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Heldt2002 Orthostatic Stress - Lumped Parameter Circulation Lab

About lab

One published Lab

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Use the same immutable release locally or through managed cloud execution, with its exact version and provenance preserved.

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Heldt et al. (2002) lumped-parameter circulation (LPC) model tracking aortic pressure, mean arterial pressure, and aortic flow under orthostatic stress.

Manifest

{
  "description": "Heldt et al. (2002) lumped-parameter circulation (LPC) model tracking aortic pressure, mean arterial pressure, and aortic flow under orthostatic stress.",
  "io": {
    "inputs": [
      {
        "maps_to": "heldt2002_orthostaticstress_lpc.heart_rate",
        "name": "heart_rate"
      },
      {
        "maps_to": "heldt2002_orthostaticstress_lpc.integration_step",
        "name": "integration_step"
      },
      {
        "maps_to": "heldt2002_orthostaticstress_lpc.peak_lv_elastance",
        "name": "peak_lv_elastance"
      }
    ],
    "outputs": [
      {
        "maps_to": "heldt2002_orthostaticstress_lpc.cardiac_output",
        "name": "cardiac_output"
      },
      {
        "maps_to": "heldt2002_orthostaticstress_lpc.mean_arterial_pressure",
        "name": "mean_arterial_pressure"
      },
      {
        "maps_to": "heldt2002_orthostaticstress_lpc.state",
        "name": "state"
      },
      {
        "maps_to": "heldt2002_orthostaticstress_lpc.summary",
        "name": "summary"
      }
    ]
  },
  "models": [
    {
      "alias": "heldt2002_orthostaticstress_lpc",
      "parameters": {
        "integration_step": 0.05,
        "model_path": "data/MODEL1006230113.xml"
      },
      "path": "models/core"
    },
    {
      "alias": "visualisation",
      "path": "models/visualisation"
    }
  ],
  "package": "heldt2002-lpc",
  "runtime": {
    "communication_step": 1,
    "duration": 60,
    "initial_inputs": {}
  },
  "schema_version": "2.0",
  "title": "Heldt2002 Orthostatic Stress - Lumped Parameter Circulation Lab",
  "version": "1.0.0",
  "wiring": [
    {
      "from": "heldt2002_orthostaticstress_lpc.cardiac_output",
      "to": [
        "visualisation.heldt2002_orthostaticstress_lpc_cardiac_output"
      ]
    },
    {
      "from": "heldt2002_orthostaticstress_lpc.mean_arterial_pressure",
      "to": [
        "visualisation.heldt2002_orthostaticstress_lpc_mean_arterial_pressure"
      ]
    },
    {
      "from": "heldt2002_orthostaticstress_lpc.state",
      "to": [
        "visualisation.heldt2002_orthostaticstress_lpc_state"
      ]
    },
    {
      "from": "heldt2002_orthostaticstress_lpc.summary",
      "to": [
        "visualisation.heldt2002_orthostaticstress_lpc_summary"
      ]
    },
    {
      "from": "heldt2002_orthostaticstress_lpc.visualisation_aux",
      "to": [
        "visualisation.heldt2002_orthostaticstress_lpc_visualisation_aux"
      ]
    }
  ]
}

Runtime

Duration60
Comms Step1

Runs

Total6
Completed6
Failed0

Metadata

Packageheldt2002-lpc
Created2026-05-04
Updated2026-06-13
biomechanicscardiovascularlumped-parametersbmlbiomodels_ebifaithfulvisualisationheldt2002other