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Single-model lab wrapper for Chen2000_CellCycle. This a model from the article: Kinetic analysis of a molecular model of the budding yeast cell cycle. Chen KC, Csikasz-Nagy A, Gyorffy B, Val J, Novak B, Tyson JJ.
Manifest
{
"io": {
"inputs": [
{
"name": "hct1_t",
"label": "Hct1 T",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.hct1_t",
"description": "Controls Hct1 T in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.hct1_t`."
},
{
"name": "bck2_0",
"label": "Bck2 0",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.bck2_0",
"description": "Controls Bck2 0 in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.bck2_0`."
},
{
"name": "cln3_max",
"label": "Cln3 Max",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.cln3_max",
"description": "Controls Cln3 Max in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.cln3_max`."
}
],
"outputs": [
{
"name": "cln2_g1_cyclin",
"label": "Cln2 G1 cyclin",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.cln2_g1_cyclin",
"description": "Tracks Cln2 G1 cyclin in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.cln2_g1_cyclin`."
},
{
"name": "cdc20_apc_c_activator",
"label": "Cdc20 APC/C activator",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.cdc20_apc_c_activator",
"description": "Tracks Cdc20 APC/C activator in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.cdc20_apc_c_activator`."
},
{
"name": "cdc20_t",
"label": "Cdc20 T",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.cdc20_t",
"description": "Tracks Cdc20 T in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.cdc20_t`."
},
{
"name": "hct1_apc_c_activator",
"label": "Hct1 APC/C activator",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.hct1_apc_c_activator",
"description": "Tracks Hct1 APC/C activator in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.hct1_apc_c_activator`."
},
{
"name": "clb2_sic1",
"label": "Clb2 Sic1",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.clb2_sic1",
"description": "Tracks Clb2 Sic1 in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.clb2_sic1`."
},
{
"name": "sic1_t",
"label": "Sic1 T",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.sic1_t",
"description": "Tracks Sic1 T in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.sic1_t`."
},
{
"name": "clb5_sic1",
"label": "Clb5 Sic1",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.clb5_sic1",
"description": "Tracks Clb5 Sic1 in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.clb5_sic1`."
},
{
"name": "clb5_t",
"label": "Clb5 T",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.clb5_t",
"description": "Tracks Clb5 T in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.clb5_t`."
},
{
"name": "clb2_t",
"label": "Clb2 T",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.clb2_t",
"description": "Tracks Clb2 T in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.clb2_t`."
},
{
"name": "mass",
"label": "Mass",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.mass",
"description": "Tracks Mass in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.mass`."
},
{
"name": "replication_origin_state",
"label": "Replication origin state",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.replication_origin_state",
"description": "Tracks Replication origin state in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.replication_origin_state`."
},
{
"name": "budding_index",
"label": "Budding index",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.budding_index",
"description": "Tracks Budding index in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.budding_index`."
},
{
"name": "spindle_state",
"label": "Spindle state",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.spindle_state",
"description": "Tracks Spindle state in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.spindle_state`."
},
{
"name": "bck2_g1_regulator",
"label": "Bck2 G1 regulator",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.bck2_g1_regulator",
"description": "Tracks Bck2 G1 regulator in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.bck2_g1_regulator`."
},
{
"name": "clb2_mitotic_cyclin",
"label": "Clb2 mitotic cyclin",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.clb2_mitotic_cyclin",
"description": "Tracks Clb2 mitotic cyclin in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.clb2_mitotic_cyclin`."
},
{
"name": "clb5_s_phase_cyclin",
"label": "Clb5 S-phase cyclin",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.clb5_s_phase_cyclin",
"description": "Tracks Clb5 S-phase cyclin in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.clb5_s_phase_cyclin`."
},
{
"name": "cln3_start_cyclin",
"label": "Cln3 Start cyclin",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.cln3_start_cyclin",
"description": "Tracks Cln3 Start cyclin in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.cln3_start_cyclin`."
},
{
"name": "model_state_d",
"label": "Model state D",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.model_state_d",
"description": "Tracks Model state D in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.model_state_d`."
},
{
"name": "mbf_transcription_factor",
"label": "MBF transcription factor",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.mbf_transcription_factor",
"description": "Tracks MBF transcription factor in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.mbf_transcription_factor`."
},
{
"name": "mcm1_transcription_factor",
"label": "Mcm1 transcription factor",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.mcm1_transcription_factor",
"description": "Tracks Mcm1 transcription factor in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.mcm1_transcription_factor`."
},
{
"name": "sbf_transcription_factor",
"label": "SBF transcription factor",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.sbf_transcription_factor",
"description": "Tracks SBF transcription factor in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.sbf_transcription_factor`."
},
{
"name": "sic1_cdk_inhibitor",
"label": "Sic1 CDK inhibitor",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.sic1_cdk_inhibitor",
"description": "Tracks Sic1 CDK inhibitor in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.sic1_cdk_inhibitor`."
},
{
"name": "swi5_transcription_factor",
"label": "Swi5 transcription factor",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.swi5_transcription_factor",
"description": "Tracks Swi5 transcription factor in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.swi5_transcription_factor`."
},
{
"name": "va_sbf",
"label": "Va Sbf",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.va_sbf",
"description": "Tracks Va Sbf in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.va_sbf`."
},
{
"name": "vd2_model_state_c1",
"label": "Vd2 Model state C1",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.vd2_model_state_c1",
"description": "Tracks Vd2 Model state C1 in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.vd2_model_state_c1`."
},
{
"name": "vd_b2",
"label": "Vd B2",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.vd_b2",
"description": "Tracks Vd B2 in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.vd_b2`."
},
{
"name": "vd_b5",
"label": "Vd B5",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.vd_b5",
"description": "Tracks Vd B5 in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.vd_b5`."
},
{
"name": "vi_20",
"label": "Vi 20",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.vi_20",
"description": "Tracks Vi 20 in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.vi_20`."
},
{
"name": "vi_t1",
"label": "Vi T1",
"maps_to": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.vi_t1",
"description": "Tracks Vi T1 in the lab model via `cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.vi_t1`."
}
]
},
"title": "Chen2000_CellCycle Lab",
"models": [
{
"path": "models/core",
"alias": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model_state"
],
"from": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.state"
},
{
"to": [
"visualisation.cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model_summary"
],
"from": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.summary"
},
{
"to": [
"visualisation.cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model_species_labels"
],
"from": "cellcycle_sbml_chen2000_cellcycle_biomd0000000675_model.species_labels"
}
],
"package": "chen2000-budding-yeast-cell-cycle",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "Single-model lab wrapper for Chen2000_CellCycle. This a model from the article: Kinetic analysis of a molecular model of the budding yeast cell cycle. Chen KC, Csikasz-Nagy A, Gyorffy B, Val J, Novak B, Tyson JJ.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagechen2000-budding-yeast-cell-cycle
Created2026-05-15
Updated2026-06-13
cellcyclesbmlbiomodels_ebifaithfulvisualisationother