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Source-faithful physiology lab for Aguda, B, 1999. Public controls and outputs are mapped to real source symbols for source-model physiology.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_a_cdc25_ps216",
"label": "Initial A Cdc25 Ps216",
"maps_to": "physiology_cellml_aguda_b_1999_agudab1999_model.initial_a_cdc25_ps216",
"description": "Initial value for A Cdc25 Ps216. Maps to source symbol `aCdc25Ps216`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name.",
"accepted_units": [
"dimensionless"
]
},
{
"name": "initial_chk1_p",
"label": "Initial Chk1 P",
"maps_to": "physiology_cellml_aguda_b_1999_agudab1999_model.initial_chk1_p",
"description": "Initial value for Chk1 P. Maps to source symbol `Chk1P`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name.",
"accepted_units": [
"dimensionless"
]
}
],
"outputs": [
{
"name": "state",
"label": "Selected Source State",
"maps_to": "physiology_cellml_aguda_b_1999_agudab1999_model.state"
},
{
"name": "summary",
"label": "Simulation Summary",
"maps_to": "physiology_cellml_aguda_b_1999_agudab1999_model.summary"
},
{
"name": "trajectory",
"label": "Source Trajectory",
"maps_to": "physiology_cellml_aguda_b_1999_agudab1999_model.trajectory"
},
{
"name": "variable_labels",
"label": "Observable Labels",
"maps_to": "physiology_cellml_aguda_b_1999_agudab1999_model.variable_labels"
},
{
"name": "a_cdc25_ps216",
"label": "A Cdc25 Ps216",
"maps_to": "physiology_cellml_aguda_b_1999_agudab1999_model.a_cdc25_ps216",
"description": "A Cdc25 Ps216. Maps to source symbol `aCdc25Ps216`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "chk1_p",
"label": "Chk1 P",
"maps_to": "physiology_cellml_aguda_b_1999_agudab1999_model.chk1_p",
"description": "Chk1 P. Maps to source symbol `Chk1P`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "i_cdc25_ps216",
"label": "I Cdc25 Ps216",
"maps_to": "physiology_cellml_aguda_b_1999_agudab1999_model.i_cdc25_ps216",
"description": "I Cdc25 Ps216. Maps to source symbol `iCdc25Ps216`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "i_cdc25_ps216_protein1433",
"label": "I Cdc25 Ps216 Protein1433",
"maps_to": "physiology_cellml_aguda_b_1999_agudab1999_model.i_cdc25_ps216_protein1433",
"description": "I Cdc25 Ps216 Protein1433. Maps to source symbol `iCdc25Ps216_protein1433`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "mpf",
"label": "Mpf",
"maps_to": "physiology_cellml_aguda_b_1999_agudab1999_model.mpf",
"description": "Mpf. Maps to source symbol `MPF`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "p21",
"label": "P21",
"maps_to": "physiology_cellml_aguda_b_1999_agudab1999_model.p21",
"description": "P21. Maps to source symbol `p21`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
}
]
},
"title": "Aguda1999 - G2 DNA Damage Checkpoint Agudab1999 Lab",
"models": [
{
"path": "models/core",
"alias": "physiology_cellml_aguda_b_1999_agudab1999_model",
"parameters": {
"model_path": "data/aguda_b_1999.cellml",
"integration_step": 0.01
}
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.physiology_cellml_aguda_b_1999_agudab1999_model_state"
],
"from": "physiology_cellml_aguda_b_1999_agudab1999_model.state"
},
{
"to": [
"visualisation.physiology_cellml_aguda_b_1999_agudab1999_model_summary"
],
"from": "physiology_cellml_aguda_b_1999_agudab1999_model.summary"
},
{
"to": [
"visualisation.physiology_cellml_aguda_b_1999_agudab1999_model_trajectory"
],
"from": "physiology_cellml_aguda_b_1999_agudab1999_model.trajectory"
},
{
"to": [
"visualisation.physiology_cellml_aguda_b_1999_agudab1999_model_variable_labels"
],
"from": "physiology_cellml_aguda_b_1999_agudab1999_model.variable_labels"
}
],
"package": "aguda1999-g2-dna-damage-checkpoint-agudab1999",
"runtime": {
"duration": 0.01,
"settle_steps": 1,
"initial_inputs": {},
"communication_step": 0.01
},
"version": "1.0.0",
"description": "Source-faithful physiology lab for Aguda, B, 1999. Public controls and outputs are mapped to real source symbols for source-model physiology.",
"schema_version": "2.0"
}Runtime
Duration0.01
Comms Step0.01
Settle Steps1
Runs
Total0
Completed0
Failed0
Metadata
Packageaguda1999-g2-dna-damage-checkpoint-agudab1999
Created2026-05-23
Updated2026-06-13
physiologycellmlphysiomefaithfulvisualisationother