About lab
One published Lab
Build with this Lab. Run it anywhere.
Use the same immutable release locally or through managed cloud execution, with its exact version and provenance preserved.
Preparing exact examples…
The properties of inositol 1,4,5-trisphosphate (IP3)-dependent intracellular calcium oscillations in pancreatic acinar cells depend crucially on the agonist used to stimulate them. It can be used to explore systemsbiology lebeau1999 ip3 dependent intracellular calcium dynamics and compare simulation behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_model_state_ca2",
"label": "Initial Model State CA2",
"maps_to": "systemsbiology_sbml_lebeau1999_ip3_dependent_intracellular_calcium_o_biomd0000000965_model.initial_model_state_ca2",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `c`."
},
{
"name": "initial_model_state_i2",
"label": "Initial Model State I2",
"maps_to": "systemsbiology_sbml_lebeau1999_ip3_dependent_intracellular_calcium_o_biomd0000000965_model.initial_model_state_i2",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `I2`."
},
{
"name": "initial_model_state_i1",
"label": "Initial Model State I1",
"maps_to": "systemsbiology_sbml_lebeau1999_ip3_dependent_intracellular_calcium_o_biomd0000000965_model.initial_model_state_i1",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `I1`."
},
{
"name": "initial_model_state_s",
"label": "Initial Model State S",
"maps_to": "systemsbiology_sbml_lebeau1999_ip3_dependent_intracellular_calcium_o_biomd0000000965_model.initial_model_state_s",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `S`."
},
{
"name": "initial_model_state_o",
"label": "Initial Model State O",
"maps_to": "systemsbiology_sbml_lebeau1999_ip3_dependent_intracellular_calcium_o_biomd0000000965_model.initial_model_state_o",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `O`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_lebeau1999_ip3_dependent_intracellular_calcium_o_biomd0000000965_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_lebeau1999_ip3_dependent_intracellular_calcium_o_biomd0000000965_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_lebeau1999_ip3_dependent_intracellular_calcium_o_biomd0000000965_model.species_labels"
},
{
"name": "ca2",
"maps_to": "systemsbiology_sbml_lebeau1999_ip3_dependent_intracellular_calcium_o_biomd0000000965_model.ca2"
},
{
"name": "model_state_i2",
"maps_to": "systemsbiology_sbml_lebeau1999_ip3_dependent_intracellular_calcium_o_biomd0000000965_model.model_state_i2"
},
{
"name": "model_state_i1",
"maps_to": "systemsbiology_sbml_lebeau1999_ip3_dependent_intracellular_calcium_o_biomd0000000965_model.model_state_i1"
},
{
"name": "model_state_s",
"maps_to": "systemsbiology_sbml_lebeau1999_ip3_dependent_intracellular_calcium_o_biomd0000000965_model.model_state_s"
},
{
"name": "model_state_o",
"maps_to": "systemsbiology_sbml_lebeau1999_ip3_dependent_intracellular_calcium_o_biomd0000000965_model.model_state_o"
}
]
},
"tags": [
"physiology",
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Lebeau1999 Ip3 Dependent Intracellular Calcium Oscillations Due To Ag Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_lebeau1999_ip3_dependent_intracellular_calcium_o_biomd0000000965_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_lebeau1999_ip3_dependent_intracellular_calcium_o_biomd0000000965_model_state"
],
"from": "systemsbiology_sbml_lebeau1999_ip3_dependent_intracellular_calcium_o_biomd0000000965_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_lebeau1999_ip3_dependent_intracellular_calcium_o_biomd0000000965_model_summary"
],
"from": "systemsbiology_sbml_lebeau1999_ip3_dependent_intracellular_calcium_o_biomd0000000965_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_lebeau1999_ip3_dependent_intracellular_calcium_o_biomd0000000965_model_species_labels"
],
"from": "systemsbiology_sbml_lebeau1999_ip3_dependent_intracellular_calcium_o_biomd0000000965_model.species_labels"
}
],
"package": "lebeau1999-ip3-dependent-intracellular-calcium-oscillat-e5d26480",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "The properties of inositol 1,4,5-trisphosphate (IP3)-dependent intracellular calcium oscillations in pancreatic acinar cells depend crucially on the agonist used to stimulate them. It can be used to explore systemsbiology lebeau1999 ip3 dependent intracellular calcium dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagelebeau1999-ip3-dependent-intracellular-calcium-oscillat-e5d26480
Created2026-05-17
Updated2026-06-13
physiologysystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother