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Single-model lab wrapper for Barr2016 - All-or-nothing G1/S transition. Barr2016 - All-or-nothing G1/Stransition This model is described in the article: A Dynamical Framework for the All-or-None G1/S Transition. Barr AR, Heldt FS, Zhang T, Bakal C, Nov\u00e1k B.
Manifest
{
"io": {
"inputs": [
{
"name": "cyclin_et",
"label": "Cyclin ET",
"maps_to": "cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.cyclin_et",
"description": "Controls Cyclin ET in the lab model via `cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.cyclin_et`."
},
{
"name": "cyclin_at",
"label": "Cyclin AT",
"maps_to": "cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.cyclin_at",
"description": "Controls Cyclin AT in the lab model via `cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.cyclin_at`."
},
{
"name": "p27t",
"label": "P27T",
"maps_to": "cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.p27t",
"description": "Controls P27T in the lab model via `cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.p27t`."
},
{
"name": "emi_model_state_c",
"label": "Emi Model state C",
"maps_to": "cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.emi_model_state_c",
"description": "Controls Emi Model state C in the lab model via `cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.emi_model_state_c`."
},
{
"name": "emi1t",
"label": "Emi1T",
"maps_to": "cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.emi1t",
"description": "Controls Emi1T in the lab model via `cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.emi1t`."
},
{
"name": "cdh1dp",
"label": "Cdh1dp",
"maps_to": "cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.cdh1dp",
"description": "Controls Cdh1dp in the lab model via `cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.cdh1dp`."
}
],
"outputs": [
{
"name": "cyclin_e",
"label": "Cyclin E",
"maps_to": "cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.cyclin_e",
"description": "Tracks Cyclin E in the lab model via `cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.cyclin_e`."
},
{
"name": "cyclin_a",
"label": "Cyclin A",
"maps_to": "cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.cyclin_a",
"description": "Tracks Cyclin A in the lab model via `cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.cyclin_a`."
},
{
"name": "cyclin_ep27",
"label": "Cyclin Ep27",
"maps_to": "cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.cyclin_ep27",
"description": "Tracks Cyclin Ep27 in the lab model via `cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.cyclin_ep27`."
},
{
"name": "cyclin_ap27",
"label": "Cyclin Ap27",
"maps_to": "cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.cyclin_ap27",
"description": "Tracks Cyclin Ap27 in the lab model via `cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.cyclin_ap27`."
},
{
"name": "skp2_ubiquitin_ligase_adaptor",
"label": "Skp2 ubiquitin-ligase adaptor",
"maps_to": "cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.skp2_ubiquitin_ligase_adaptor",
"description": "Tracks Skp2 ubiquitin-ligase adaptor in the lab model via `cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.skp2_ubiquitin_ligase_adaptor`."
},
{
"name": "phosphorylated_cdh1",
"label": "Phosphorylated Cdh1",
"maps_to": "cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.phosphorylated_cdh1",
"description": "Tracks Phosphorylated Cdh1 in the lab model via `cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.phosphorylated_cdh1`."
},
{
"name": "emi1_apc_c_inhibitor",
"label": "Emi1 APC/C inhibitor",
"maps_to": "cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.emi1_apc_c_inhibitor",
"description": "Tracks Emi1 APC/C inhibitor in the lab model via `cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.emi1_apc_c_inhibitor`."
},
{
"name": "p27_cdk_inhibitor",
"label": "p27 CDK inhibitor",
"maps_to": "cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.p27_cdk_inhibitor",
"description": "Tracks p27 CDK inhibitor in the lab model via `cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.p27_cdk_inhibitor`."
},
{
"name": "cdh1_apc_c_activator",
"label": "Cdh1 APC/C activator",
"maps_to": "cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.cdh1_apc_c_activator",
"description": "Tracks Cdh1 APC/C activator in the lab model via `cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.cdh1_apc_c_activator`."
},
{
"name": "emi1_cdh1_complex",
"label": "Emi1-Cdh1 complex",
"maps_to": "cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.emi1_cdh1_complex",
"description": "Tracks Emi1-Cdh1 complex in the lab model via `cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.emi1_cdh1_complex`."
},
{
"name": "emi1_phosphorylated_cdh1_complex",
"label": "Emi1-phosphorylated Cdh1 complex",
"maps_to": "cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.emi1_phosphorylated_cdh1_complex",
"description": "Tracks Emi1-phosphorylated Cdh1 complex in the lab model via `cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.emi1_phosphorylated_cdh1_complex`."
}
]
},
"title": "Barr2016 - All-or-nothing G1/S transition Lab",
"models": [
{
"path": "models/core",
"alias": "cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model_state"
],
"from": "cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.state"
},
{
"to": [
"visualisation.cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model_summary"
],
"from": "cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.summary"
},
{
"to": [
"visualisation.cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model_species_labels"
],
"from": "cellcycle_sbml_barr2016_all_or_nothing_g1_s_transition_biomd0000000646_model.species_labels"
}
],
"package": "barr2016-g1-s-transition",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "Single-model lab wrapper for Barr2016 - All-or-nothing G1/S transition. Barr2016 - All-or-nothing G1/Stransition This model is described in the article: A Dynamical Framework for the All-or-None G1/S Transition. Barr AR, Heldt FS, Zhang T, Bakal C, Nov\\u00e1k B.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagebarr2016-g1-s-transition
Created2026-05-15
Updated2026-06-13
cellcyclesbmlbiomodels_ebifaithfulvisualisationother