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Baker2017 - The role of cytokines, MMPs andfibronectin fragments osteoarthritis This model is described in the article: Mathematical modelling of cytokines, MMPs and fibronectin fragments in osteoarth. It can be used to explore systemsbiology baker2017 the role of cytokines dynamics and compare simulation behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_a_cytokines",
"label": "Initial A Cytokines",
"maps_to": "systemsbiology_sbml_baker2017_the_role_of_cytokines_mmps_and_fibrone_biomd0000000928_model.initial_a_cytokines",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `solution1`."
},
{
"name": "initial_fragments",
"label": "Initial Fragments",
"maps_to": "systemsbiology_sbml_baker2017_the_role_of_cytokines_mmps_and_fibrone_biomd0000000928_model.initial_fragments",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `solution3`."
},
{
"name": "initial_model_state_mmp",
"label": "Initial Model State Mmp",
"maps_to": "systemsbiology_sbml_baker2017_the_role_of_cytokines_mmps_and_fibrone_biomd0000000928_model.initial_model_state_mmp",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `solution2`."
},
{
"name": "initial_p_cytokines",
"label": "Initial P Cytokines",
"maps_to": "systemsbiology_sbml_baker2017_the_role_of_cytokines_mmps_and_fibrone_biomd0000000928_model.initial_p_cytokines",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `solution0`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_baker2017_the_role_of_cytokines_mmps_and_fibrone_biomd0000000928_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_baker2017_the_role_of_cytokines_mmps_and_fibrone_biomd0000000928_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_baker2017_the_role_of_cytokines_mmps_and_fibrone_biomd0000000928_model.species_labels"
},
{
"name": "a_cytokines",
"maps_to": "systemsbiology_sbml_baker2017_the_role_of_cytokines_mmps_and_fibrone_biomd0000000928_model.a_cytokines"
},
{
"name": "fragments",
"maps_to": "systemsbiology_sbml_baker2017_the_role_of_cytokines_mmps_and_fibrone_biomd0000000928_model.fragments"
},
{
"name": "mmp",
"maps_to": "systemsbiology_sbml_baker2017_the_role_of_cytokines_mmps_and_fibrone_biomd0000000928_model.mmp"
},
{
"name": "p_cytokines",
"maps_to": "systemsbiology_sbml_baker2017_the_role_of_cytokines_mmps_and_fibrone_biomd0000000928_model.p_cytokines"
}
]
},
"tags": [
"immunology",
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Baker2017 The Role Of Cytokines Mmps And Fibronectin Fragments Osteo Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_baker2017_the_role_of_cytokines_mmps_and_fibrone_biomd0000000928_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_baker2017_the_role_of_cytokines_mmps_and_fibrone_biomd0000000928_model_state"
],
"from": "systemsbiology_sbml_baker2017_the_role_of_cytokines_mmps_and_fibrone_biomd0000000928_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_baker2017_the_role_of_cytokines_mmps_and_fibrone_biomd0000000928_model_summary"
],
"from": "systemsbiology_sbml_baker2017_the_role_of_cytokines_mmps_and_fibrone_biomd0000000928_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_baker2017_the_role_of_cytokines_mmps_and_fibrone_biomd0000000928_model_species_labels"
],
"from": "systemsbiology_sbml_baker2017_the_role_of_cytokines_mmps_and_fibrone_biomd0000000928_model.species_labels"
}
],
"package": "baker2017-the-role-of-cytokines-mmps-and-fibronectin-fr-f5ba09bc",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "Baker2017 - The role of cytokines, MMPs andfibronectin fragments osteoarthritis This model is described in the article: Mathematical modelling of cytokines, MMPs and fibronectin fragments in osteoarth. It can be used to explore systemsbiology baker2017 the role of cytokines dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagebaker2017-the-role-of-cytokines-mmps-and-fibronectin-fr-f5ba09bc
Created2026-05-17
Updated2026-06-13
immunologysystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother