Stephanou2019 Ph As A Potential Therapeutic Target To Improve Temozolomi Lab

{
  "io": {
    "inputs": [
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        "name": "initial_mtic_m_i",
        "label": "Initial Mtic M I",
        "maps_to": "systemsbiology_sbml_stephanou2019_ph_as_a_potential_therapeutic_targ_model1909300003_model.initial_mtic_m_i",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `MTIC_M_i`."
      },
      {
        "name": "initial_dna_adducts",
        "label": "Initial DNA Adducts",
        "maps_to": "systemsbiology_sbml_stephanou2019_ph_as_a_potential_therapeutic_targ_model1909300003_model.initial_dna_adducts",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `DNA_adducts`."
      },
      {
        "name": "initial_cation_c_i",
        "label": "Initial Cation C I",
        "maps_to": "systemsbiology_sbml_stephanou2019_ph_as_a_potential_therapeutic_targ_model1909300003_model.initial_cation_c_i",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Cation_C_i`."
      },
      {
        "name": "initial_tmz_intracellular_dynamics_t_i",
        "label": "Initial Tmz Intracellular Dynamics T I",
        "maps_to": "systemsbiology_sbml_stephanou2019_ph_as_a_potential_therapeutic_targ_model1909300003_model.initial_tmz_intracellular_dynamics_t_i",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `TMZ_intracellular_dynamics_T_i`."
      },
      {
        "name": "initial_tmz_extracellular_concentration_t_o",
        "label": "Initial Tmz Extracellular Concentration T O",
        "maps_to": "systemsbiology_sbml_stephanou2019_ph_as_a_potential_therapeutic_targ_model1909300003_model.initial_tmz_extracellular_concentration_t_o",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `TMZ_extracellular_concentration_T_o`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_stephanou2019_ph_as_a_potential_therapeutic_targ_model1909300003_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_stephanou2019_ph_as_a_potential_therapeutic_targ_model1909300003_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_stephanou2019_ph_as_a_potential_therapeutic_targ_model1909300003_model.species_labels"
      },
      {
        "name": "mtic_m_i",
        "maps_to": "systemsbiology_sbml_stephanou2019_ph_as_a_potential_therapeutic_targ_model1909300003_model.mtic_m_i"
      },
      {
        "name": "dna_adducts",
        "maps_to": "systemsbiology_sbml_stephanou2019_ph_as_a_potential_therapeutic_targ_model1909300003_model.dna_adducts"
      },
      {
        "name": "cation_c_i",
        "maps_to": "systemsbiology_sbml_stephanou2019_ph_as_a_potential_therapeutic_targ_model1909300003_model.cation_c_i"
      },
      {
        "name": "tmz_intracellular_dynamics_t_i",
        "maps_to": "systemsbiology_sbml_stephanou2019_ph_as_a_potential_therapeutic_targ_model1909300003_model.tmz_intracellular_dynamics_t_i"
      },
      {
        "name": "tmz_extracellular_concentration_t_o",
        "maps_to": "systemsbiology_sbml_stephanou2019_ph_as_a_potential_therapeutic_targ_model1909300003_model.tmz_extracellular_concentration_t_o"
      }
    ]
  },
  "tags": [
    "oncology",
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Stephanou2019 Ph As A Potential Therapeutic Target To Improve Temozolomi Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "systemsbiology_sbml_stephanou2019_ph_as_a_potential_therapeutic_targ_model1909300003_model"
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
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      "from": "systemsbiology_sbml_stephanou2019_ph_as_a_potential_therapeutic_targ_model1909300003_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_stephanou2019_ph_as_a_potential_therapeutic_targ_model1909300003_model_summary"
      ],
      "from": "systemsbiology_sbml_stephanou2019_ph_as_a_potential_therapeutic_targ_model1909300003_model.summary"
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      "from": "systemsbiology_sbml_stephanou2019_ph_as_a_potential_therapeutic_targ_model1909300003_model.species_labels"
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  ],
  "package": "stephanou2019-ph-as-a-potential-therapeutic-target-to-i-62668e45",
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "version": "1.0.0",
  "description": "Abstract:Despite intensive treatments including temozolomide (TMZ) administration, glioblastoma patient prognosis remains dismal and innovative therapeutic strategies are urgently needed. It can be used to explore systemsbiology stephanou2019 ph as a potential dynamics and compare simulation behavior across conditions.",
  "schema_version": "2.0"
}