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Source-faithful physiology lab for Brown, Choe, Shanahan, Czeisler, 1997. Public controls and outputs are mapped to real source symbols for source-model physiology.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_melatonin_concentration_in_the_pineal_gland",
"label": "Initial Melatonin Concentration In The Pineal Gland",
"maps_to": "physiology_cellml_brown_choe_shanahan_czeisler_1997_brownchoeshanahanczeisler1997_model.initial_melatonin_concentration_in_the_pineal_gland",
"description": "Initial value for Melatonin Concentration In The Pineal Gland. Maps to source symbol `H1`. Units: picomolar. Naming evidence: source metadata names `H1` as `melatonin concentration in the pineal gland`.",
"accepted_units": [
"picomolar"
]
},
{
"name": "initial_melatonin_concentration_in_the_plasma",
"label": "Initial Melatonin Concentration In The Plasma",
"maps_to": "physiology_cellml_brown_choe_shanahan_czeisler_1997_brownchoeshanahanczeisler1997_model.initial_melatonin_concentration_in_the_plasma",
"description": "Initial value for Melatonin Concentration In The Plasma. Maps to source symbol `H2`. Units: picomolar. Naming evidence: source metadata names `H2` as `melatonin concentration in the plasma`.",
"accepted_units": [
"picomolar"
]
}
],
"outputs": [
{
"name": "state",
"label": "Selected Source State",
"maps_to": "physiology_cellml_brown_choe_shanahan_czeisler_1997_brownchoeshanahanczeisler1997_model.state"
},
{
"name": "summary",
"label": "Simulation Summary",
"maps_to": "physiology_cellml_brown_choe_shanahan_czeisler_1997_brownchoeshanahanczeisler1997_model.summary"
},
{
"name": "trajectory",
"label": "Source Trajectory",
"maps_to": "physiology_cellml_brown_choe_shanahan_czeisler_1997_brownchoeshanahanczeisler1997_model.trajectory"
},
{
"name": "variable_labels",
"label": "Observable Labels",
"maps_to": "physiology_cellml_brown_choe_shanahan_czeisler_1997_brownchoeshanahanczeisler1997_model.variable_labels"
},
{
"name": "melatonin_concentration_in_the_pineal_gland",
"label": "Melatonin Concentration In The Pineal Gland",
"maps_to": "physiology_cellml_brown_choe_shanahan_czeisler_1997_brownchoeshanahanczeisler1997_model.melatonin_concentration_in_the_pineal_gland",
"description": "Melatonin Concentration In The Pineal Gland. Maps to source symbol `H1`. Units: picomolar. Naming evidence: source metadata names `H1` as `melatonin concentration in the pineal gland`."
},
{
"name": "melatonin_concentration_in_the_plasma",
"label": "Melatonin Concentration In The Plasma",
"maps_to": "physiology_cellml_brown_choe_shanahan_czeisler_1997_brownchoeshanahanczeisler1997_model.melatonin_concentration_in_the_plasma",
"description": "Melatonin Concentration In The Plasma. Maps to source symbol `H2`. Units: picomolar. Naming evidence: source metadata names `H2` as `melatonin concentration in the plasma`."
},
{
"name": "alpha",
"label": "Alpha",
"maps_to": "physiology_cellml_brown_choe_shanahan_czeisler_1997_brownchoeshanahanczeisler1997_model.alpha",
"description": "Alpha. Maps to source symbol `alpha`. Units: first_order_rate_constant. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "beta_c",
"label": "Beta C",
"maps_to": "physiology_cellml_brown_choe_shanahan_czeisler_1997_brownchoeshanahanczeisler1997_model.beta_c",
"description": "Beta C. Maps to source symbol `beta_C`. Units: first_order_rate_constant. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "beta_i",
"label": "Beta I",
"maps_to": "physiology_cellml_brown_choe_shanahan_czeisler_1997_brownchoeshanahanczeisler1997_model.beta_i",
"description": "Beta I. Maps to source symbol `beta_I`. Units: first_order_rate_constant. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "lamda",
"label": "Lamda",
"maps_to": "physiology_cellml_brown_choe_shanahan_czeisler_1997_brownchoeshanahanczeisler1997_model.lamda",
"description": "Lamda. Maps to source symbol `lamda`. Units: first_order_rate_constant. Naming evidence: source symbol, component, or units provide a direct public name."
}
]
},
"title": "Brown1997 - Mathematical Diurnal Variations Human Plasma Me Brownchoeshana Lab",
"models": [
{
"path": "models/core",
"alias": "physiology_cellml_brown_choe_shanahan_czeisler_1997_brownchoeshanahanczeisler1997_model",
"parameters": {
"model_path": "data/brown_choe_shanahan_czeisler_1997.cellml",
"integration_step": 0.01
}
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.physiology_cellml_brown_choe_shanahan_czeisler_1997_brownchoeshanahanczeisler1997_model_state"
],
"from": "physiology_cellml_brown_choe_shanahan_czeisler_1997_brownchoeshanahanczeisler1997_model.state"
},
{
"to": [
"visualisation.physiology_cellml_brown_choe_shanahan_czeisler_1997_brownchoeshanahanczeisler1997_model_summary"
],
"from": "physiology_cellml_brown_choe_shanahan_czeisler_1997_brownchoeshanahanczeisler1997_model.summary"
},
{
"to": [
"visualisation.physiology_cellml_brown_choe_shanahan_czeisler_1997_brownchoeshanahanczeisler1997_model_trajectory"
],
"from": "physiology_cellml_brown_choe_shanahan_czeisler_1997_brownchoeshanahanczeisler1997_model.trajectory"
},
{
"to": [
"visualisation.physiology_cellml_brown_choe_shanahan_czeisler_1997_brownchoeshanahanczeisler1997_model_variable_labels"
],
"from": "physiology_cellml_brown_choe_shanahan_czeisler_1997_brownchoeshanahanczeisler1997_model.variable_labels"
}
],
"package": "brown1997-mathematical-diurnal-variations-human-plasma-b0edf1be",
"runtime": {
"duration": 0.01,
"settle_steps": 1,
"initial_inputs": {},
"communication_step": 0.01
},
"version": "1.0.0",
"description": "Source-faithful physiology lab for Brown, Choe, Shanahan, Czeisler, 1997. Public controls and outputs are mapped to real source symbols for source-model physiology.",
"schema_version": "2.0"
}Runtime
Duration0.01
Comms Step0.01
Settle Steps1
Runs
Total0
Completed0
Failed0
Metadata
Packagebrown1997-mathematical-diurnal-variations-human-plasma-b0edf1be
Created2026-05-23
Updated2026-06-13
physiologycellmlphysiomefaithfulvisualisationother