",
"maps_to": "systemsbiology_sbml_lopez2013_extrinsic_apoptosis_m1a_embedded_model1303010000_model.initial_apaf_bf_none_state_i",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `s5`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_lopez2013_extrinsic_apoptosis_m1a_embedded_model1303010000_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_lopez2013_extrinsic_apoptosis_m1a_embedded_model1303010000_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_lopez2013_extrinsic_apoptosis_m1a_embedded_model1303010000_model.species_labels"
},
{
"name": "parp_bf_none_state_u",
"maps_to": "systemsbiology_sbml_lopez2013_extrinsic_apoptosis_m1a_embedded_model1303010000_model.parp_bf_none_state_u"
},
{
"name": "cyto_c_bf_none_state_m",
"maps_to": "systemsbiology_sbml_lopez2013_extrinsic_apoptosis_m1a_embedded_model1303010000_model.cyto_c_bf_none_state_m"
},
{
"name": "xiap_bf_none",
"maps_to": "systemsbiology_sbml_lopez2013_extrinsic_apoptosis_m1a_embedded_model1303010000_model.xiap_bf_none"
},
{
"name": "smac_bf_none_state_m",
"maps_to": "systemsbiology_sbml_lopez2013_extrinsic_apoptosis_m1a_embedded_model1303010000_model.smac_bf_none_state_m"
},
{
"name": "c9_bf_none",
"maps_to": "systemsbiology_sbml_lopez2013_extrinsic_apoptosis_m1a_embedded_model1303010000_model.c9_bf_none"
},
{
"name": "apaf_bf_none_state_i",
"maps_to": "systemsbiology_sbml_lopez2013_extrinsic_apoptosis_m1a_embedded_model1303010000_model.apaf_bf_none_state_i"
}
]
},
"tags": [
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Lopez2013 Extrinsic Apoptosis M1a Embedded Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_lopez2013_extrinsic_apoptosis_m1a_embedded_model1303010000_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_lopez2013_extrinsic_apoptosis_m1a_embedded_model1303010000_model_state"
],
"from": "systemsbiology_sbml_lopez2013_extrinsic_apoptosis_m1a_embedded_model1303010000_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_lopez2013_extrinsic_apoptosis_m1a_embedded_model1303010000_model_summary"
],
"from": "systemsbiology_sbml_lopez2013_extrinsic_apoptosis_m1a_embedded_model1303010000_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_lopez2013_extrinsic_apoptosis_m1a_embedded_model1303010000_model_species_labels"
],
"from": "systemsbiology_sbml_lopez2013_extrinsic_apoptosis_m1a_embedded_model1303010000_model.species_labels"
}
],
"package": "lopez2013-extrinsic-apoptosis-m1a-embedded",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "Systems Biology Lopez2013Extrinsic Apoptosis M1a Embedded Model1303010000Model models core biological dynamics as a OTHER simulation curated from biomodels_ebi (biomodels_ebi:MODEL1303010000), focused on system. When you run it, you can track state over time and compare response patterns across parameter settings.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagelopez2013-extrinsic-apoptosis-m1a-embedded
Created2026-05-17
Updated2026-06-13
systemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother