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This model is according to the paper Computational modeling reveals how interplay between components of a GTPase-cycle module regulates signal transduction by Bornheimer et al 2004.The figure 3 is rep. It can be used to explore systemsbiology bornheimer2004 gtpasecycle BioModels0000000086 dynamics and compare simulation behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_model_state_pi",
"label": "Initial Model State Pi",
"maps_to": "systemsbiology_sbml_bornheimer2004_gtpasecycle_biomd0000000086_model.initial_model_state_pi",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `species_7`."
},
{
"name": "initial_model_state_t",
"label": "Initial Model State T",
"maps_to": "systemsbiology_sbml_bornheimer2004_gtpasecycle_biomd0000000086_model.initial_model_state_t",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `species_3`."
},
{
"name": "initial_model_state_d",
"label": "Initial Model State D",
"maps_to": "systemsbiology_sbml_bornheimer2004_gtpasecycle_biomd0000000086_model.initial_model_state_d",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `species_8`."
},
{
"name": "initial_model_state_r",
"label": "Initial Model State R",
"maps_to": "systemsbiology_sbml_bornheimer2004_gtpasecycle_biomd0000000086_model.initial_model_state_r",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `species_4`."
},
{
"name": "initial_model_state_g",
"label": "Initial Model State G",
"maps_to": "systemsbiology_sbml_bornheimer2004_gtpasecycle_biomd0000000086_model.initial_model_state_g",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `species_1`."
},
{
"name": "initial_model_state_rgd",
"label": "Initial Model State Rgd",
"maps_to": "systemsbiology_sbml_bornheimer2004_gtpasecycle_biomd0000000086_model.initial_model_state_rgd",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `species_13`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_bornheimer2004_gtpasecycle_biomd0000000086_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_bornheimer2004_gtpasecycle_biomd0000000086_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_bornheimer2004_gtpasecycle_biomd0000000086_model.species_labels"
},
{
"name": "model_state_pi",
"maps_to": "systemsbiology_sbml_bornheimer2004_gtpasecycle_biomd0000000086_model.model_state_pi"
},
{
"name": "model_state_t",
"maps_to": "systemsbiology_sbml_bornheimer2004_gtpasecycle_biomd0000000086_model.model_state_t"
},
{
"name": "model_state_d",
"maps_to": "systemsbiology_sbml_bornheimer2004_gtpasecycle_biomd0000000086_model.model_state_d"
},
{
"name": "model_state_r",
"maps_to": "systemsbiology_sbml_bornheimer2004_gtpasecycle_biomd0000000086_model.model_state_r"
},
{
"name": "model_state_g",
"maps_to": "systemsbiology_sbml_bornheimer2004_gtpasecycle_biomd0000000086_model.model_state_g"
},
{
"name": "rgd",
"maps_to": "systemsbiology_sbml_bornheimer2004_gtpasecycle_biomd0000000086_model.rgd"
}
]
},
"tags": [
"signaling",
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Bornheimer2004 Gtpasecycle Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_bornheimer2004_gtpasecycle_biomd0000000086_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_bornheimer2004_gtpasecycle_biomd0000000086_model_state"
],
"from": "systemsbiology_sbml_bornheimer2004_gtpasecycle_biomd0000000086_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_bornheimer2004_gtpasecycle_biomd0000000086_model_summary"
],
"from": "systemsbiology_sbml_bornheimer2004_gtpasecycle_biomd0000000086_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_bornheimer2004_gtpasecycle_biomd0000000086_model_species_labels"
],
"from": "systemsbiology_sbml_bornheimer2004_gtpasecycle_biomd0000000086_model.species_labels"
}
],
"package": "bornheimer2004-gtpasecycle",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "This model is according to the paper Computational modeling reveals how interplay between components of a GTPase-cycle module regulates signal transduction by Bornheimer et al 2004.The figure 3 is rep. It can be used to explore systemsbiology bornheimer2004 gtpasecycle BioModels0000000086 dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagebornheimer2004-gtpasecycle
Created2026-05-17
Updated2026-06-13
signalingsystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother