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This is a mathematical model of pancreatic cancer which includes descriptions of regulatory T cell activity and inhibition therapy. Descriptions of cytokine induced killer immunotherapy are also inclu.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_unresolved_tumor_observable_1",
"label": "Initial Unresolved Tumor Observable 1",
"units": "native source value",
"default": 1000000000,
"maps_to": "immunology_sbml_he2017_a_mathematical_model_of_pancreatic_cancer_biomd0000000811_model.initial_unresolved_tumor_observable_1",
"description": "Initial Unresolved Tumor Observable 1. Sets the initial value of bundled SBML species `C_PCC`."
},
{
"name": "initial_unresolved_tumor_observable_2",
"label": "Initial Unresolved Tumor Observable 2",
"units": "native source value",
"default": 5600000,
"maps_to": "immunology_sbml_he2017_a_mathematical_model_of_pancreatic_cancer_biomd0000000811_model.initial_unresolved_tumor_observable_2",
"description": "Initial Unresolved Tumor Observable 2. Sets the initial value of bundled SBML species `P_PSC`."
},
{
"name": "initial_cd8",
"label": "Initial CD8",
"units": "native source value",
"default": 873600000,
"maps_to": "immunology_sbml_he2017_a_mathematical_model_of_pancreatic_cancer_biomd0000000811_model.initial_cd8",
"description": "Initial CD8. Sets the initial value of bundled SBML species `E_CD8`."
},
{
"name": "initial_killer",
"label": "Initial Killer",
"units": "native source value",
"default": 481600000,
"maps_to": "immunology_sbml_he2017_a_mathematical_model_of_pancreatic_cancer_biomd0000000811_model.initial_killer",
"description": "Initial Killer. Sets the initial value of bundled SBML species `N_Killer`."
},
{
"name": "initial_t_helper",
"label": "Initial T Helper",
"units": "native source value",
"default": 2116800000,
"maps_to": "immunology_sbml_he2017_a_mathematical_model_of_pancreatic_cancer_biomd0000000811_model.initial_t_helper",
"description": "Initial T Helper. Sets the initial value of bundled SBML species `H_T_Helper`."
}
],
"outputs": [
{
"name": "unresolved_tumor_observable_1",
"maps_to": "immunology_sbml_he2017_a_mathematical_model_of_pancreatic_cancer_biomd0000000811_model.unresolved_tumor_observable_1"
},
{
"name": "unresolved_tumor_observable_2",
"maps_to": "immunology_sbml_he2017_a_mathematical_model_of_pancreatic_cancer_biomd0000000811_model.unresolved_tumor_observable_2"
},
{
"name": "cd8",
"maps_to": "immunology_sbml_he2017_a_mathematical_model_of_pancreatic_cancer_biomd0000000811_model.cd8"
},
{
"name": "killer",
"maps_to": "immunology_sbml_he2017_a_mathematical_model_of_pancreatic_cancer_biomd0000000811_model.killer"
},
{
"name": "t_helper",
"maps_to": "immunology_sbml_he2017_a_mathematical_model_of_pancreatic_cancer_biomd0000000811_model.t_helper"
},
{
"name": "state",
"maps_to": "immunology_sbml_he2017_a_mathematical_model_of_pancreatic_cancer_biomd0000000811_model.state"
},
{
"name": "summary",
"maps_to": "immunology_sbml_he2017_a_mathematical_model_of_pancreatic_cancer_biomd0000000811_model.summary"
},
{
"name": "species_labels",
"maps_to": "immunology_sbml_he2017_a_mathematical_model_of_pancreatic_cancer_biomd0000000811_model.species_labels"
}
]
},
"title": "He2017 - A mathematical model of pancreatic cancer with two kinds of treatments Lab",
"models": [
{
"path": "models/core",
"alias": "immunology_sbml_he2017_a_mathematical_model_of_pancreatic_cancer_biomd0000000811_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.immunology_sbml_he2017_a_mathematical_model_of_pancreatic_cancer_biomd0000000811_model_state"
],
"from": "immunology_sbml_he2017_a_mathematical_model_of_pancreatic_cancer_biomd0000000811_model.state"
},
{
"to": [
"visualisation.immunology_sbml_he2017_a_mathematical_model_of_pancreatic_cancer_biomd0000000811_model_summary"
],
"from": "immunology_sbml_he2017_a_mathematical_model_of_pancreatic_cancer_biomd0000000811_model.summary"
},
{
"to": [
"visualisation.immunology_sbml_he2017_a_mathematical_model_of_pancreatic_cancer_biomd0000000811_model_species_labels"
],
"from": "immunology_sbml_he2017_a_mathematical_model_of_pancreatic_cancer_biomd0000000811_model.species_labels"
}
],
"package": "he2017-a-mathematical-model-of-pancreatic-cancer-with",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "This is a mathematical model of pancreatic cancer which includes descriptions of regulatory T cell activity and inhibition therapy. Descriptions of cytokine induced killer immunotherapy are also inclu.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagehe2017-a-mathematical-model-of-pancreatic-cancer-with
Created2026-05-15
Updated2026-06-13
immunologysbmlbiomodels_ebifaithfulcuratedvisualisationother