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Its a mathematical model presenting the interaction between a growing tumor and immune system. Model involves tumor cells, dendritic cell, helper Tcells, regulatory Tcells, effector cells and certain.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_memtcell",
"label": "Initial Memtcell",
"units": "native source value",
"default": 10000000,
"maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.initial_memtcell",
"description": "Initial Memtcell. Sets the initial value of bundled SBML species `M`."
},
{
"name": "initial_memhelpertcells",
"label": "Initial Memhelpertcells",
"units": "native source value",
"default": 6000000,
"maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.initial_memhelpertcells",
"description": "Initial Memhelpertcells. Sets the initial value of bundled SBML species `Mh`."
},
{
"name": "initial_memeffectorcells",
"label": "Initial Memeffectorcells",
"units": "native source value",
"default": 3000000,
"maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.initial_memeffectorcells",
"description": "Initial Memeffectorcells. Sets the initial value of bundled SBML species `Me`."
},
{
"name": "initial_regmemtcell",
"label": "Initial Regmemtcell",
"units": "native source value",
"default": 1000000,
"maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.initial_regmemtcell",
"description": "Initial Regmemtcell. Sets the initial value of bundled SBML species `Mr`."
},
{
"name": "tumor_growth_rate",
"label": "Tumor Growth Rate",
"units": "unit_0",
"default": 333,
"maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.tumor_growth_rate",
"description": "Tumor Growth Rate. Sets bundled SBML parameter `gamma`."
},
{
"name": "tumor_cell_killing_rate",
"label": "Tumor Cell Killing Rate",
"units": "unit_1",
"default": 1.2,
"maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.tumor_cell_killing_rate",
"description": "Tumor Cell Killing Rate. Sets bundled SBML parameter `k2`."
},
{
"name": "tumor_cell_killing_rate_2",
"label": "Tumor Cell Killing Rate 2",
"units": "unit_1",
"default": 11,
"maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.tumor_cell_killing_rate_2",
"description": "Tumor Cell Killing Rate 2. Sets bundled SBML parameter `k3`."
}
],
"outputs": [
{
"name": "memtcell",
"maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.memtcell"
},
{
"name": "memhelpertcells",
"maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.memhelpertcells"
},
{
"name": "memeffectorcells",
"maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.memeffectorcells"
},
{
"name": "regmemtcell",
"maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.regmemtcell"
},
{
"name": "source",
"maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.source"
},
{
"name": "state",
"maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.state"
},
{
"name": "summary",
"maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.summary"
},
{
"name": "species_labels",
"maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.species_labels"
}
]
},
"title": "Nwabugwu2013 - A Tumor-Immune Mathematical Model of CD4+ T Helper Cell Lab",
"models": [
{
"path": "models/core",
"alias": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model_state"
],
"from": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.state"
},
{
"to": [
"visualisation.immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model_summary"
],
"from": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.summary"
},
{
"to": [
"visualisation.immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model_species_labels"
],
"from": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.species_labels"
}
],
"package": "nwabugwu2013-a-tumor-immune-mathematical-model-of-cd4plus",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "Its a mathematical model presenting the interaction between a growing tumor and immune system. Model involves tumor cells, dendritic cell, helper Tcells, regulatory Tcells, effector cells and certain.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagenwabugwu2013-a-tumor-immune-mathematical-model-of-cd4plus
Created2026-05-15
Updated2026-06-13
immunologysbmlbiomodels_ebifaithfulcuratedvisualisationother