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The paper describes a model of tumor-immune interaction. Created by COPASI 4.25 (Build 207) This model is described in the article: Periodically Pulsed Immunotherapy in a Mathematical Model of Tumor,.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_unresolved_tumor_observable_1",
"label": "Initial Unresolved Tumor Observable 1",
"units": "substance",
"default": 0.5,
"maps_to": "immunology_sbml_wei2017_tumor_t_cell_and_cytokine_interaction_biomd0000000778_model.initial_unresolved_tumor_observable_1",
"description": "Initial Unresolved Tumor Observable 1. Sets the initial value of bundled SBML species `T`."
},
{
"name": "initial_unresolved_tumor_observable_2",
"label": "Initial Unresolved Tumor Observable 2",
"units": "substance",
"default": 0.01,
"maps_to": "immunology_sbml_wei2017_tumor_t_cell_and_cytokine_interaction_biomd0000000778_model.initial_unresolved_tumor_observable_2",
"description": "Initial Unresolved Tumor Observable 2. Sets the initial value of bundled SBML species `I`."
},
{
"name": "initial_unresolved_tumor_observable_3",
"label": "Initial Unresolved Tumor Observable 3",
"units": "substance",
"default": 0,
"maps_to": "immunology_sbml_wei2017_tumor_t_cell_and_cytokine_interaction_biomd0000000778_model.initial_unresolved_tumor_observable_3",
"description": "Initial Unresolved Tumor Observable 3. Sets the initial value of bundled SBML species `C`."
},
{
"name": "tumor_growth_rate",
"label": "Tumor Growth Rate",
"units": "unit_0",
"default": 0.01,
"maps_to": "immunology_sbml_wei2017_tumor_t_cell_and_cytokine_interaction_biomd0000000778_model.tumor_growth_rate",
"description": "Tumor Growth Rate. Sets bundled SBML parameter `r`."
},
{
"name": "tumor_killing_rate",
"label": "Tumor Killing Rate",
"units": "unit_0",
"default": 0.1,
"maps_to": "immunology_sbml_wei2017_tumor_t_cell_and_cytokine_interaction_biomd0000000778_model.tumor_killing_rate",
"description": "Tumor Killing Rate. Sets bundled SBML parameter `d`."
},
{
"name": "immune_cell_growth_rate",
"label": "Immune Cell Growth Rate",
"units": "unit_0",
"default": 0.1,
"maps_to": "immunology_sbml_wei2017_tumor_t_cell_and_cytokine_interaction_biomd0000000778_model.immune_cell_growth_rate",
"description": "Immune Cell Growth Rate. Sets bundled SBML parameter `beta`."
},
{
"name": "immune_cell_growth_rate_2",
"label": "Immune Cell Growth Rate 2",
"units": "unit_1",
"default": 1000,
"maps_to": "immunology_sbml_wei2017_tumor_t_cell_and_cytokine_interaction_biomd0000000778_model.immune_cell_growth_rate_2",
"description": "Immune Cell Growth Rate 2. Sets bundled SBML parameter `k`."
}
],
"outputs": [
{
"name": "unresolved_tumor_observable_1",
"maps_to": "immunology_sbml_wei2017_tumor_t_cell_and_cytokine_interaction_biomd0000000778_model.unresolved_tumor_observable_1"
},
{
"name": "unresolved_tumor_observable_2",
"maps_to": "immunology_sbml_wei2017_tumor_t_cell_and_cytokine_interaction_biomd0000000778_model.unresolved_tumor_observable_2"
},
{
"name": "unresolved_tumor_observable_3",
"maps_to": "immunology_sbml_wei2017_tumor_t_cell_and_cytokine_interaction_biomd0000000778_model.unresolved_tumor_observable_3"
},
{
"name": "state",
"maps_to": "immunology_sbml_wei2017_tumor_t_cell_and_cytokine_interaction_biomd0000000778_model.state"
},
{
"name": "summary",
"maps_to": "immunology_sbml_wei2017_tumor_t_cell_and_cytokine_interaction_biomd0000000778_model.summary"
},
{
"name": "species_labels",
"maps_to": "immunology_sbml_wei2017_tumor_t_cell_and_cytokine_interaction_biomd0000000778_model.species_labels"
}
]
},
"title": "Wei2017 - tumor, T cell and cytokine interaction Lab",
"models": [
{
"path": "models/core",
"alias": "immunology_sbml_wei2017_tumor_t_cell_and_cytokine_interaction_biomd0000000778_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.immunology_sbml_wei2017_tumor_t_cell_and_cytokine_interaction_biomd0000000778_model_state"
],
"from": "immunology_sbml_wei2017_tumor_t_cell_and_cytokine_interaction_biomd0000000778_model.state"
},
{
"to": [
"visualisation.immunology_sbml_wei2017_tumor_t_cell_and_cytokine_interaction_biomd0000000778_model_summary"
],
"from": "immunology_sbml_wei2017_tumor_t_cell_and_cytokine_interaction_biomd0000000778_model.summary"
},
{
"to": [
"visualisation.immunology_sbml_wei2017_tumor_t_cell_and_cytokine_interaction_biomd0000000778_model_species_labels"
],
"from": "immunology_sbml_wei2017_tumor_t_cell_and_cytokine_interaction_biomd0000000778_model.species_labels"
}
],
"package": "wei2017-tumor-t-cell-and-cytokine-interaction",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "The paper describes a model of tumor-immune interaction. Created by COPASI 4.25 (Build 207) This model is described in the article: Periodically Pulsed Immunotherapy in a Mathematical Model of Tumor,.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagewei2017-tumor-t-cell-and-cytokine-interaction
Created2026-05-15
Updated2026-06-13
immunologysbmlbiomodels_ebifaithfulcuratedvisualisationother